Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

Science

Volumn 269, Issue 5224, 1995, Pages 690-693

  Stoyanov, Borislav ^a   Volinia, Stefano ^b   Hanck, Theodor ^a   Rubio, Ignacio ^a   Loubtchenkov, Michael ^a   Malek, Daria ^c   Stoyanova, Stefka ^a   Vanhaesebroeck, Bart ^b   Dhand, Ritu ^b   Nürnberg, Bernd ^d   Gierschik, Peter ^c   Seedorf, Klaus ^e   Hsuan, J Justin ^b   Waterfield, Michael D ^b,f   Wetzker, Reinhard ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF ULM   (Germany)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN TARGETING; SECOND MESSENGER; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; YEAST;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; CLONING, MOLECULAR; ENZYME ACTIVATION; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMAN; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOLS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

MAMMALIA;

EID: 0029090212     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.7624799     Document Type: Article

References (32)