A model for the study of wounds in normal elderly adults and patients with peripheral vascular disease or diabetes mellitus

Journal of Surgical Research

Volumn 59, Issue 3, 1995, Pages 349-360

  Olerud, John E ^a   Odland, George F ^b   Burgess, Ernest M ^c   Wyss, Craig R ^d   Fisher, Lloyd D ^b   Matsen, Frederick A ^d  

^a Departments of Medicine ^*  (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Departments of Orthopoedics ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARM; ARTICLE; CONTROLLED STUDY; DERMIS; DIABETES MELLITUS; EPIDERMIS; HUMAN; HUMAN TISSUE; LEG; MACROPHAGE; MAJOR CLINICAL STUDY; NEUTROPHIL; OXYGEN TENSION; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; SKIN INJURY; TRANSCUTANEOUS OXYGEN MONITORING; WOUND HEALING;

AGED; ARM INJURIES; BLOOD GAS MONITORING, TRANSCUTANEOUS; CELL COUNT; COMPARATIVE STUDY; DIABETES MELLITUS; DIABETIC ANGIOPATHIES; EPIDERMIS; FIBROBLASTS; HUMAN; LEG INJURIES; MIDDLE AGE; MONOCYTES; NEUTROPHILS; PERIPHERAL VASCULAR DISEASES; SUPPORT, U.S. GOV'T, NON-P.H.S.; TIME FACTORS; WOUND HEALING;

EID: 0029098881     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1006/jsre.1995.1175     Document Type: Article

References (23)

1. Woodley, D. T., and Kim, Y. H. A double-blind comparison of adhesive bandages with the use of uniform suction blister wounds. Arch. Dermatol. 128:1354, 1992.
2. Svedman, P., Svedman, C., and Njalsson, T. Epithelialization and blood flow in suction blister wounds on healthy volunteers. J. Invest. Surg. 4:175, 1991.
3. Dvonch, V. M., Murphey, R. J., Matsuoka, J., and Grotendorst, G. R. Changes in growth factor levels in human wound fluid. Surgery 112: 18, 1992.
4. Lorenz, H. P., Longaker, M. T., Perkocha, L. A., Jennings, R. W., Harrison, M. R., and Adzick, N. S. Scar less wound repair: A human fetal skin model. Development 114: 253, 1992.
5. Reuterdahl, C., Sundberg, C., Rubin, K., Funa, K., and Gerdin, B. Tissue localization of (3 receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans. J. Clin. Invest. 91: 2065, 1993.
6. Steed, D. L., Goslen, J. B., Holloway, G. A., Malone, J. M., Bunt, T. J., and Webster, M. W. Randomized perspective double-blind trial in healing chronic diabetic foot ulcers. CT-102 activated platelet supernatant, topical versus placebo. Diabetes Care 15: 1598, 1992.
7. Odland, G. F., and Ross, R. Human wound repair. L Epidermal regeneration. J. Cell Biol. 39:135, 1968.
8. Ross, R., and Odland, G. F. Human wound repair. II. Inflammatory cell, epithelial mesenchymal interrelation and fibrogenesis. J. Cell Biol. 39:152, 1968.
9. Olerud, J. E., Gown, A. M., Bickenbach, J., Dale, B., and Odland, G. F. An assessment of human epidermal repair in elderly normal subjects using immunohistochemical methods. J. Invest. Dermatol. 90: 845, 1988.
10. Raugi, G. J., Olerud, J. E., and Gown, A. M. Thrombospondin in early human wound tissue. J. Invest. Dermatol. 89: 551, 1987.
11. Ansel, J. C., Tiesman, J. P., Olerud, J. E., Krueger, J. G., Krane, J. F., Tara, D. C., Shipley, G. D., Gilbertson, D., Usui, M. L., and Hart, C. E. Human keratinocytes are a major source of cutaneous platelet-derived growth factor. J. Clin. Invest. 92: 671, 1993.
12. Saarialho-Kere, U. K., Kovacs, S. O., Pentland, A. P., Olerud, J. E., Welgus, H. G., and Parks, W. C. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J. Clin. Invest. 92: 2858, 1993.
13. Olerud, J. E., Pecoraro, R. E., Burgess, E. M., McKnight, B., Wyss, C. R., Reiber, G. E., and Matsen, F. A. Reliability of trans-cutaneous oxygen tension (TcP02) measurements in elderly normal subjects. Scand. J. Clin. Lab. Invest. 47: 535, 1987.
14. Karnovsky, M. J. A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J. Cell Biol. 27: 137A, 1965.
15. Luft, J. H. Improvements in epoxy resin embedding methods. J. Biophys. Biochem. Cytol. 9: 409, 1961.
16. Richardson, K. C., Jarrett, L., and Finke, E. H. Embedding epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 35: 313, 1960.
17. Pecoraro, R. E., Reiber, G. E., and Burgess, E. M. Pathways to diabetic limb amputation. Basis for prevention. Diabetes Care 13:513, 1990.
18. Pecoraro, R. E., Ahroni, J. H., Boyko, E. J., and Stensel, V. L. Chronology and determinants of tissue repair in diabetic lower-extremity ulcers. Diabetes 40: 1305, 1991.
19. Reiber, G. E., Pecoraro, R. E., and Koepsell, T. D, Risk factors for amputation in patients with diabetes mellitus. Ann. Intern. Med. 117:97, 1992.
20. Wyss, C. R., and Matsen, F. A. III. Transcutaneous oxygen tension measurements on limbs of diabetic and nondiabetic patients with peripheral vascular disease. Surgery 95: 339, 1984.
21. Brownlee, M., Vlassara, H., and Cerami, A. Nonenzymatic gly-cosylation and the pathogenesis of diabetic complications. Ann. Intern. Med. 101: 527, 1984.
22. Kelly, S. B., Olerud, J. E., Witztum, J. L., Curtiss, L. K., Gown, A. M., and Odland, G, F. A method for localizing the early products of nonenzymatic glycosylation in fixed tissue. J. Invest. Dermatol 93: 327, 1989.
23. Goodson III, W. H., and Hunt, T. K. Development of a new miniature method for the study of wound healing in human subjects. J. Surg. Res. 33: 394, 1982.