The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 17, 1995, Pages 7839-7843

  Schwecke, Torsten ^a   Aparicio, Jesús F ^a   Molnár, István ^a   König, Ariane ^a   Khaw, Lake Ee ^a   Haydock, Stephen F ^a   Oliynyk, Markiyan ^a,b   Caffrey, Patrick ^a   Cortés, Jesús ^a   Lester, John B ^a   Böhm, Günter A ^a   Staunton, James ^a   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IVAN FRANKO NATIONAL UNIVERSITY OF LVIV   (Ukraine)

Author keywords

FK506; peptide synthetase; polyketide synthase; Streptomyces

Indexed keywords

RAPAMYCIN; TACROLIMUS;

ANIMAL CELL; ARTICLE; DRUG SYNTHESIS; GENE CLUSTER; GENE EXPRESSION; IMMUNE DEFICIENCY; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN BINDING; STREPTOMYCES HYGROSCOPICUS;

ACYLTRANSFERASES; CLONING, MOLECULAR; COSMIDS; DNA, BACTERIAL; ESCHERICHIA COLI; GENE LIBRARY; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; PLASMIDS; POLYENES; SIROLIMUS; STREPTOMYCES; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; STREPTOMYCES; STREPTOMYCES HYGROSCOPICUS;

EID: 0029098323     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.17.7839     Document Type: Article

References (37)