Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases

FASEB Journal

Volumn 9, Issue 11, 1995, Pages 1051-1058

  Goetzl, Edward J ^a,c   An, Songzhu ^a   Smith, William L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Box 0711 ^*  (United States)

Author keywords

arachidonic acid; cyclooxygenase; immunity; leukotriene; lipoxygenase; prostaglandin; receptor

Indexed keywords

LEUKOTRIENE; LIPOXYGENASE; MEMBRANE RECEPTOR; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE;

ARACHIDONIC ACID METABOLISM; CELL DIFFERENTIATION; CELL MIGRATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; ICOSANOID METABOLISM; IMMUNITY; PHYSIOLOGY; PRIORITY JOURNAL; REVIEW; TISSUE SPECIFICITY;

EID: 0029086681     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.9.11.7649404     Document Type: Review

References (56)

1. Samuelsson, B., Goldyne, M., Granstrom, E., Hamberg, M., Hammarstrom, S., and Malmsten, C. (1978) Prostaglandins and thromboxanes. Annu. Rev. Biochem. 47, 997-1029
2. Samuelsson, B. (1983) Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220, 568-575
3. Needleman, P., Turk, J., Jakschik, B. A., Morrison, A. R., and Lefkowith, J. B. (1986) Arachidonic acid metabolism. Annu. Rev. Biochem. 55, 69-102
4. Cellular Generation, Transport and Effects of Eicosanoids: Biological Roles and Pharmacological Intervention (1994) (Goetzl, E. J., Lewis, R. A., and Rola-Pleszczynski, M., eds) N.Y. Academy of Sciences, New York
5. Fletcher, B. S., Kujubu, D. A., Perrin, D. M., and Herschman, H. R. (1992) Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J. Biol. Chem. 267, 4338-4344
6. O'Banion, M. K., Winn, V. D., and Young, D. A. (1992) cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89, 4088-4892
7. Ford-Hutchinson, A. W., Gresser, M., and Young, R. N. (1994) 5-Lipoxygenase. Annu. Rev. Biochem. 63, 383-417
8. Kennedy, B. P., Diehl, R. E., Boie, Y., Adam, M., and Dixon, R. A. F. (1991) Gene characterization and promoter analysis of the human 5-lipoxygenase-activating protein (FLAP). J. Biol. Chem. 266, 8511-8516
9. Lam, B. K., Penrose, J. F., Freeman, G. J., and Austen, K. F. (1994) Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4. Proc. Natl. Acad. Sci. USA 91, 7663-7667
10. Welsch, D. J., Creeley, D. P., Hauser, S. D., Mathis, K. J., Krivi, G. G., and Isakson, P. C. (1994) Molecular cloning and expression of human leukotriene-C4 synthase. Proc. Natl. Acad. Sci. USA 91, 9745-9749
11. Waite, M. (1987) The Phospholipases, Plenum, New York
12. Coleman, R. A., Smith, W. L., and Narumiya, S. (1994) VIII. International Union of Pharmacology Classification of Prostanoid Receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev. 46, 205-229
13. Koo, C. H., Sherman, J. W., Baud, L., and Goetzl, E. J. (1989) Molecular diversity of human leukocyte receptors for leukotrienes. In Advances in Prostaglandin, Thromboxane and Leukotriene Research (Samuelsson, B., Wong, P.Y.-K., and Sun, F. F., eds) vol. 19, pp. 191-194, Raven Press, New York
14. Schafer, A. I. (1982) Deficiency of platelet lipoxygenase activity in myeloproliferative disorders. N. Engl. J. Med. 306, 381-386
15. Marijevic-Aleksic, N., Ghaddar, H., McPhedran, P., and Wu, K. K. (1994) Bleeding disorder due to platelet cyclooxygenase-1 (COX-1) deficiency. Blood 84(suppl.), 320a
16. 60 to Leu mutation of the human thromboxane Ai2 receptor in a dominantly inherited bleeding disorder. J. Clin. Invest. 94, 1662-1667
17. Chen, X.-S., Sheller, J. R., Johnson, E. N., and Funk, C. D. (1994) Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 372, 179-182
