Non-invasive measurement of human endothelium dependent arterial responses: Accuracy and reproducibility

Heart

Volumn 74, Issue 3, 1995, Pages 247-253

  Sorensen, Keld E ^a,c   Celermajer, David S ^a   Spiegelhalter, David J ^b   Georgakopoulos, Dimitri ^a   Robinson, Jacqui ^a   Thomas, Odette ^a   Deanfield, John E ^a  

^a Hospital for Sick Children ^*  (United Kingdom)

^b MRC BIOSTATISTICS UNIT   (United Kingdom)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERYL TRINITRATE;

ADULT; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; ENDOTHELIUM; FEMALE; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; SUBLINGUAL DRUG ADMINISTRATION; ULTRASOUND;

ADULT; ANALYSIS OF VARIANCE; ARTERIES; ARTERIOSCLEROSIS; COMPARATIVE STUDY; ENDOTHELIUM, VASCULAR; FEMALE; HUMAN; MALE; MIDDLE AGE; MODELS, STRUCTURAL; REGIONAL BLOOD FLOW; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0029117715     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.74.3.247     Document Type: Article

References (24)

1. Ross, R. The pathogenesis of atherosclerosis N EnglJ Med 1986 10.1056/NEJM198602203140806 314 488
2. Henderson, A.H. Endothelium in control Br Heart Y 1991 65 116
3. Ludmer, P.L.; Selwyn, A.P.; Shook, T.L. Paradoxical vasoconstriction induced by acethylcholine in atherosclerotic coronary arteries N Engl J Med 1986 10.1056/NEJM198610233151702 315 1046
4. Vita, J.A.; Treasure, C.B.; Nabel, E.G. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease Circulation 1990 10.1161/01.CIR.81.2.491 81 491
5. Celermajer, D.S.; Sorensen, K.E.; Georgakopoulos, D. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilatation in healthy young adults Circulation 1993 10.1161/01.CIR.88.5.2149 88 2149
6. Panza, J.A.; Quyyumi, A.A.; Callahan, T.S.; Epstein, S.E. Effect of antihypertensive treatment on endothelium-dependent vascular relaxation in patients with essential hypertension Y Am Coll Cardiol 1993 21 1 1 145
7. Zeiher, A.M.; Drexler, H.; Wollschlager, H.; Just, H. Modulation of coronary vasomotor tone in humans Circulation 1991 83 391
8. Mugge, A.; Heublin, B.; Kuhn, M. Impaired coronary dilator responses to substance P and impaired flowdependent dilator responses in heart transplant patients with graft vasculopathy Y Am Coll Cardiol 1993 10.1016/0735-1097(93)90732-G 21 163
9. Nabel, E.L.; Selwyn, A.P.; Ganz, P. Large coronary arteries in humans are responsive to changing flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis JAm Coll Cardiol 1990 10.1016/0735-1097(90)90584-C 16 349
10. Celermajer, D.S.; Sorensen, K.E.; Gooch, V.M. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis Lancet 1992 10.1016/0140-6736(92)93147-F 340 1111
11. Sorensen, K.E.; Celermajer, D.S.; Georgakopoulos, D. Impairment of endothelium-dependent dilatation is an early event in children with familial hypercholesterolemia, and is related to the Lp(a) level Clin Invest 1994 10.1172/JCI116983 93 50
12. Celermajer, D.S.; Sorensen, K.E.; Ryalls, M. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous parents Am Coil Cardiol 1993 10.1016/0735-1097(93)90203-D 22 854
13. Uehata, A.; Gerhard, M.D.; Meredith, I.T. Close relationship of endothelial dysfunction in coronary artery and brachial artery Circulation 1993 88 618
14. Lieberman, E.; Knab, S.; Creager, M. Nitric oxide mediates the vasodilator responses to flow in humans Circulation 1994 90 138
15. Vita, J.A.; Treasure, C.B.; Yeung, A.C. Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines Circulation 1992 10.1161/01.CIR.85.4.1390 85 1390
16. Treasure, C.B.; Klein, J.L.; Vita, J.A. Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels Circulatiwn 1993 10.1161/01.CIR.87.1.86 87 86
17. Vita, J.A.; Treasure, C.B.; Nabel, E.G. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease Circulation 1990 10.1161/01.CIR.81.2.491 81 491
18. Celermajer, D.S.; Cullen, S.; Deanfield, J.E. Impairment of endothelium-dependent pulmonary artery relaxation in children with congenital heart disease and abnormal pulmonary hemodynamics Circulation 1993 10.1161/01.CIR.87.2.440 87 440
19. Liao, J.K.; Bettmann, M.A.; Sandor, T. Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis Circ Res 1991 10.1161/01.RES.68.4.1027 68 1027
20. Spears, JR, Sandor; T, Als; A.V. Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms Circulation 1983 10.1161/01.CIR.68.2.453 68 453
21. Rubanyi, G.M.; Romero, C.; Vanhoutte, P.M. Flow-induced release of endothelium-derived relaxing factor Am Physiol 1986 250 1115
22. Pohl, U.; Holz, J.; Busse, R.; Bassenge, E. Crucial role of endothelium in the vasodilator response to increased flow in vivo Hypertension 1986 10.1161/01.HYP.8.1.37 8 37
23. Cox, D.A.; Vita, J.A.; Treasure, C.B. Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans Circulation 1989 10.1161/01.CIR.80.3.458 80 458
24. Cooke, J.P.; Singer, A.H.; Tsao, P. Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit Clin Invest 1992 10.1172/JCI115937 90 1168