Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence β-casein gene expression

Molecular Endocrinology

Volumn 9, Issue 9, 1995, Pages 1223-1232

  Raught, Brian ^a   Liao, Warren S L ^b   Rosen, Jeffrey M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CASEIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; BREAST DEVELOPMENT; ENHANCER REGION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; LACTATION; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION;

ANIMAL; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CASEINS; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CONSENSUS SEQUENCE; DNA; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; HYDROCORTISONE; MAMMAE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEINS; RATS; RECOMBINANT PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029086784     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/mend.9.9.7491114     Document Type: Article

References (42)

1. Raught B, Khursheed B, Kazansky A, Rosen J 1994 YY 1 represses β-casein gene expression by preventing the formation of a lactation-associated complex. Mol Cell Biol 14: 1752-1763
2. Schmltt-Ney M, Doppler W, Ball RK, Groner B 1991 Beta-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor. Mol Cell Biol 11: 3745-3755
3. Doppler W, Groner B, Ball RK 1989 Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat beta-casein gene promoter constructs in a mammary epithelial cell line. Proc Natl Acad Sci USA 86: 104-108
4. Ball RK, Friis RR, Schoenenberger CA, Doppler W, Groner B 1988 Prolactin regulation of beta-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line. EMBO J 7: 2089-2095
5. Streuli CH, Bailey N, Bissell MJ 1991 Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expresion in the absence of cell-cell interaction and morphological polarity. J Cell Biol 115: 1383-1395
6. Roskelley CD, Desprez PY, Bissell MJ 1994 Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc Natl Acad Sci USA 91: 12378-12382
7. Lee KF, DeMayo FJ, Atiee SH, Rosen JM 1988 Tissue-specific expression of the rat beta-casein gene in transgenic mice. Nucleic Acids Res 16: 1027-1041
8. Threadgill DW, Womack JE 1990 Genomic analysis of the major bovine milk protein genes. Nucleic Acids Res 18: 6935-6942
9. Deleted in proof.
10. Lee KF, Atiee SH, Henning SJ, Rosen JM 1989 Relative contribution of promoter and intragenic sequences in the hormonal regulation of rat beta-casein transgenes. Mol Endocrinol 3: 447-453
11. Eisenstein RS, Rosen JM 1988 Both cell substratum regulation and hormonal regulation of milk protein gene expression are exerted primarily at the posttranscrip-tional level. Mol Cell Biol 8: 3183-3190
12. Altiok S, Groner B 1994 Beta-casein mRNA sequesters a single-stranded nucleic acid-binding protein which negatively regulates the beta-casein gene promoter. Mol Cell Biol 14: 6004-6012
13. Poyet P, Henning SJ, Rosen JM 1989 Hormone-dependent beta-casein mRNA stabilization requires ongoing protein synthesis. Mol Endocrinol 3: 1961-1968
14. Puissant C, Houdebine L-M 1991 Cortisol induces rapid accumulation of whey acid protein mRNA but not of as 1 and β-casein mRNA in rabbit mammary explants. Cell Biol Int Rep 15: 121-129
15. Doppler W, Hock W, Hofer P, Groner B, Ball RK 1990 Prolactin and glucocorticoid hormones control transcription of the beta-casein gene by kinetically distinct mechanisms. Mol Endocrinol 4: 912-919
16. Johnson PF, Landschulz WH, Graves BJ, McKnight SL 1987 Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev 1: 133-146
17. Ben-Or S, Okret S 1993 Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development. Mol Cell Biol 13: 331-340
18. MacDougald OA, Cornelius P, Lin F-T, Chen SS, Lane MD 1994 Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein a and 8 genes in 3T 3-L 1 adipocytes and white adipose tissue. J Biol Chem 269: 19401-19407
19. Williams P, Ratajczak T, Lee SC, Ringold GM 1991 AGP/EBP(LAP) expressed in rat hepatoma cells interacts with multiple promoter sites and is necessary for maximal glucocorticoid induction of the rat α-1 acid glycoprotein gene. Mol Cell Biol 11: 4959-4965