18. Roberts, L. J., II, Sweetman, B. J., Lewis, R. A., Austen, K. F., and Oates, J. A. (1980) Increased production of prostaglandin D2 in patients with systemic mastocytosis. N. Engl. J. Med. 303, 1400-1404
19. Awad, J. A., Morrow, J. D., Roberts, L. J., II (1994) Detection of the major urinary metabolite of prostaglandin D2 in the circulation and urine: demonstration of elevated levels in patients with disorders of systemic mast cell activation. J. Allergy Clin. Immunol. 93, 817-824
20. Greally, P., Cook, A. J., Sampson, A. P., Coleman, R., Chambers, S., Piper, P. J., and Price, J. F. (1994) Atopic children with cystic fibrosis have increased urinary leukotriene E4 concentrations and more severe pulmonary disease. J. Allergy Clin. Immunol. 93, 100-107
21. Kikawa, Y., Miyanomae, T., Inoue, Y., Saito, M., Nakai, A., Shigematsu, Y., Hosoi, S., and Sudo, M. (1992) Urinary leukotriene E4 after exercise challenge in children with asthma. J. Allergy Clin. Immunol. 89, 1111-1119
22. Kuhn, H., Belkner, J., Zaiss, S., Fahrenklemper, T., and Wohlfeil, S. (1994) Involvement of 15-lipoxygenase in early stages of atherogenesis. J. Exp. Med. 179, 1903-1911
23. Klickstein, L. B., Shapleigh, C., and Goetzl, E. J. (1980) Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factore in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis. J. Clin. Invest. 66, 1166-1170
24. Wittenberg, R. H., Willburger, R. E., Kleemeyer, K. S., and Peskar, B. A. (1993) In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases. Arthritis Rheum. 36, 1444-1450
25. Mayatepek, E., Lehmann, W.-D., Fauler, J., Tsikas, D., Frolich, J. C., Schutgens, R. B. H., Wanders, R. J. A., and Keppler, D. (1993) Impaired degradation of leukotrienes in patients with peroxisome deficiency disorders. J. Clin. Invest. 91, 881-888
26. Bresnahan, B. A., Wu, S., Fenoy, F. J., Roman, R. J., and Lianos, E. A. (1992) Mesangial cell immune injury: hemodynamic role of leukocyte-and platelet-derived eicosanoids. J. Clin. Invest. 90, 2304-2312
27. Smith, W. L. (1992) Prostanoid biosynthesis and mechanisms of action. Am. J. Physiol. 263, F181-F191
28. Riendeau, D., Guay, J., Weech, P. K., Laliberte, F., Yergy, J., Li, C., Desmarais, S., Perrier, H., Liu, S., Nicoll-Griffith, D., and Street, I. P. (1994) Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85 kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosa-tetraenoic acid by calcium ionophore-challenged platelets. J. Biol. Chem. 269, 15619-15624
29. Picot, D., Loll, P. J., and Garavito, M. (1994) The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 367, 243-249
30. Kujubu, D. A., and Herschman, H. R. (1992) Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene. J. Biol. Chem. 267, 7991-7994
31. Murakami, M., Matsumoto, R., Austen, K. F., and Arm, J. P. (1994) Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. J. Biol. Chem. 269, 22269-22275
32. Meade, E. A., Smith, W. L., and DeWitt, D. L. (1993) Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 268, 6610-6614
33. O'Sullivan, G. M., Chilton, F. H., Huggins, E. M. Jr., and McCall, C. E. (1992) Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase. J. Biol. Chem. 267, 14547-14550
34. Masferrer, J. L., Zweifel, B. S., Manning, P., Hauser, S., Leahy, K., Smith, W., Isakson, P., and Seibert, K. (1994) Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc. Natl. Acad. Sci. USA 91, 3228-3232
35. Chilton, F. (1989) Potential phospholipid source(s) of arachidonate used for the synthesis of leukotrienes by the human neutrophil. Biochem. J. 258, 327-333
36. Zhang, Y.-Y., Lind, B., Rad mark, O., and Samuelsson, B. (1993) Iron content of human 5-lipoxygenase, effects of mutation regarding conserved histidine residues. J. Biol. Chem. 268, 2535-2541
