The cell biology of the plasminogen system

FASEB Journal

Volumn 9, Issue 10, 1995, Pages 939-945

  Plow, Edward F ^a   Herren, Thomas ^a   Redlttz, Alexander ^a   Miles, Lindsey A ^b   Hoover Plow, Jane L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

fibrinolysis; lipoprotein(a); plasminogen receptors; proteolysis; urokinase

Indexed keywords

CELL RECEPTOR; LIPOPROTEIN A; PLASMIN; PLASMINOGEN;

BINDING SITE; CELL ADHESION; FIBRINOLYSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 0029128394     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.9.10.7615163     Document Type: Review

References (67)

1. Miles, L. A., and Plow, E. F. (1985) Binding and activation of plasminogen on the platelet surface. J. Biol. Chem. 260, 4303-4311
2. Hajjar, K. A., Harpel, P. C., Jaffe, E. A., and Nachman, R. L. (1986) Binding of plasminogen to cultured human endothelial cells. J. Biol. Chem. 261, 11656-11662
3. Gonzalez-Gronow, M., Edelberg, J. M., and Pizzo, S. V. (1989) Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein(a) compete for the same site. Biochemistry 28, 2374-2377
4. Gonias, S. L., Geary, W. A., and VandenBerg, S. R. (1989) Plasminogen binding to rat hepatocytes in primary culture and to thin slices of rat liver. Blood 75, 729-736
5. Miles, L. A., and Plow, E. F. (1988) Plasminogen receptors: ubiquitous sites for cellular regulation of fibrinolysis. Fibrinolysis 2, 61-71
6. Miles, L. A., Dahlberg, C. M., and Plow, E. F. (1988) The cell-binding domains of plaaminogen and their function in plasma. J. Biol. Chem. 263, 11928-11934
7. Adelman, B., Rizk, A., and Hanners, E. (1988) Plasminogen interactions with platelets in plasma. Blood 72, 1530-1535
8. Burtin, P., Chavanel, G., Andre-Bougaran, J., and Gentile, A. (1987) The plasmin system in human adenocarcinomas and their metastases. A comparative immunofluorescence study. Int. J. Cancer 39, 170-178
9. Bauer, P. I., Machovich, R., Buki, K., Csonka, E., Koch, S., and Horvath, I. (1984) Interaction of plasmin with endothelial cells. Biochem. J. 218, 119-124
10. Ganz, P. R., Dupuis, D., Dudani, A. K., and Hashemi, S. (1991) Characterization of plasminogen binding to human capillary and arterial endothelial cells. Biochem. Cell. Biol. 69, 442-448
11. Miles, L. A., and Plow, E. F. (1987) Receptor mediated binding of the fibrinolytic components, plasminogen and urokinase, to peripheral blood cells. Thromb. Haemost. 58, 936-942
12. Nakajima, K., Nagata, K., Hamanoue, M., Takemoto, N., Shimada, A., and Kohsaka, S. (1993) Plasminogen-binding protein associated with the plasma membrane of cultured embryonic rat neocortical neurons. FEBS Lett. 333, 223-228
13. Plow, E. F., Freaney, D. E., Plescia, J., and Miles, L. A. (1986) The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type. J. Cell Biol. 103, 2411-2420
14. Miles, L. A., Dahlberg, C. M., Plescia, J., Felez, J., Kato, K., and Plow, E. F. (1991) Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor. Biochemistry 30, 1682-1691
15. Redlitz, A., Fowler, B. J., Plow, E. F., and Miles, L. A. (1994) The role of an enolase-related molecule in plasminogen binding to cells. Eur. J. Biochem. 227, 407-415
16. Nakajima, K., Hamanoue, M., Takemoto, N., Hattori, T., Kato, K., and Kohsaka, S. (1994) Plasminogen binds specifically lo α-enolase on rat neuronal plasma membrane. J. Neurochem. 63, 2048-2057
17. Cesarman, G. M., Guevara, C. A., and Hajjar, K. A. (1994) An endothelial cell receptor for plasminogen/tissue plasminogen activator (t-PA). II. Annexin II-medialed enhancement of t-PA-dependent plasminogen activation. J. Biol. Chem. 269, 21198-21203
18. Lottenberg, R., Broder, C. C., Boyle, M. D. P., Kain, S. J., Schroeder, B. L., and Curtiss, I. (1992) Cloning, sequence analysis, and expression in Escherichia coli of a streptococcal plasmin receptor. J. Bacteriol. 174, 5204-5210
19. Parkkinen, J., and Rauvala, H. (1991) Interactions of plasminogen and tissue plasminogen activated (t-PA) with amphoterin. Enhancement of l-PA-catalyzed plasminogen activation by amphoterin. J. Biol. Chem. 266, 16730-16735
20. Miles. L. A., Ginsberg, M. H., White, J. G., and Plow, E. F. (1986) Plasminogen interacts with human platelets through two distinct mechanisms. J. Clin. Invest. 77, 2001-2009
