The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue

Nature

Volumn 375, Issue 6532, 1995, Pages 554-560

  Nassar, Nicolas ^a   Horn, Gudrun ^a   Herrmann, Christian A ^a   Scherer, Anna ^a,b   McCormick, Frank ^a,c   Wittinghofer, Alfred ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^c ONYX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GTP BINDING PROTEINS; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANYLYLIMIDODIPHOSPHATE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASES; PROTO ONCOGENE PROTEINS; PROTO ONCOGENE PROTEINS C RAF; RAF PROTEIN; RAP GTP BINDING PROTEINS; RAP PROTEIN; RECOMBINANT PROTEIN; RAS PROTEIN; UBIQUITIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; COMPUTER GRAPHICS; ESCHERICHIA COLI; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; GUANYLYL IMIDODIPHOSPHATE; HUMAN; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RAP GTP-BINDING PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 0029107760     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/375554a0     Document Type: Article

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