Loss of Heterozygosity at Chromosome 11q in Lung Adenocarcinoma: Identification of Three Independent Regions1

Cancer Research

Volumn 55, Issue 18, 1995, Pages 3988-3991

  Rasio, Debora ^a   Negrini, Massimo ^a   Croce, Carlo M ^a   Manenti, Giacomo ^b   Dragani, Tommaso A ^b  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CANCER RISK; CHROMOSOME 11Q; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MOLECULAR CLONING; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADULT; AGED; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 11; HUMAN; LUNG NEOPLASMS; MIDDLE AGE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029124902     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Boring, C. C., Squires, T. S., and Tong, T. Cancer statistics, 1993. Calif. Cancer J. Clin., 43: 7–26, 1993.
2. Travis, W. D., Travis, L. B., and Devesa, S. S. Lung cancer. Cancer (Phila.), 75(Suppl.l): 191–202, 1995.
3. Lukeis, R., Irving, L., Garson, M., and Hasthorpe, S. Cytogenetics of non-small cell cancer: analysis of consistent non-random abnormalities. Genes Chromosomes & Cancer, 2: 116–124, 1990.
4. Testa, J. R., Siegfried, J. M., Liu, Z., Hunt, J. D., Feder, M. M., Lirwin, S., Zhou, J. Y., Taguchi, T., and Keller, S. M. Cytogenetics analyses of 63 non-small cell lung carcinomas: recurrent chromosome alterations amid frequent and widespread genomic upheaval. Genes Chromosomes & Cancer, 11: 178–194, 1994.
5. Carbone, D. P., and Minna, J. D. The molecular genetics of lung cancer. Adv. Intern. Med., 37: 153–171, 1992.
6. Tsuchiya, E., Nakamura, Y., Weng, S. Y., Nakagawa, K., Tsuchiya, S., Sugano, H., and Kitagawa, T. Allelotype of non-small cell lung carcinoma-comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma. Cancer Res., 52: 2478–2481, 1992.
7. Emi, M., Fujiwara, Y., Nakajima, T., Tsuchiya, E., Tsuda, H., Hirohashi, S., Maeda, Y., Tsuruta, K., Miyaki, M., and Nakamura, Y. Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer. Cancer Res., 52: 5368–5372, 1992.
8. Merlo, A., Gabrielson, E., Askin, F., and Sidransky, D. Frequent loss of chromosome 9 in human primary non-small cell lung cancer. Cancer Res., 54: 640–642, 1994.
9. Ludwig, C. U., Raefle, G., Dalquen, P., Stulz, P., Stahel, R., and Obrecht, J.-P. Allelic loss on the short arm of chromosome 11 in non-small-cell lung cancer. Int. J. Cancer, 49: 661–665, 1991.
10. Bepler, G., and Garcia-Blanco, M. A. Three tumor-suppressor regions on chromosome lip identified by high-resolution deletion mapping in human non-small-cell lung cancer. Proc. Natl. Acad. Sci. USA, 91: 5513–5517, 1994.
11. Fong, K. M., Zimmerman, P. V., and Smith, P. J. Correlation of loss of heterozygosity at 1 lp with tumor progression and survival in non-small cell lung cancer. Genes Chromosomes & Cancer, 10: 183–189, 1994.
12. Iizuka, M., Sugiyama, Y., Shiraishi, M., Jones, C., and Sekiya, T. Allelic losses in human chromosome 11 in lung cancer. Genes Chromosome & Cancer, 13: 40–46, 1995.
13. Parshad, R., Price, F. M., Oshimura, M., Barrett, J. C., Satoh, H., Weissman, B. E., Stanbridge, E. J., and Sanford, K. K. Complementation of a DNA repair deficiency in six human tumor cell lines by chromosome 11. Hum. Genet., 88: 524–528, 1992.
14. Satoh, H., Lamb, P. W., Dong, J.-T., Everitt, J., Boreiko, C., Oshimura, M., and Barrett, J. C. Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer. Mol. Carcinog., 7: 157–164, 1993.
15. Negrini, M., Sabbioni, S., Possati, L., Rattan, S., Corallini, A., Barbanti-Brodano, G., and Croce, C. M. Suppression of breast cancer cells tumorigenicity by microcell-mediated chromosome transfer: studies on chromosomes 6 and 11. Cancer Res., 54: 1331–1336, 1994.
