Synthesis and characterization of thiobutyltriphenylphosphonium bromide, a novel thiol reagent targeted to the mitochondrial matrix

Archives of Biochemistry and Biophysics

Volumn 322, Issue 1, 1995, Pages 60-68

  Burns, Rhys J ^a   Smith, Robin A J ^a   Murphy, Michael P ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Glutathione; Mitochondria; Oxidative stress; Protein mixed disulfides; Thiobutyltriphenylphosphonium bromide; Thiols

Indexed keywords

EID: 0029090125     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1995.1436     Document Type: Article

References (26)

1. Chance, B., Sies, H., and Boveris, A. (1979) Physiol. Rev. 59, 527-604.
2. Shigenaga, M. K., Hagen, T. M., and Ames, B. N. (1994) Proc. Natl. Acad. Sci. USA 91, 10771-10778.
3. Richter, C., Park, J.-W., and Ames, B. (1988) Proc. Natl. Acad. Sci. USA 85, 6465-6467.
4. Tyler, D. (1992) The Mitochondrion in Health and Disease, VCH, New York.
5. Darley-Usmar, V., and Schapira, A. H. V. (Eds.) (1994) Mitochondria: DNA, Proteins and Disease, Portland Press, London.
6. Griffith, O. W., and Meister, A. (1985) Proc. Natl. Acad. Sci. USA 82, 4668-4672.
7. Jocelyn, P. C. (1975) Biochim. Biophys. Acta 396, 427-436.
8. Meredith, M. J., and Reed, D. J. (1982) J. Biol. Chem. 257, 3747-3753.
9. Reed, D. J. (1990) Annu. Rev. Pharmacol. Toxicol. 30, 603-631.
10. Riley, M. V., and Lehninger, A. L. (1964) J. Biol. Chem. 239, 2083-2089.
11. Ravindranath, V., and Reed, D. J. (1990) Biochem. Biophys. Res. Commun. 169, 1075-1079.
12. Scholz, R. W., Saini, A. K., Reddy, P. C., and Reddy, C. C. (1994) Biochem. Mol. Biol. Int. 34, 1215-1225.
13. Uhlig, S., and Wendel, A. (1992) Life Sci. 51, 1083-1094.
14. Jenner, P. (1993) Acta Neurol. Scand. 87 (Suppl. 146), 6-13.
15. Fagian, M. M., Pereira-da-Silva, L., Martins, I. S., and Vercesi, A. E. (1990) J. Biol. Chem. 265, 19955-19960.
16. Petronilli, V., Costantini, P., Scorrano, L., Colonna, R., Passa-monti, S., and Bernardi, P. (1994) J. Biol. Chem. 269, 16638-16642.
17. Liberman, E. A., Topaly, V. P., Tsofina, L. M., Jasaitis, A. A., and Skulachev, V. P. (1969) Nature 222, 1076-1078.
18. Hoek, J. B., Nicholls, D. G., and Williamson, J. R. (1980) J. Biol. Chem. 255, 1458-1464.
19. Ellman, G. L. (1959) Arch. Biochem. Biophys. 82, IQ-11.
20. Chappell, J. B., and Hansford, R. G. (1972) in Subcellular Components: Preparation and Fractionation (Birnie, G. D., Ed.), pp. 77-91, Butterworths, London.
21. Gomall, A. G., Bardawill, C. J., and David, M. M. (1949) J. Biol. Chem. 177, 751-766.
22. Reynafaije, B., Costa, L. E., and Lehninger, A. L. (1985) Anal. Biochem. 145, 406-418.
23. Brown, G. C., and Brand, M. D. (1985) Biochem. J. 225, 399-405.
24. Hafner, R. P., Nobes, C. D., McGown, A. D., and Brand, M. D. (1988) Eur. J. Biochem. 178, 511-518.
25. Gilbert, H. F. (1990) Adu. Enzymol. 63, 69-172.
26. Kosower, N. S., Kosower, E. M., and Wertheim, B. (1969) Biochem. Biophys. Res. Commun. 37, 593-596.