Rhabdomyolysis from the coadministration of lovastatin and the antifungal agent itraconazole

New England Journal of Medicine

Volumn 333, Issue 10, 1995, Pages 664-665

  Lees, Robert S ^a   Lees, Ann M ^a  

^a Boston Heart Foundation ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ITRACONAZOLE; MEVINOLIN; NICOTINIC ACID; UBIQUINONE;

ADULT; CASE REPORT; CORONARY ARTERY DISEASE; CORONARY RISK; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; INFECTION RISK; LETTER; PRIORITY JOURNAL; RHABDOMYOLYSIS;

CASE REPORT; DRUG INTERACTIONS; FEMALE; HUMAN; ITRACONAZOLE; LOVASTATIN; MIDDLE AGE; NIACIN; RHABDOMYOLYSIS;

EID: 0029126528     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199509073331015     Document Type: Letter

References (4)

1. Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-1389
2. Illingworth DR, Tobert JA A review of clinical trials comparing HMG-CoA reductase inhibitors. Clin Ther 1994; 16: 366-385
3. Folkers K, Langsjoen P, Willis R, Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci U S A 1990; 87: 8931-8934
4. Lorenz RT, Parks LW Effects of lovastatin (mevinolin) on sterol levels and on activity of azoles in Saccharomyces cerevisiae. Antimicrob Agents Chemother 1990; 34: 1660-1665