16. Negrini, M., Rasio, D., Hampton, G. M., Sabbioni, S., Rattan, S., Carter, S. L., Rosenberg, A. L., Schwartz, G. F., Shiloh, Y., Cavenee, W. K., and Croce, C. M. Cancer Res., 55: 3003–3007, 1995.
17. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
18. James, M. R., Richard, C. W., III, Schott, J. J., Yousry, C., Clark, K., Bell, J., Terwilliger, J. D., Hazan, J., Dubay, C., Vignal, A., Agrapart, M., Imai, T., Nakamura, Y., Polymeropoulos, M., Weissenbach, J., Cox, D. R., and Lathrop, G. M. A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nature Genet., 8: 70–76, 1994.
19. van Heyningen, V., and Little, P. F. R. Report of the Fourth International Workshop on Human Chromosome 11 Mapping, 1994. Cytogenet. Cell Genet., 69: 127–158, 1995.
20. Hampton, G. M., Mannermaa, A., Winqvist, R., Alavaikko, M., Blanco, G., Taskinen, P. J., Kiniviemi, H., Newsham, I., Cavenee, W. K., and Evans, G. A. Loss of heterozygosity in sporadic human breast carcinoma: a common region between 1 lq22 and llq23.3. Cancer Res., 54: 4586–4589, 1994.
21. Carter, S. L., Negrini, M., Baffa, R., Gillum, D. R., Rosenberg, A. L., Schwartz, G. F., and Croce, C. M. Loss of heterozygosity at 1 Iq22-q23 in breast cancer. Cancer Res., 54: 6270–6274, 1994.
22. Hampton, G. M., Penny, L. A., Baergen, L. N., Larson, A., Brewer, C., Liao, S., Busby-Earle, R. M. C., Williams, A. W. R., Steel, C. M., Bird, C. C., Stanbridge, E. J., and Evans, G. A. Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor suppressor gene to chromosome 11q22-q24. Proc. Natl. Acad. Sci. USA, 91: 6953–6957, 1994.
23. Foulkes, W. D., Campbell, I. G., Stamp, G. W. H., and Trowsdale, J. Loss of heterozigosity and amplification on chromosome 1 lq in human ovarian cancer. Br. J. Cancer, 67: 268–273, 1993.
24. Keldysh, P. L., Dragani, T. A., Fleishman, E. W., Konstantinova, L. N., Perevoschi-kov, A. G., Pierotti, M. A., Delia Porta, G., and Kopnin, B. P. 1 lq deletions in human colorectal carcinomas: cytogenetics and restriction fragment length polymorphism analysis. Genes Chromosome & Cancer, 6: 45–50, 1993.
25. Tomlinson, I. P. M., Gammack, A. J., Stickland, J. E., Mann, G. J., Mackie, R. M., Kefford, R. F., and McGee, J. O. Loss of heterozigosity in malignant melanoma at loci on chromosome 11 and 17 implicated in the pathogenesis of other cancers. Genes Chromosome & Cancer, 7: 169–172, 1993.
26. Herbst, R. A., Larson, A., Weiss, J., Cavenee, W. K., Hampton, G. M., and Arden, K. A defined region of loss of heterozygosity at llq23 in cutaneous malignant melanoma. Cancer Res., 55: 2494–2496, 1995.
27. Rotman, G., Savitsky, K., Ziv, Y., Cole, C. G., Higgins, M. J., Bar-Am, I., Dunham, I., Bar-Shira, A., Vanagaite, L., Qin, S., Zhang, J., Nowak, N. J., Chandrasekharappa, S. C., Lehrach, H., Aviv, L., Shows, T. B., Collins, F. S., Bentley, D. R., and Shiloh, Y. A YAC contig spanning the ataxia-telangiectasia locus (groups A and C) at 11q22-q23. Genomics, 24: 234–242, 1994.
28. Swift, M., Morrell, D., Massey, R. B., and Chase, C. L. Incidence of cancer in 161 families affected by ataxia-telangiectasia. N. Engl. J. Med., 325: 1831–1836, 1991.
29. Gatti, R. A., and McConville, C. M. Sixth International Workshop on Ataxia-Telangiectasia (Meeting Report). Cancer Res., 54: 6007–6010, 1994.
30. Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., Ashkenazi, M., Pecker, I., Frydman, M., Harnik, R., Patanjali, S. R., Simmons, A., Clines, G. A., Sartiel, A., Gatti, R. A., Chessa, L., Sanal, O., Lavin, M. F., Jaspers, N. J., Taylor, A. R., Arlett, C. F., Miki, T., Weissman, S. M., Lovett, M., Collins, F. S., and Shiloh, Y. A single ataxia-telangiectasia gene with a product similar to PI 3-kinase. Science (Washington DC), 268: 1749–1752, 1995.