Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

Journal of Medicinal Chemistry

Volumn 38, Issue 17, 1995, Pages 3193-3196

  Palmer, James T ^a   Rasnick, David ^a   Klaus, Jeffrey L ^a   Brömme, Dieter ^a  

^a Khepri Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CATHEPSIN B; CATHEPSIN L; CATHEPSIN O2; CATHEPSIN S; CRUZIPAIN; CYSTEINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VINYL SULFONE DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; INHIBITION KINETICS; PROTEINASE INHIBITION;

AMINO ACID SEQUENCE; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; KINETICS; MOLECULAR SEQUENCE DATA; SULFONES;

EID: 0029099619     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00017a002     Document Type: Article

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