Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes

Journal of Clinical Investigation

Volumn 96, Issue 1, 1995, Pages 438-446

  Yamazaki, Tsutomu ^a   Komuro, Issei ^a   Kudoh, Sumiyo ^a   Zou, Yunzeng ^a   Shiojima, Ichiro ^a   Mizuno, Takehiko ^a   Takano, Hiroyuki ^a   Hiroi, Yukio ^a   Ueki, Kohjiro ^a   Tobe, Kazuyuki ^a   Kadowaki, Takashi ^a   Nagai, Ryozo ^a   Yazaki, Yoshio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

cardiac hypertrophy; mitogen activated protein kinase; mitogen activated protein kinase kinase; Raf 1 kinase; signal transduction

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE C;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MECHANICAL STRESS; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0029090205     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118054     Document Type: Article

References (48)

1. Levy, D., R. J. Garrison, D. D. Savage, W. B. Kannel, and W. P. Castelli. 1990. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study. N. Engl. J. Med. 322:1561-1566.
2. Komuro, I., and Y. Yazaki. 1993. Control of cardiac gene expression by mechanical stress. Annu. Rev. Physiol. 55:55-75.
3. Komuro, I., M. Kurabayashi, F. Takaku, and Y. Yazaki. 1988. Expression of cellular oncogenes in the myocardium during the developmental stage and pressure overload hypertrophy of the rat heart. Circ. Res. 62:1075-1079.
4. Mulvagh, S. L., L. H. Michael, M. B. Perryman, R. Roberts, and M. D. Schneider. 1987. A hemodynamic load in vivo induces cardiac expression of the cellular oncogene, c-myc. Biochem. Biophys. Res. Commun. 147:627-36.
5. Komuro, I., T. Kaida, Y. Shibazaki, M. Kurabayashi, F. Takaku, and Y. Yazaki. 1990. Stretching cardiac myocytes stimulates proto-oncogene expression. J. Biol. Chem. 265:3595-3598.
6. Komuro, I., Y. Katoh, T. Kaida, Y. Shibazaki, M. Kurabayashi, F. Takaku, and Y. Yazaki. 1991. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. J. Biol. Chem. 266:1265-1268.
7. Yamazaki, T., K. Tobe, E. Hoh, K. Maemura, T. Kaida, I. Komuro, H. Tamemoto, T. Kadowaki, R. Nagai, and Y. Yazaki. 1993. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J. Biol. Chem. 268:12069-12076.
8. Gomez, N., and P. Cohen. 1991. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature (Lond.). 353:170-173.
9. Ahn, N. G., R. Seger, R. L. Bratlien, C. D. Diltz, N. K. Tonks, and E. G. Krebs. 1991. Multiple components in an EGF-stimulated protein kinase cascade. In vitro activation of a MBP/MAP2 kinase. J. Biol. Chem. 266:4220-4227.
10. Matsuda, S., H. Kosako, K. Takenaka, K. Moriyama, H. Sakai, T. Akiyama, Y. Gotoh, and E. Nishida. 1992. Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade. EMBO (Eur. Mol. Biol. Org.) J. 11:973-982.
11. Nishida, E., and Y. Gotoh. 1993. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18:128-131.
12. Zheng, C-F., and K.-L. Guan. 1994. Activation of MEK family kinase requires phosphorylation of two conserved Ser/Thr residues. EMBO (Eur. Mol. Biol. Org.) J. 13:1123-1131.
13. Kyriakis, J. M., H. App, X. Zhang, P. Banerjee, D. L. Brautigan, U. R. Rapp, and J. Avruch. 1992. Raf-1 activates MAP kinase-kinase. Nature (Lond.). 358:417-421.
14. Lange-Carter, C. A., A. M. Pleiman, K. J. Blumer, and G. L. Johnson. 1993. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science (Wash. DC). 260:315-319.
15. Wood, K. W., C. Sarnecki, T. M. Roberts, and J. Blenis. 1992. Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1 and RSK. Cell. 68:1041-1050.
16. Davis, R. J. 1993. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:14553-14556.
17. Sturgill, T. W., L. B. Ray, E. Erickson, and J. L. Mailer. 1988. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature (Lond.). 334:715-718.
18. Ward, G. E., and M. W. Kirschner. 1990. Identification of cell cycleregulated phosphorylation sites on nuclear lamin C. Cell. 61:561-577.
19. Baker, K. M., G. W. Booz, and D. E. Dostal. 1992. Cardiac actions of angiotensin II: role of an intracardiac renin-angiotensin system. Annu. Rev. Physiol. 54:227-241.
20. Linz, W., B. A. Schoelkens, and D. Ganten. 1989. Converting enzyme inhibitor specifically prevents development and induces the regression of cardiac hypertrophy in rats. Clin. Exp. Hypertens. 11:1325-1350.
21. Baker, K. M., M. I. Cherin, S. K. Wixon, and J. F. Aceto. 1990. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am. J. Physiol. 259:H324-H332.
22. Schunkert, H., V. J. Dzau, S. S. Tang, A. T. Hirsch, C. S. Apstein, and B. H. Lorell. 1990. Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy: effect on coronary resistance, contractility, and relaxation. J. Clin. Invest. 86:1913-1920.
