Neuronal Activity and Neuropeptide Gene Transcription in the Brains of Immune‐Challenged Rats

Journal of Neuroendocrinology

Volumn 7, Issue 7, 1995, Pages 501-525

  Rivest, Serge ^a   Laflamme, Nathalie ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Corticotropin releasing factor; hypothalamic pituitary adrenal axis; immediate early genes; intronic probe technology; oxytocin; vasopressin

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; LIPOPOLYSACCHARIDE; MESSENGER RNA; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR INDUCIBLE PROTEIN B; NEUROPEPTIDE; OXYTOCIN; UNCLASSIFIED DRUG; VASOPRESSIN;

AMBIGUUS NUCLEUS; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; AREA POSTREMA; ARTICLE; BRAIN; BRAIN REGION; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS SYSTEM; HYPOTHALAMUS NUCLEUS; IMMEDIATE EARLY GENE; IMMUNOCYTOCHEMISTRY; IMMUNOSTIMULATION; IN SITU HYBRIDIZATION; LATERAL RETICULAR NUCLEUS; LOCUS CERULEUS; MALE; MEDIAN EMINENCE; NERVE CONDUCTION; NONHUMAN; ONCOGENE C FOS; PARABRACHIAL NUCLEUS; PREOPTIC AREA; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; SUPRAOPTIC NUCLEUS; TEGMENTUM; THALAMUS MIDLINE NUCLEUS;

ACUTE-PHASE REACTION; ANIMAL; BRAIN; GENES, IMMEDIATE-EARLY; HISTOCYTOCHEMISTRY; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNIZATION; IN SITU HYBRIDIZATION; MALE; NEURONS; NEUROPEPTIDES; PITUITARY-ADRENAL SYSTEM; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC;

EID: 0029113915     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.1995.tb00788.x     Document Type: Article

References (72)

