Chemical Denaturation of Ovalbumin Abrogates the Induction of Oral Tolerance of Specific IgG Antibody and DTH Responses in Mice

Scandinavian Journal of Immunology

Volumn 42, Issue 3, 1995, Pages 297-304

  PENG, H J ^a   CHANG, Z N ^a   HAN, S H ^a   WON, M H ^a   HUANG, B T ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMINOID; IMMUNOGLOBULIN G; OVALBUMIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PURIFICATION;

ADMINISTRATION, ORAL; ALKYLATION; ANIMAL; GAMMA-GLOBULINS; HYPERSENSITIVITY, DELAYED; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; INTESTINAL ABSORPTION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; OVALBUMIN; PROTEIN DENATURATION; SERUM ALBUMIN, BOVINE; SUPPORT, NON-U.S. GOV'T; UREA;

EID: 0029094536     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.1995.tb03659.x     Document Type: Article

References (37)

1. Systemic tolerance and secretary immunity after oral immunization
2. The regulation of immune responses to dietary protein antigens
3. Immunological responses to fed protein antigens in mice. IV. Effects of stimulating the reticuloendo‐thelial system on oral tolerance and intestinal immunity to ovalbumin
4. Modulation of intestinal and systemic immune responses to a fed protein antigen in mice
5. Failure to induce oral tolerance to a protein antigen in neonatal mice can be corrected by transfer of adult spleen cells
6. Could specific oral tolerance be a therapy for autoimmune disease
7. Double‐blind pilot trial of oral tolerance with myelin antigens in multiple sclerosis
8. Suppression of type II collagen‐induced arthritis by intragastric administration of soluble type II collagen
9. Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy
10. Inhibition of specific immune responses by feeding protein antigens. II. Effects of prior passive and active immunization
11. Abrogation by subsequent feeding of antibody response, including IgE, in parenterally immunized mice
12. Feeding of antigen reduces antigen‐binding activity and blunts the secondary response of actively immunized rats
13. Suppression of an established DTH response to ovalbumin in mice by feeding antigen after immunization
14. The kinetics of oral hyposensitization to a protein antigen are determined by immune status and the timing, dose and frequency of antigen administration
15. Reaginic antibody formation in the mouse. VI. Suppression of IgE and IgG abtibody responses to ovalbumin following the administration of high dose ureadenatured antigen
16. Antigen recognition by T cells. II. Intravenous administration of native or denatued ovalbumin results in tolerance to both forms of the antigens
17. The role of antigen recognition and suppressor cells in mice with oral tolerance to ovalbumin
18. Oral tolerance to ovalbumin in mice: studies of chemically modified and “biologically filtered” antigen
19. The generation of a tolerogen after the ingestion of ovalbumin is time‐dependent and unrelated to serum levels of immunoreactive antigen
20. Studies on the specificity of antibodies to ovalbumin in normal human serum: technical considerations in the use of ELISA methods
21. Immunologic unresponsiveness after gastric administration of human Γ‐globulin: antigen require‐ments and cellular parameters
22. Aberrant tolerance induction with cationic antigens
23. Suppressor T cells for IgE and IgG in Peyer's patches of mice made tolerant by the oral administration of ovalbumin
24. Enterically induced immunological tolerance. I. Induction of suppressor T lymphocytes by intragastric administration of soluble proteins
25. In vivo tolerization of Thl lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression
26. Antigen processing at the molecular level
27. Pathways of viral antigen processing and presentation to CTL: defined by the mode of virus entry
28. Antigen recognition by H‐2‐restricted T cells. I. Cell‐free antigen processing
29. Reduction of disulfide bonds within lysosomes is a key step in antigen processing
30. Antigen conformation determines processing requirements for T‐cell activation
31. Passage of undegraded dietary antigen into the blood of healthy adults. Further characterization of the kinetics of uptake and the size distribution of the antigen
32. Pathophysiology of intestinal uptake and absorption of antigens in food allergy
33. Clinical and Immunological effects of oral immunotherapy with a standardised birch pollen extract
34. A double‐blind, placebocontrolled trial by the subllngual route of immunotherapy with a standardized grass pollen extract
35. A review of controversial techniques employed in allergy
36. Standards of practice—our responsibility