Carbon—Hydrogen Bonds of DNA Sugar Units as Targets for Chemical Nucleases and Drugs

Angewandte Chemie International Edition in English

Volumn 34, Issue 7, 1995, Pages 746-769

  Pratviel, Geneviève ^a   Bernadou, Jean ^a   Meunier, Bernard ^a  

^a CNRS   (France)

Author keywords

bleomycin; DNA cleavage; enediynes; transition metal complexes

Indexed keywords

EID: 0029103994     PISSN: 05700833     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.199507461     Document Type: Review

References (376)

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2. Biochemie des oxidativen Stress
3. Biological consequences associated with DNA oxidation mediated by singlet oxygen.
4. Phosphorus-32 postlabeling measurement of adenine N-1-oxide in cellular DNA exposed to hydrogen peroxide
5. Oxidative degradation of nucleic acids
6. Mechanisms of bleomycin-induced DNA degradation
7. Chemistry and biology of natural and designed enediynes.
8. Specific abstraction of the 5'S- and 4'-deoxyribosyl hydrogen atoms from DNA by calicheamicin .gamma.1I
9. Nuclease activity of 1,10-phenanthroline-copper ion
10. Chemical nucleases
11. Sequence specificity of the deoxyribonuclease activity of 1,10-phenanthroline-copper ion
12. Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.
13. Der Kampf um Calicheamicin γ1I
14. Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes.
15. Esperamicins, a class of potent antitumor antibiotics: mechanism of action.
16. DNA strand scission by bleomycin: catalytic cleavage and strand selectivity
17. Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA.
18. Oxygen Activation by Cytochrome P-4501
19. High-valent iron-porphyrin complexes related to peroxidase and cytochrome P-450
20. Bleomycin as an oxene transferase. Catalytic oxygen transfer to olefins
21. Synthesis of bleomycin A5 oligonucleotide derivatives and site-specific cleavage of the DNA target
22. Interactions of T7 RNA polymerase with T7 late promoters measured by footprinting with methidiumpropyl-EDTA-iron(II)
23. The unusual conformation adopted by the adenine tracts in kinetoplast DNA
24. Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.
25. Sequence-specific recognition of B DNA by bis(EDTA-distamycin)fumaramide
26. A synthetic peptide binds 16 base pairs of A,T double helical DNA
27. Nonenzymatic sequence-specific cleavage of single-stranded DNA.
28. Double strand cleavage of genomic DNA at a single site by triple helix formation
29. Cooperative site specific binding of oligonucleotides to duplex DNA
30. Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation.
31. Structure of monomeric hydrated manganese(III) tetra(4-N-methylpyridyl)porphyrin pentachloride
32. PHOTOCLEAVAGE OF DNA IN THE PRESENCE OF SYNTHETIC WATER-SOLUBLE PORPHYRINS
33. Structure—activity relationships for DNA photocleavage by cationic porphyrins
34. Interaction of Porphyrins and Metalloporphyrins with Nucleic Acids
35. The Dependence of the Surface Electrostatic Potential of B-DNA on Environmental Factors
36. On the chemical nature of DNA and RNA modification by a hemin model system
37. Selektive Spaltung einer 35mer-Einzelstrang-DNA, die den Startcodon des TAT-Gens von HIV-1 enthält, durch ein maßgeschneidertes kationisches Manganporphyrin-Konjugat
38. Probing Nucleic Acids with Transition Metal Complexes
39. Photophysics of ruthenium complexes bound to double helical DNA
40. Efficient electrocatalytic and stoichiometric oxidative cleavage of DNA by oxoruthenium(IV)
41. Studies of electrocatalytic DNA cleavage by oxoruthenium(IV). X-ray crystal structure of [Ru(tpy)(tmen)OH2](ClO4)2 (tmen = N,N,N',N'-tetramethylethylenediamine, tpy = 2,2',2''-terpyridine)
42. Evidence for altered DNA conformations in the simian virus 40 genome: site-specific DNA cleavage by the chiral complex lambda-tris(4,7-diphenyl-1,10-phenanthroline)cobalt(III).
43. Trimethylenemethane. Experimental demonstration that the triplet state is the ground state
44. NMR evidence for specific intercalation of .DELTA.-rh(phen)2.phi.3+ in [d(GTCGAC)2]
45. Furfural als Indikator einer DNA-Spaltung durch Hydroxylierung des C5′-Kohlenstoffatoms von Desoxyribose
46. Importance of minor-groove contacts for the recognition of DNA by the binding domain of Hin recombinase
47. Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the Hix site
48. Iron(II) Bleomycin-Mediated Degradation of a DNA-RNA Heteroduplex
49. Correlations of Crystal Structures of DNA Oligonucleotides with Enantioselective Recognition by Rh(phen)2phi3+: Probes of DNA Propeller Twisting in Solution