Addition of molecular fluorine to 2-azabicyclo[2.2.1]hept-5-en-3-one and related compounds: Synthesis of difluorinated carbocyclic nucleosides

Tetrahedron

Volumn 51, Issue 32, 1995, Pages 8783-8798

  Toyota, Akemi ^a   Aizawa, Megumi ^a   Habutani, Chie ^a   Katagiri, Nobuya ^a   Kaneko, Chikara ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOCYCLIC NUCLEOSIDE; ORGANOFLUORINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; FLUORINATION; METHODOLOGY; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0029123806     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(95)00469-O     Document Type: Article

References (39)

1. Electrophilic fluorination of some steroidal ?,?-unsaturated ketones
2. Selective substitution of aliphatic remote tertiary hydrogens by fluorine
3. Synthesis of 5-fluoro-1,3-dioxin-4-ones: versatile building blocks of fluorinated compounds
4. Mechanism ofSYN addition of molecular fluorine to ethylene. Anab initio MO study
5. Direct synthesis of fluoro-bicyclic compounds with fluorine
6. A New Method for the Stereoselective Synthesis of Nucleosides by Means of Sodium Borohydride Mediated Reductive C-C or C-N Bond Cleavage Reaction
7. Efficient, stereocontrolled total syntheses of racemic and natural brefeldin-A
8. Potential use of carbocyclic nucleosides for the treatment of AIDS: chemo-enzymatic syntheses of the enantiomers of carbovir
9. 33. Purines, pyrimidines, and glyoxalines. Part VIII. New syntheses of uracils and thymines
10. Synthesis of the carbocyclic analogs of uracil nucleosides
11. 4-(1,2,4-Triazol-1-yl)- and 4-(3-nitro-1,2,4-triazol-1-yl)-1-(?-D-2,3,5-tri-O-acetylarabinofuranosyl)pyrimidin-2(1H)-ones. Valuable intermediates in the synthesis of derivatives of 1-(?-D-arabinofuranosyl)cytosine (ara-C)