1. Stress‐induced alteration of immune function
2. Interleukin‐I and its biologically related cytokines
3. Demonstration of interleukin‐1β in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultrastructural level
4. Increase IL‐6, IL‐1 and TNF levels in rat brain following traumatic lesion
5. Immobilization stress induces interleukin‐1β mRNA in the rat hypothalamus
6. Appearance of interleukin‐1 in macrophages and in ramified microglia in the brain of endotoxin‐treated rats: a pathway for the induction of non‐specific symptoms of sickness
7. Synthesis of interleukin‐1/endogenous pyrogen in the brain of endotoxin‐treated mice: a step in fever induction
8. A functional anatomical analysis of central pathways subserving the effects of interleukin‐1 on stress‐related neuroendocrine neurons
9. Differential effects of central and peripheral injection of interleukin‐1β on brain c‐fos expression and neuroendocrine functions
10. Stress and interleukin‐1β‐induced activation of c‐fos, NGFI‐B and CRF gene expression in the hypothalamic PVN: Comparison between Sprague‐Dawley, Fisher‐344 and Lewis rats
11. Systemic interleukin‐1 induces early and late patterns of C‐fos mRNA expression in brain
12. Interleukin‐1 stimulates the secretion of hypothalamic corticotropin‐releasing factor
13. Corticotropin‐releasing factor producing neurons in the rat activated by interleukin‐1
14. Intrahypothalamic infusion of interleukin‐1β increases the release of corticotropin‐releasing hormone (CRH 41) and adrenocorticotropic hormone (ACTH) in free‐moving rats bearing a push‐pull cannula in the median eminence
15. Interleukin‐1 stimulates corticotropin‐releasing factor gene expression in rat hypothalamus
16. Interleukin‐1 and ‐6 stimulate the release of corticotropin‐releasing hormone‐41 from rat hypothalamus in vitro via the eicosanoid cyclooxygenase pathway
17. Interleukin‐1 directly stimulates the release of corticotrophin‐releasing factor from rat hypothalamus
18. Stress and antibody response in rats
19. Induction of interleukin‐1β mRNA in adult rat brain
20. Presence of cytokines in the hypothalamic‐pituitary axis
21. Interleukin‐1β production in vivo and in vitro in rats and mice measured using specific immuno‐radiometric assays
22. Biochemistry of endotoxins
23. Secretory products of macrophages
24. Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus
25. Differential induction of c‐fos immunoreactivity in hypothalamus and brain stem nuclei following central and peripheral administration of endotoxin
26. Endotoxin‐induced corticotropin‐releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin‐1
27. Mechanisms mediating the effects of cytokines in neuroendocrine functions in the rat
28. A complete loop between the immune system and neuroendocrine systems
29. The role of CRF and interleukin‐1 in the regulation of neurons controlling reproductive functions
30. Molecular mechanisms and neural pathways mediating the influence of interleukin‐1 on the activity of neuroendocrine CRF motoneurons in the rat
31. Centrally injected interleukin‐1β inhibits the hypothalamic LHRH secretion and circulating LH levels via prostaglandins in rats
32. Roles of interleukin‐1α and β in endotoxin‐induced suppression of plasma gonadotropin levels in rats
33. Stimulus‐transcription coupling in the nervous system: Involvement of the inductible protooncogenes fos and jun
34. Transsynaptic control of gene expression
35. The regulation and function of c‐fos and other immediate early genes in the nervous system
36. A comparison of two immediate early genes, c‐fos and NGFI‐B, as markers for functional activation in stress‐related neuroendocrine pathways
37. Luteinizing hormone‐releasing hormone express Fos protein during the proestrus surge of luteinizing hormone
38. Interleukin‐1β inhibits the endogenous expression of the early gene c‐fos located within the nucleus of LHRH neurons and interferes with hypothalamic LHRH release during proestrus in the rat
39. The NGFI‐B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: Genomic structure and expression in rat brain after seizure induction
40. Corticotropin‐releasing factor activates c‐fos, NGFI‐B and CRF gene expression within the paraventricular nucleus of the rat hypothalamus
41. Identification of a cyclic adenosine monophosphate‐responsive element in the rat corticotropin‐releasing hormone gene
42. Cloning and distribution of expression of the rat corticotropin‐releasing factor (CRF) gene
43. Stress‐induced transcriptional activation of the corticotropin‐releasing factor gene precedes immediate‐early‐genes responses in the paraventricular nucleus
44. Expression of a large family of POU‐domain regulatory genes in mammalian brain development
45. Identification and characterization of a 3′,5′‐cyclic adenosine monophosphate‐responsive element in the human corticotropin‐releasing hormone gene promoter
46. Early induction of c‐fos precedes increased expression of corticotropin‐releasing factor messenger ribonucleic acid in the paraventricular nucleus after immobilization stress
47. Differential regulation of corticotropin‐releasing factor mRNA in rat brain regions by glucocorticoids and stress
48. Neural and biochemical mediators of endotoxin and stress‐induced c‐fos expression in the rat brain
49. The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
50. The CRH motoneuron: Differential peptide regulation in neurons with possible synaptic. paracrine, and endocrine outputs
51. Interleukin‐1 stimulates ACTH release by an indirect mechanisms which requires endogenous corticotropin‐releasing factor
52. Tumor necrosis factor‐alpha is a potent ACTH secretagogue: comparison to interleukin‐1β
53. The adrenocorticotropin response to interleukin‐1β installed into the rat median eminence depends on the local release of catecholamines
54. The organization of forebrain afferents to the paraventricular and supraoptic nuclei of the rat
55. Regional and cellular codistribution of interleukin‐1β and nerve growth factor mRNA in the adult rat brain
56. Stress and the single cytokine: interleukin modulation of the pituitary‐adrenal axis
57. Production of prostaglandins E and an interleukin‐1 like factor by cultured astrocytes and C glioma cells
58. Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice
59. The chronic intracerebro‐ventricular infusion of interleukin‐1β alters the activity of the hypothalamic‐pituitary‐gonadal axis of cycling rats. 1. Effect on LHRH and gonadotropin biosynthesis and secretion
60. Mediation by corticotropin‐releasing factor (CRF) of adenohypophysial hormone secretion
61. Oxytocin as well as vasopressin potentiate ovine CRF in vitro.
62. Paradoxical responses of hypothalamic corticotropin‐releasing factor (CRF) messenger ribonucleic acid (mRNA) and CRF‐41 peptide and adenohypophysial proopimelanocortin mRNA during chronic inflammatory stress
63. Ultrastructural demonstration of oxytocin and vasopressin release sites in the neural lobe and median eminence of the rat by tannic acid and immunogold methods
64. Corticotrophin‐releasing peptides in rat hypophysial portal blood after paraventricular lesions: a marked reduction in the concentration of corticotrophin‐releasing factor‐41, but no change in vasopressin
65. The functional neuroanatomy of corticotropin‐releasing factor
66. Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat
67. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radio‐labeled single‐stranded RNA probes
68. Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene
69. Rapid regulation of corticotropin‐releasing hormone gene transcription in vivo.
70. In situ hybridization: a methodological guide