37. Boyington, J.C., Gaffney, G.J., and Amzel, L.M. (1993) The three-dimensional structure of an arachidonic acid 15-lipoxygenase. Science 260, 1482-1486
38. Woods, J., Evans, J. F., Ethier, D., Scott, S., Vickers, P. J., Hearn, L., Heibein, J. A., Charleson, S., and Singer, I. I. (1993) 5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J. Exp. Med. 178, 1935-1936
39. Lepley, R. A., and Fitzpatrick, F. A. (1994) 5-lipoxygenase contains a functional src homology 3-binding motif that interacts with the src homology 3 domain of Grb2 and cytoskeletal proteins. J. Biol. Chem. 269, 24163-24168
40. Oming, L., Gierse, J. K., and Fitzpatrick, F. A. (1994) The bifunctional enzyme leukotriene A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity. J. Biol. Chem. 269, 11269-11273
41. Fiore, S., Maddox, J. F., Ferez, H. D., and Serhan, C. N. (1994) Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor. J. Exp. Med. 180, 253-260
42. Zeng, L., An, S., and Goetzl, E. J. (1994) Coordinate regulation of expression of prostaglandin E2 receptors of the EP2-and EP3-subtypes on U937 human monocytic cells. Mol. Biol. Cell 5, 68a
43. Namba, T., Sugimoto, Y., Negishi, M., Irle, A., Ushkubi, F., Kakizuka, A., Ito, S., Ichikawa, A., and Narumiya, S. (1993) Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature 365, 166-170
44. An, S., Yang, J., So, S. W., Zeng, L., and Goetzl, E. J. (1994) Isoforms of the EP3 subtype of human prostaglandin E2 receptor transduce both intracellular calcium and cAMP signals. Biochemistry 33, 14496-14502
45. Nusing, R., Lesch, R., and Ullrich, V. (1990) Immunohistochemical localization of thromboxane synthase in human tissues. Eicosanoids 3, 53-61
46. Tippetts, M. T., Varnum, B. C., Lim, R. W., and Herschman, H. R. (1988) Tumor promoter-inducible genes are differentially expressed in the developing mouse. Mol. Cell. Biol. 8, 4570-4574
47. + T lymphoblasts. J Immunol. 154, 1041-1047
48. Ushikubi, F., Aiba, Y., Nakamura, K., Namba, T., Hirata, M., Mazda, O., Katsura, Y., and Narumiya, S. (1993) Thromboxane Ai2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis. J. Exp. Med. 178, 1825-1830
49. Brown, D. M., Warner, G. L., Ales-Martinez, J. E., Scott, D. W., and Phipps, R. P. (1992) Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes. Clin. Immunol. Immunopathol. 63, 221-229
50. Roper, R. L. and Phipps, R. P. (1992) Prostaglandin E2 and cAMP inhibit B lymphocyte activation and simultaneously promote IgE and IgG1 synthesis. J. Immunol 149, 2984-2991
51. Yamaoka, K. A., Claesson, H.-E., and Rosen, A. (1989) Leukotriene B4 enhances activation, proliferation, and differentiation of human B lymphocytes. J. Immunol. 143, 1996-2000
52. Leppert, D., Hauser, S. L., Kishiyama, J. L., An, S., Zeng, L., and Goetzl, E. J. (1995) Prostaglandin E2 and leukotriene B4 stimulation of matrix metalloproteinase-dependent migration of human T cells across a model basement membrane. FASEB J. 9, A853
53. Goodwin, J. S., Bankhurst, A. D., and Messner, R. P. (1977) Suppression of human T-cell mitogenesis by prostaglandin. J. Exp. Med. 146, 1719-1726
54. Payan, D. G., Missirian-Bastian, A., and Goetzl, E. J. (1984) Human T-lymphocyte subset specificity of the regulatory effects of leukotriene B4. Proc. Natl. Acad. Sci. USA 81, 3501-3505
55. Betz, M., and Fox, B. S. (1991) Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J. Immunol. 146, 108-113
56. Rola-Pleszezynski, M., Bouvrette, L., Gingras, D., and Girard, M. (1987) Identification of interferon-gamma as the lymphokine that mediates leukotriene B4-induced immunoregulation. J. Immunol. 139, 513-517