21. Gonzalez-Gronow, M., Gawdi, G., and Pizzo, S. V. (1994) Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts. J. Biol. Chem. 269, 4360-4366
22. Miles, L. A., Dahlberg, C. M., Levin, E. G., and Plow, E. F. (1989) Gangliosides interact directly with plasminogen and urokinase and may mediate binding of these fibrinolytic components to cells. Biochemistry 28, 9337-9343
23. Andrade-Gordon, P., and Strickland, S. (1986) Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen. Biochemistry 25, 4033-4040
24. Ellis, V., Behrendt, N., and Dano, K. (1991) Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor. J Biol. Chem. 266, 12752-12758
25. Deguchi, K., Murashima, S., Shirakawa, S., Soria, C., Soria, J., Dunn, F., and Tobelem, G. (1985) The potentiating effect of platelet on plasminogen activation by tissue plasminogen activator. Thromb. Res. 40, 853-861
26. Stricker, R. B., Wong, D., Shiv, D. T., Reyes, P. T., and Shuman, M. A. (1986) Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: effects on surface proteins and platelet aggregation. Blood 68, 275-280
27. Camacho, M., Fondanèche, M. -C., and Burtin, P. (1989) Limited proteolysis of tumor cells increases their plasmin-binding ability. FEBS Lett. 245, 21-24
28. Gonzalez-Gronow, M., Stack, S., and Pizzo, S. V. (1991) Plasmin binding to the plasminogen receptor enhances catalytic efficiency and activates the receptor for subsequent ligand binding. Arch. Biochem. Biophys. 286, 625-628
29. Hall, S. W., Humphries, J. E., and Gonias, S. L. (1991) Inhibition of cell surface receptor-bound plasmin by α2-antiplasmin and α2-macroglobulin. J. Biol. Chem. 266, 12329-12336
30. Duval-Jobe, C., and Parmely, M. J. (1994) Regulation of plasminogen activation by human U937 promonocytic cells. J. Biol. Chem. 269, 21353-21357
31. Saksela, O., and Rifkin, D. B. (1988) Cell-associated plasminogen activation: Regulation and physiological functions. Anna. Rev. Cell Biol. 4, 93-126
32. Wong, A. P., Cortez, S. L., and Baricos, W. H. (1992) Role of plasmin and gelatinase in extracellular matrix degradation by cultured rat mesangial cells. Am. J. Physiol. 263, F1112-F1118
33. Niedbala, M. J., and Picarella, M. S. (1992) Tumor necrosis factor induction of endothelial cell urokinase-type plasminogen activator mediated proteolysis of extracellular matrix and its antagonism by gamma-interferon. Blood 79, 678-687
34. Niedbala, M. J., and Sartorelli, A. C. (1990) Plasminogen activator mediated degradation of subendothelial extracellular matrix by human squamous carcinoma cell lines. Cancer Commun. 2, 189-199
35. Pepper, M. S., Sappino, A. -P., Stöcklin, R., Montesano, R., Orci, L., and Vassalli, J. -D. (1993) Upregulation of urokinase receptor expression on migrating endothelial cells. J. Cell Biol. 122, 673-684
36. Morimoto, K., Mishima, H., Nishida, T., and Otori, T. (1993) Role of urokinase type plasminogen activator (u-PA) in corneal epithelial migration. Thromb. Haemost. 69, 387-391
37. Meissauer, A., Kramer, M. D., Schirrmacher, V., and Brunner, G. (1992) Generation of cell surface-bound plasmin by cell-associated urokinase-type or secreted tissue-type plasminogen activator: a key event in melanoma cell invasiveness in vitro. Exp. Cell Res. 199, 179-190
38. Shea, T. B., and Beermann, M. L. (1992) Regulation of neuronal migration and neuritogenesis by distinct surface proteases. Relative contribution of plasmin and a thrombin-like protease. FEBS Lett. 307, 190-194
39. Kobayashi, H., Shinohara, H., Takeuchi, K., Itoh, M., Fujie, M., Saitoh, M., and Terao, T. (1994) Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis. Cancer Res. 54, 844-849
40. Cohen, R. L., Xi, X. -P., Crowley, C. W., Lucas, B. K., Levinson, A. D., and Shuman, M. A. (1991) Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells. Blood 78, 479-487
41. Karikó, K., Kuo, A., Boyd, D., Okada, S. S., Cines, D. B., and Barnathan, E. S. (1993) Overexpression of urokinase receptor increases matrix invasion without altering cell migration in a human osteosarcoma cell line. Cancer Res. 53, 3109-3117
42. Jackson, C. L., and Reidy, M. A. (1992) The role of plasminogen activation in smooth muscle cell migration after arterial injury. Ann. N.Y. Acad. Sci. 667, 141-150
