Molecular characterization of a common binding site for small molecules within the transmembrane domain of G-protein coupled receptors

Journal of Pharmacological and Toxicological Methods

Volumn 33, Issue 4, 1995, Pages 179-185

  Cascieri, Margaret A ^a   Fong, Tung Ming ^a   Strader, Catherine D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(2 BENZHYDRYL 2 DIMETHYLAMINOETHYL) 3,5 BIS(TRIFLUOROMETHYLBENZYL) ETHER; 2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; 2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 2 BENZHYDRYL 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY]QUINUCLIDINE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; BIOGENIC AMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; L 161664; L 709210; L 732106; N (3 DIETHYLAMINOPROPYL) 4 (N,N DIPENTYLCARBAMOYL) 1 (N,N DIPHENYLCARBAMOYL) 2 PIPERAZINECARBOXAMIDE; N ACETYLTRYPTOPHAN 3,5 BIS(TRIFLUOROMETHYL)BENZYL ESTER; RECEPTOR SUBTYPE; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

BINDING AFFINITY; BINDING SITE; CONFORMATION; HUMAN; NONHUMAN; RECEPTOR BINDING; REVIEW;

AMINO ACID SEQUENCE; BINDING, COMPETITIVE; CLONING, MOLECULAR; GTP-BINDING PROTEINS; HUMAN; LIGANDS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RECEPTORS, ADRENERGIC; RECEPTORS, CELL SURFACE; RECEPTORS, PEPTIDE; RECEPTORS, TACHYKININ; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029093852     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/1056-8719(95)00002-Y     Document Type: Review

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