23. Simpson, P., and S. Savion. 1982. Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Circ. Res. 50:101-116.
24. Crews, C. M., A. Alessandrini, and R. L. Erikson. 1992. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science (Wash. DC). 258:478-480.
25. Izumi, T., H. Tamemoto, M. Nagao, T. Kadowaki, F. Takaku, and M. Kasuga. 1991. Insulin and platelet derived growth factor stimulate phosphorylation of the c-raf product at serine and threonine residues in intact cells. J. Biol. Chem. 266:7933-7939.
26. Ueki, K., S. Matsuda, K. Tobe, Y. Gotoh, H. Tamemoto, M. Yachi, Y. Akanuma, Y. Yazaki, E. Nishida, and T. Kadowaki. 1994. Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 insulin and phorbol ester stimulation. J. Biol. Chem. 269:15756-15761.
27. Kosako, H., E. Nishida, and Y. Gotoh. 1993. cDNA cloning of MAP kinase kinase reveals kinase cascade pathways in yeasts to vertebrates. EMBO (Eur. Mol. Biol. Org.) J. 12:787-794.
28. Tobe, K., T. Kadowakj, H. Tamemoto, K. Ueki, K. Hara, O. Koshio, K. Momomura, Y. Gotoh, E. Nishida, Y. Akanuma. et al. 1991. Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues. J. Biol. Chem. 266:24793-24803.
29. Tobe, K., T. Kadowaki, K. Hara, Y. Gotoh, H. Kosako, S. Matsuda, H. Tamemoto, K. Ueki, Y. Akanuma. E. Nishida, and Y. Yazaki. 1992. Sequential activation of MAP kinase activator, MAP kinases, and S6 peptide kinase in intact rat liver following insulin injection. J. Biol. Chem. 267:21089-21097.
30. Boulton, T. G., S. H. Nye, D. J. Robbins, N. Y. Ip, E. Radziejewska, S. D. Morgenbesser, R. A. DePinho, N. Panayotatos, M. H. Cobb, and G. D. Yanco-poulos. 1991. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell. 65:663-675.
31. Sadoshima, J., Y. Xu, H. S. Slayter, and S. Izumo. 1993. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell. 75:977-984.
32. Kojima, M., I. Shiojima, T. Yamazaki, I. Komuro, Y. Zou, Y. Wang, T. Mizuno, K. Ueki, K. Tobe, T. Kadowaki, et al. 1994. Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. Circulation. 89:2204-2211.
33. Komuro, I., Y. Shibazaki, M. Kurabayashi, F. Takaku, and Y. Yazaki. 1990. Molecular cloning of gene sequences from rat heart rapidly responsive to pressure overload. Circ. Res. 66:979-985.
34. Pelech, S. L., and J. S. Sanghera. 1992. MAP kinases: charting the regulatory pathways. Science (Wash. DC). 257:1355-1356.
35. Leberer, E., D. Dignard, D. Harcus, D. Y. Thomas, and M. Whiteway. 1992. The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components. EMBO (Eur. Mol. Biol. Org.) J. 11:4815-4824.
36. Sadoshima, J., and S. Izumo. 1993. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO (Eur. Mol. Biol. Org.) J. 12:1681-1692.
37. Kolch, W., G. Heidecker, G. Kochs, R. Hummel, H. Vahidi, H. Mischak, G. Finkenzeller, D. Marme, and U. R. Rapp. 1993. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature (Lond.). 364:249-252.
38. Lissoos, T. W., D. W. A. Beno, and B. H. Davis. 1993. 1, 25-dihydroxyvitamin D3 activates Raf kinase and Raf perinuclear translocation via a protein kinase C-dependent pathway. J. Biol. Chem. 268:25132-25138.
39. ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature (Lond.). 364:308-313.
40. Thorbum, J., J. A. Frost, and A. Thorburn. 1994. Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J. Cell Biol. 126:1565-1572.
41. Thorburn, A., J. Thorburn, S.-Y. Chen, S. Powers, H. E. Shubeita, J. R. Feramisco, and K. R. Chien. 1993. HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. J. Biol. Chem. 268:2244-2249.
42. Baker, K. M., and J. F. Aceto. 1987. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am. J. Physiol. 259:H610-618.
43. Katoh, Y., I. Komuro, Y. Shibazaki, H. Yamaguchi, and Y. Yazaki. 1989. Angiotensin II induces hypertrophy and oncogene expression in cultured cardiac myocytes. Circulation. 80(Suppl. II):II-450.
44. Dostal, D. E., and K. M. Baker. 1992 Angiotensin II stimulation of left ventricular hypertrophy in adult rat heart. Am. J. Hypertens. 5:276-280.
45. Brewster, J. L., T. de Valoir, N. D. Dwyer, E. Winter, and M. C. Gustin, 1993. An osmosensing signal transduction pathway in yeast. Science ( Wash. DC). 259:1760-1763.
46. Man, J., J.-D. Lee, L. Ribbs, and R. J Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science (Wash. DC). 265:808-811.
47. Galcheva-Gargova, Z., B. Derijard, I.-H. Wu, and R. J. Davis. 1994. An osmosensing signal transduction pathway in mammalian cells. Science (Wash. DC). 265:806-808.
48. Komuro, I., and Y. Yazaki. 1994. Intracellular signaling pathways in cardiac myocytes induced by mechanical stress. Trends Cardiovasc. Med. 4:117-121.