Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers

Blood

Volumn 86, Issue 7, 1995, Pages 2481-2487

  Macho, Antonio ^a   Castedo, Maria ^a   Marchetti, Philippe ^a   Aguilar, José J ^a   Decaudin, Didier ^a   Zamzami, Naoufal ^a   Girard, Pierre M ^a   Uriel, José ^a   Kroemer, Guido ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE ORANGE; DNA FRAGMENT; DYE; ETHIDIUM; FLUOROCHROME; ROTENONE; ZIDOVUDINE;

ADULT; ARTICLE; CELL CULTURE; CELL ISOLATION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOFLUOROMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MITOCHONDRION; MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029095014     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v86.7.2481.bloodjournal8672481     Document Type: Article

References (34)

1. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239, 1972
2. Willie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555, 1980
3. Meyaard L, Otto SA, Jonker RR, Mijnster MJ, Keet RPM, Miedema F: Programmed cell death in HIV-I infection. Science 257:217, 1992
4. Surh CD, Sprent J: T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100, 1994
5. Kawabe Y, Ochi A: Programmed cell death and extrathymic reduction of Vβ8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature 349:245, 1991
6. Johnston JB, Lee K, Verburg L, Blondal J, Mowat MRA, Israels LG, Begleiter A: Induction of apoptosis in CD4+ prolymphocytic leukemia by deoxuadenosine and 2′-deoxyformycin. Leuk Res 16:781, 1992
7. Gonzalo JA, González-García A, Martínez-A C, Kroemer G: Glucocorticoid-mediated control of the clonal deletion and activation of peripheral T cells in vivo. J Exp Med 177:1239, 1993
8. Kaufmann Y, Many A, Rechavi G, Mor O, Biniaminov M, Rosenthal E, Levanon M, Davidsohn J, Aizman I, Mark Z, Broksimoni F, Ramot B: Lymphoma with recurrent cycles of spontaneous remission and relapse - Possible role of apoptosis. N Engl J Med 332:507, 1995
9. Huang L, Soldevila G, Leeker M, Flavell R, Crispe IN: The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo. Immunity 1:741, 1994
10. Savill J, Fadok V, Henson P, Haslett C: Phagocyte recognition of cells undergoing apoptosis. Immunol Today 14:131, 1993
11. Groux H, Torpier G, Monté D, Mouton Y, Capron A, Ameisen JC: Activation-induced death by apoptotis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med 175:331, 1992
12. Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssière J-L, Petit PX, Kroemer G: Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 181:1661, 1995
13. Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G: Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 182:367, 1995
14. Petit PX, LeCouer H, Zorn E, Dauguet C, Mignotte B, Gougeon ML: Alterations of mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 130:157, 1995
15. Jacobson MD, Burne JF, Raff MC: Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J 13:1899, 1994
16. Newmeyer DD, Farschon DM, Reed JC: Cell-free apoptosis in xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 79:353, 1994
17. Kroemer G, Petit PX, Zamzami N, Vayssière J-L, Mignotte B: The biochemistry of apoptosis. FASEB J 1995 (in press)
18. Rothe G, Valet G: Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J Leukoc Biol 47:440, 1990
19. Petit PX, O'Connor JE, Grunwald D, Brown SC: Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications. Eur J Biochem 194:389, 1990
20. Petit JM, Maftah A, Ratinaud MH, Julien R: 10 N-nonyclacridine orange interacts with cardiolipin and allows for the quantification of phospholipids in isolated mitochondria. Eur J Biochem 209:267, 1992
21. Hockenbery DM, Oltvai ZN, Yin X-M, Milliman CL, Korsmeyer SJ: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241, 1993
22. Koopman G, Reutelingsperger CPM, Kuijten GAM, Keehnen RMJ, Pals ST, van Oers MHJ: Annexin V for flow cytometry detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415, 1994
23. Gunter TE, Pfeiffer DR: Mechanisms by which mitochondrial transport calcium. Am J Physiol 258:C755, 1990
24. Meyaard L, Schuitemaker H, Miedema F: Programmed death of T cells in HIV-1 infection: No correlation with progression to disease. J Clin Invest 93:982, 1994
25. Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM: Exposure of phophatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207, 1992
26. Danave IR, Tiffany-Castiglioni E, Zenger E, Barhoumi R, Burghardt RC, Collisson EW: Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential. J Virol 68:6745, 1994
27. Sandstrom PA, Mannie MD, Buttke TM: Inhibition of activation-induced death in a T cell hybridoma by thiol antioxidants - Oxidative stress as a mediator of apoptosis. J Leukoc Biol 55:221, 1994
28. Somasundaran M, Zapp ML, Beattie LK, Pang L, Byron KS, Bassell GJ, Sullivan JL, Singer RH: Localization of HIV RNA in mitochondria of infected cells: Potential role in cytopathogenicity. J Cell Biol 126:1353, 1994
29. Sandstrom PA, Tebbey PW, Vancleaven S, Buttke TM: Lipid hydroperoxides induce apoptosis in T-cells displaying a HIV-associated glutathione peroxidase deficiency. J Biol Chem 2:798, 1994
30. Westendorp MO, Shatrov VA, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Droge W, Lehrmann V: HIV-1 Tat potentiates TNF-induced NF-kB activation and cytotoxicity by altering the cellular redox state. EMBO J 14:546, 1995
31. Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, Deutsch P, Lifson JD, Bonhoeffer S, Nowak MA, Hahn BA, Saag MS, Shaw GM: Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373:117, 1995
32. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123, 1995
33. Banda NK, Bernier J, Kurahara DK, Kurrle R, Haigwood N, Sékaly R-P, Finkel TH: Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med 176:1099, 1992
34. Oyaizu N, McCloskey TW, Than S, Hu R, Kalyanaraman VS, Pahwa S: Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion. Blood 84:2622, 1994