Cell cycle arrest in response to DNA damage: lessons from yeast

Mutation Research-DNA Repair

Volumn 337, Issue 2, 1995, Pages 73-84

  Siede, Wolfram ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cell cycle regulation; Checkpoint; DNA damage; DNA repair; Yeast

Indexed keywords

CELL CYCLE; CHROMOSOME BREAKAGE; DNA DAMAGE; DNA REPAIR; NONHUMAN; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; YEAST;

CELL CYCLE; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; RIBONUCLEOTIDE REDUCTASES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; TRANSCRIPTION FACTORS;

EID: 0029101953     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/0921-8777(95)00023-D     Document Type: Short Survey

References (100)

1. DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe
2. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
3. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage induced transcription in yeast
4. cdc28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae
5. Protein kinases and the response to DNA damage
6. The nuclear serine/threonine protein kinase DNA-PK
7. Induction of the genes RAD54 and RNR2 by various DNA damaging agents in Saccharomyces cerevisiae
8. Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid
9. Human p53 inhibits growth in Schizosaccharomyces pombe
10. A chromosome breakage assay to monitor mitotic forces in budding yeast
11. Preferential repair in Saccharomyces cerevisiae
12. The relevance of the nuclear division cycle to radiosensitivity in yeast
13. DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae
14. 1 cell cycle checkpoint pathway and ataxia-telangiectasia
15. Radiation checkpoints in model systems
16. Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics
17. A p53-dependent mouse spindle checkpoint
18. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
19. 1 arrest and apoptosis
20. DNA damage induction of ribonucleotide reductase
21. Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase
22. DNA damage and cell cycle regulation of ribonucleotide reductase
23. Fission yeast genes involved in coupling mitosis to completion of DNA replication
24. Budding and division delay in diploid yeast after irradiation
25. Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
26. Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
27. A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
28. Apoptosis in cancer therapy: crossing the threshold
29. Transcription and nucleotide excision repair -reflections, considerations and recent biochemical insights
30. DNA repair comes of age
31. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
32. Defects in a cell cycle checkpoint may be responsible for the genetic instability of cancer cells
33. Cell cycle control and cancer
34. Checkpoints: controls that ensure the order of cell cycle events
35. Nucleotide excision repair II: From yeast to mammals
36. Keeping mitosis in check
37. X-ray sensitive mutants of Chinese hamster ovary cell line: radio-sensitivity of DNA synthesis
38. 1/S checkpoint?
39. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia
40. An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae
41. Cell cycle control, DNA repair and initiation of carcinogenesis
42. Cell cycle control and cancer chemotherapy
43. Wild-type p53 is a cell cycle checkpoint determinant following irradiation
44. Arrest of the mitotic cell cycle and of meiosis in Saccharomyces cerevisiae by MMS
45. Inhibition of DNA replication by ionizing radiation is mediated by a trans-acting factor
46. p53, guardian of the genome
47. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
48. A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest
49. Exercising self-restraint: discouraging illicit acts of S and M in eukaryotes
50. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
51. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells
52. Dicing with death: dissecting the components of the apoptosis machinery
53. A kinase from fission yeast responsible for blocking mitosis in S phase
54. Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective
55. Cell checkpoint and radiosensitivity
56. Creative blocks: cell-cycle checkpoints and feedback controls
57. DNA polymerase ε links the DNA replication machinery to the S phase checkpoint
58. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways
59. Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae
60. An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells
61. Radiosensitivity in Ataxia Telangiectasia: a new explanation
62. 2 checkpoint function in cells from individuals with familial cancer syndromes
63. The G1/S cell-cycle checkpoint in eukaryotic cells
64. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle
65. Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast
66. Activation of a yeast replication origin near a double-stranded DNA break
67. Checkpoint controls in Schizosaccharomyces pombe: rad1
68. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor
69. Loss of a yeast telomere: arrest, recovery, and chromosome loss
70. A single ataxia telangiectasia gene with a product similar to PI-3 kinase
71. Mammalian p53 can function as a transcription factor in yeast
72. Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage
73. SIC1 controls the G1 to S transition in S. cerevisiae
74. Feedback controls and G2 checkpoints: fission yeast as a model system
75. RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae
76. 1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents
77. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
78. cdc2-activating kinase
79. cdc28
80. Differential repair of UV damage in rad mutants of Saccharomyces cerevisiae: a possible function of G2 arrest upon UV irradiation
81. Differential repair of UV damage in Saccharomyces cerevisiae is cell cycle dependent
82. Retraction: Differential repair of UV damage in Saccharomyces cerevisiae is cell cycle dependent
83. Stage-specific effects of X-irradiation on yeast meiosis
84. Genomic instability and cancer
85. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
86. DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase ε and is influenced by DNA polymerases α and δ in Saccharomyces cerevisiae
87. A RAD9-dependent checkpoint blocks meiosis of cdc13 yeast cells
88. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
89. Characterization of the RAD9 gene of Saccharomyces cerevisiae and evidence that it acts posttranslationally in cell cycle arrest after DNA damage
90. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
91. Cell cycle checkpoints, genetic instability and cancer
92. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
93. Retardation of cell cycle progression in yeast cells recovering from DNA damage: a study at the single cell level
94. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
95. Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
96. SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase
97. Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae
98. DUN1 encodes a protein kinase that controls the DNA damage response in yeast