Altered expression of dopamine D2 receptor rnRNA splice variants in brain and pituitary of spontaneously hypertensive rats

Neuroscience Letters

Volumn 195, Issue 1, 1995, Pages 1-4

  Autelitano, Dominic J ^a   van den Buuse, Maarten ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Brain; Dopamine D2 receptors; Gene expression; Pituitary; Spontaneously hypertensive rat

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; MESSENGER RNA;

ADENOHYPOPHYSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; CORPUS STRIATUM; GENE EXPRESSION REGULATION; HYPERTENSION; HYPOPHYSIS INTERMEDIATE LOBE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RNA SPLICING; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMAL; AUTORADIOGRAPHY; BRAIN CHEMISTRY; COMPARATIVE STUDY; HYPERTENSION; IN VITRO; MALE; NEOSTRIATUM; PITUITARY GLAND; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T;

EID: 0029122947     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)11756-M     Document Type: Article

References (19)

1. Dopamine D2-receptor messenger RNA is differentially regulated by dopaminergic agents in rat anterior pituitary and neurointermediate pituitary
2. Cloning and expression of a rat D2 dopamine receptor cDNA
3. Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain
4. Altered behavioural response to a D-2 agonist, LY 141865, in SHR exhibiting biochemical and endocrine responses similar to those in normotensive rats
5. Alternative splicing directs the expression of two D2 dopamine receptor isoforms
6. Structural subtypes of the dopamine D2 receptor are functionally distinct: expression of the cloned D2A and D2B subtypes in a heterologous cell line
7. Dopamine receptor gene expression by enkephalin neurons in rat forebrain
8. Dopamine DI and D2 receptors in the caudate nucleus of spontaneously hypertensive rats and normotensive Wistar-Kyoto rats
9. Multiple D2 dopamine receptors produced by alternative splicing
10. Transcription mediated by a cAMP-responsive promoter element is reduced upon activation of dopamine D2 receptors
11. Preferential coupling between dopamine D2 receptors and G-proteins
12. Increased abundance of alternatively spliced forms of D2 dopamine receptor mRNA after denervation
13. A subtype
14. Distribution of dopamine D2 receptor mRNA splice variants in the rat by solution hybridization/protection assay
15. Differential coupling of dopaminergic D2 receptors expressed in different cell types
16. Brain dopamine depletion by lesions of the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat
17. Central effects of quinpirole on blood pressure of spontaneously hypertensive rats
18. Pharmacology of central dopaminergic modulation in hypertension
19. Brain dopamine D-2 receptor mechanisms in spontaneously hypertensive rats