43. Falcone, D. J., McCaffrey,T. A., Haimovitz-Friedman, A., Vergilio, J. -A., and Nicholson, A. C. (1993) Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation. J. Biol. Chem. 268, 11951-11958
44. Taipale, J., Koli, K., and Keski-Oja, J. (1992) Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasls and fibrosarcoma cells by plasmin and thrombin. J. Biol. Chem. 267, 25378-25384
45. Conforti, G., Dominguez-Jimenez, C., Ronne, Z., Hoyer-Hansen, G., and Dejana, E. (1994) Cell-surface plasminogen activation causes a retraction of in vitro cultured human umbilical vein endothelial cell monolayer. Blood 83, 994-1005
46. Ryan, T. J., Lai, L., and Malik, A. B. (1992) Plasmin generation induces neutrophil aggregation: dependence on the catalytic and lysine binding sites. J. Cell. Physiol. 151, 255-261
47. O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y., Sage, E. H., and Folkman, J. (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis Lung carcinoma. Cell 79, 315-328
48. Miles, L. A., Levin, E. G., Plescia, J., Collen, D., and Plow, E. F. (1988) Plasminogen receptors, urokinase receptors, and their modulation on human endothelial cells. Blood 72, 628-635
49. Pollanen, J.(1989) Down-regulation of plasmin receptors on human sarcoma cells by glucocorticoids. J. Biol. Chem. 264, 5628-5632
50. Felez, J., Miles, L. A., Plescia, J., and Plow, E. F. (1990) Regulation of plasminogen receptor expression on human monocytes and monocytoid cell lines. J. Cell Biol. 111, 1673-1683
51. 3 and their combination. Thromb. Res. 69, 353-359
52. Kim, B. S., Plow, E. F., and Miles, L. A. (1992) Regulation of plasminogen receptor expression on monocytoid THP-1 cells by adherence to extracellular matrix proteins. Circulation 86, 1-148a(Abslract)
53. Skidgel, R. A.(1988) Basic carboxypeptidases: regulators of peptide hormone activity. Trends Pharmacol. Sci. 9, 299-304
54. Utermann, G.(1989) The mysteries of lipoprotein(a). Science 246, 904-910
55. Mclean, J. W., Tomlinson, J. E., Kuang, W. -J., Eaton, D. L., Chen, E. Y., Fless, G. M., Scanu, A. M., and Lawn, R. M. (1987) cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature 330, 132-137
56. 37. J. Clin. Invest. 91, 283-291
57. Scanu, A. M., Pfaffinger, D., Lee, J. C., and Hinman, J. (1994) A single point mutation (Trp72-Arg) in human apo(a) kringle 4-37 associated with a lysine binding defect in Lp(a). Biochim. Biophys. Acta Mol. Basis Dis. 1227, 41-45
58. Hoover-Plow, J. L. Miles, L. A., Fless, G. M., Scanu, A. M., and Plow, E. F. (1993) Comparison of the lysine binding functions of lipoprotein(a) and plasminogen. Biochemistry 32, 13681-13687
59. Miles, L A., and Plow, E. F. (1990) Lp(a): an interloper into the fibrinolytic system? Thromb. Haemost. 63, 331-335
60. Scanu, A.(1992) Lipoprotein(a): a genetic risk factor for premature coronary heart disease. JAMA 267, 3326-3329
61. Edelberg, J. M., Gonzalez-Gronow, M., and Pizzo, S. V. (1989) Lipoprotein a inhibits streptokinase-mediated activation of human plasminogen. Biochemistry 28, 2370-2374
62. Liu, J., Harpel, P. C., Pannell, R., and Gurewich, V. (1993) Lipoprotein(a): a kinetic study of its influence on fibrin-dependent plasminogen activation by prourokinase or tissue plasminogen activator. Biochemistry 32, 9694-9700
63. Kojima, S., Harpel, P. C., and Rifkin, D. B. (1991) Lipoprolein (a) inhibits the generation of transforming growth factor β: an endogenous inhibitor of smooth muscle cell migration. J. Cell Biol. 113, 1439-1445
64. Miles, L. A., Fless, G. M., Levin, E. G., Scanu, A. M., and Plow, E. F. (1989) A potential basis for the thrombotic risks associated with lipoprotein(a). Nature 339, 301-303
65. Hajjar, K. A., Gavish, D., Breslow, J. L., and Nachman, R. L. (1989) Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis. Nature 339, 303-305
66. Miles, L. A., Fless, G. M., Scanu, A. M., Baynham, P., Sebald, M. T., Skocir, P., Curtiss, L.K., Levin, E. G., Hoover-Plow, J. L., and Plow, E. F. (1995) Interaction of Lp(a) with plasminogen binding sites on cells. Thromb. Haemost. 73, 458-465
67. Carmeliet, P., and Collen, D. (1995) Gene targeting and gene transfer studies of the plasminogen/plasmin system: implications in thrombosis, hemostasis, neointima formation and atherosclerosis. FASEB J. 9, 934-938