Molecular modeling studies of the artemisinin (qinghaosu)-hemin interaction: Docking between the antimalarial agent and its putative receptor

Journal of Molecular Graphics

Volumn 13, Issue 4, 1995, Pages 215-222

  Shukla, Kanhiya L ^a   Gund, Tamara M ^a   Meshnick, Steven R ^b  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

antimalarial; artemisinin; docking; hemin; malaria; molecular modeling; qinghaosu

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISIN DERIVATIVE; ARTEMISININ; ENDOPEROXIDE; HEMIN; IRON;

ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; MOLECULAR MODEL; PLASMODIUM; PRIORITY JOURNAL;

ANTIMALARIALS; COMPARATIVE STUDY; COMPUTER SIMULATION; DRUG DESIGN; DRUGS, CHINESE HERBAL; HEMIN; IRON; MODELS, MOLECULAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SESQUITERPENES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029112920     PISSN: 02637855     EISSN: None     Source Type: Journal    
DOI: 10.1016/0263-7855(94)00001-9     Document Type: Article

References (25)

1. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases
2. The chemistry, pharmacology, and clinical applications of qinghaosu (Artemisinin) and its derivatives
3. Chemical studies on qinghaosu (artemisine)
4. The interaction of artemisinin with malarial hemozoin.
5. Alkylation of human albumin by the antimalarial artemisinin
6. Ann. Trop. Med. Hyg