Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

Genes and Development

Volumn 9, Issue 13, 1995, Pages 1608-1621

  Cole, Timothy J ^a   Blendy, Julie A ^a   Monaghan, A Paula ^a   Krieglstein, Kerstin ^b   Schmid, Wolfgang ^a   Aguzzi, Adriano ^c   Fantuzzi, Giamila ^d   Hummler, Edith ^e   Unsicker, Klaus ^a   Schütz, Günther ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^e NONE

Author keywords

chromaffin cells; gene targeting; Glucocorticoids; lung development; steroid hormone receptor

Indexed keywords

ADRENALIN; ALDOSTERONE; CORTICOSTERONE; CORTICOTROPIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; LIVER ENZYME; STEROID 11BETA MONOOXYGENASE; SYNTHETASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATELECTASIS; CHROMAFFIN CELL; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; EMBRYO; FEEDBACK SYSTEM; FETUS LUNG MATURATION; GENE TARGETING; HORMONE DEFICIENCY; HYPERADRENOCORTICISM; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0029088326     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.13.1608     Document Type: Article

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