Thermostabilization of live virus vaccines by heavy water (D2O)

Vaccine

Volumn 13, Issue 12, 1995, Pages 1058-1063

  Wu, Rong ^a   Georgescu, Maria Magdalena ^a   Delpeyroux, Francis ^a   Guillot, Sophie ^a   Balanant, Jean ^a   Simpson, Karl ^a   Crainic, Radu ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Heavy water (D2O); poliovirus; thermostability; vaccine; yellow fever

Indexed keywords

DEUTERIUM OXIDE; LIVE VACCINE; POLIOMYELITIS VACCINE; YELLOW FEVER VACCINE;

ARTICLE; POLIOMYELITIS; PRIORITY JOURNAL; THERMOSTABILITY; VACCINATION; WORLD HEALTH ORGANIZATION;

CELL LINE; DEUTERIUM OXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT; HUMAN; MAGNESIUM CHLORIDE; POLIOVIRUS VACCINE, ORAL; POLIOVIRUSES; SUPPORT, NON-U.S. GOV'T;

EID: 0029115185     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0264-410X(95)00068-C     Document Type: Article

References (24)

1. 2O) on the cell
2. 2O on the resistance of the procollagen to heat denaturation and to the collagenase action
3. 2O, and thermotolerance
4. Comparison of the stability of phycocyanins from thermophilic, mesophilic, psychrophilic and halophilic algae
5. Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine
6. Stable isotopes in clinical research: safety reaffirmed (editorial)
7. Transgenic mice susceptible to poliovirus
8. Thermodynamic and dynamic properties of water
9. Effects de l'eau lourde sur le développement du poliovirus en fonction de la temperature
10. Enteroviruses: polioviruses, coxsackieviruses, echoviruses and newer enteroviruses
11. 2-stabilized oral poliovaccine
12. Function of minor polypeptides in foot-and-mouth disease virus and poliovirus
13. Factors affecting the immunogenicity of oral polio vaccine in developing countries: review
14. Thermal inactivation of oral polio vaccine: contribution of RNA and protein inactivation
15. Oral poliovirus vaccine: history of its development and use and current challenge to eliminate poliomyelitis from the world
16. History of Sabin attenuated poliovirus oral live vaccine strains
17. Control of influence and poliomyelitis with killed virus vaccine
18. Water Structure
19. A mutation in the RNA polymerase of poliovirus type 1 contributes to attenuation in mice
20. Human serum cholesterol synthesis measured with the deuterium label
21. Cationic stabilization—a new property of enteroviruses
22. Global eradication of poliomyelitis by the year 2000
23. Global eradication of poliomyelitis by the year 2000
24. Requirements for poliomyelitis vaccine (oral)