20. Chen H-M, Liao WS-L 1993 Molecular analysis of the differential hepatic expression of rat kininogen family genes. Mol Cell Biol 13: 6766-6777
21. Huang JH, Liao WS-L 1994 Induction of the mouse serum amyloid A 3 gene by cytokines requires both C/EBP family proteins and a novel constitutive factor. Mol Cell Biol 14: 4475-4484
22. Descombes P, Schibler U 1991 A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67: 569-579
23. Ray A, Ray BK 1994 Serum amyloid A gene expression under acute-phase conditions involves participation of inducible C/EBP-J 3 and C/EBP-S and their activation by phosphorylation. Mol Cell Biol 14: 4324-4332
24. Alam T, An MR, Papaconstantinou J 1992 Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response. J Biol Chem 267: 5021-5024
25. Laird JE, Jack L, Hall L, Boulton AP, Parker D, Craig RK 1988 Structure and expression of the guinea-pig α-lactalbumin gene. Biochem J 254: 85-94
26. Cao Z, Umek RM, McKnight SL 1991 Regulated expression of three C/EBP isoforms during adipose conversion of 3T 3-L 1 cells. Genes Dev 5: 1538-1552
27. Poli V, Mancini FP, Cortese R 1990 IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell 63: 643-653
28. Isshiki H, Akira S, Sugita T, Nishio Y, Hashimoto S, Pawlowski T, Suematsu S, Kishimoto T 1991 Reciprocal expression of NF-IL 6 and C/EBP in hepatocytes: Possible involvement of NF-IL 6 in acute phase protein gene expression. New Biol 3: 63-70
29. Lamb P, McKnight SL 1991 Diversity and specificity in transcriptional regulation: The benefits of heterotypic dimerization. Trends Biochem Sci 16: 417-422
30. Nishio Y, Isshiki H, Kishimoto T, Akira S 1993 A nuclear factor for interleukin-6 expression (NF-IL 6) and the glucocorticoid receptor synergistically activate transcription of the rat a 1-acid glycoprotein gene via direct proteinprotein interaction. Mol Cell Biol 13: 1854-1862
31. Wegner M, Cao Z, Rosenfeld MG 1992 Calcium-regulated phosphorylation within the leucine zipper of C/EBPβ. Science 256: 370-373
32. Nakajima T, Kinoshita S, Sasagawa T, Sasaki K, Naruto M, Kishimoto T, Akira S 1993 Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL 6. Proc Natl Acad Sci USA 90: 2207-2211
33. Metz R, Ziff E 1991 cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to translocate to the nucleus and induce c-fos transcription. Genes Dev 5: 1754-1766
34. Hsu W, Chen-Kiang S 1993 Convergent regulation of NF-IL 6 and Oct-1 synthesis by interleukin-6 and retinoic acid signaling in embryonal carcinoma cells. Mol Cell Biol 13: 2515-2523
35. Rosen JM, O’Neal DL, McHugh JE, Comstock JP 1978 Progesterone-mediated inhibition of casein mRNA and polysomal casein synthesis in the rat mammary gland during pregnancy. Biochemistry 17: 290-297
36. Tahara SM, Dietlin TA, Dever TE, Merrick WC, Worrilow LM 1991 Effect of eukaryotic initiation factor 4F on AUG selection in a bicistronic mRNA. J Biol Chem 266: 3594-3601
37. Chammas R, Taverna D, Celia N, Santos C, Hynes NE 1994 Laminin and tenascin assembly and expression regulate HC 11 mouse mammary cell differentiation. J Cell Sci 107: 1031-1040
38. Schmidhauser C, Casperson GF, Myers CA, Sanzo KT, Bolten S, Bissell MJ 1992 A novel transcriptional enhancer is involved in the prolactin-and extracellular matrix-dependent regulation of beta-casein gene expression. Mol Biol Cell 3: 699-709
39. Rana B, Mischoulon D, Xie Y, Bucher NLR, Farmer SR 1994 Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: Reciprocal expression of C/EBPa and immediate-early growth response transcription factors. Mol Cell Biol 14: 5858-5869
40. Pierre S, Jolivet G, Devinoy E, Houdebine L-M 1994 A combination of distal and proximal regions is required for efficient prolactin regulation of transfected rabbit as 1-casein chloramphenical acetyltransferase constructs. Mol Endocrinol 8: 1720-1730
41. Miner JN, Yamamoto KR 1991 Regulatory crosstalk at composite response elements. Trends Biochem Sci 16: 423-426
42. Li S, Rosen JM 1995 Nuclear factor 1 and mammary gland factor (STAT 5) play a critical role in regulating whey acidic protein expression in transgenic mice. Mol Cell Biol 15: 2063-2070