Serum total homocysteine and coronary heart disease

International Journal of Epidemiology

Volumn 24, Issue 4, 1995, Pages 704-709

  Arnesen, Egil ^a   Refsum, Helga ^b   Bønaa, Kaare H ^a   Ueland, Per Magne ^b   Førde, Olav H ^a   Nordrehaug, Jan E ^b  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Cardiovascular risk factors; Coronary heart disease; Nested case control study; Serum total homocysteine

Indexed keywords

HOMOCYSTEINE;

ADOLESCENT; ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY RISK; FEMALE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; NORMAL HUMAN; NORWAY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CHILD; CORONARY DISEASE; FEMALE; HOMOCYSTEINE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NORWAY; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; RISK FACTORS;

EID: 0029084552     PISSN: 03005771     EISSN: None     Source Type: Journal    
DOI: 10.1093/ije/24.4.704     Document Type: Article

References (32)

1. Mudd S H, Levy H L, Skovby F. Disorders of transsulfuration. In: Scriver C S, Beaudet A L, Sly W L, Valle D (eds). The Metabolic Basis of Inherited Disease. New York: McGraw-Hill Books, 1989, pp. 693-734.
2. McCully K S. Homocysteine theory of arteriosclerosis: development and current status. Atherosclerosis Rev 1983; 11: 157-246.
3. Kang S S, Wong P W K, Malinow M R. Hyperhomocyst-(e)inemia as a risk factor for occlusive vascular disease. Annu Rev Nutr 1992; 12: 279-98.
4. Ueland P M, Refsum H, Brattström L. Plasma homocysteine and cardiovascular disease. In: Francis Jr R B (ed.). Atherosclerotic Cardiovascular Disease. Hemostasis. and Endothelial Function. New York: Marcel Dekker, 1992, pp. 183-236.
5. Holme I, Enger S C, Helgeland A et al. Risk factors and raised atherosclerotic lesions in coronary and cerebral arteries. Arteriosclerosis 1981; 1: 250-56.
6. Malinow M R, Nieto F J, Szklo M, Chambless L E, Bond G. Carotid artery intimal-medial wall thickening and plasma homocysteine in asymptomatic adults. The Atherosclerosis Risk in Communities Study. Circulation 1993; 87: 1107-13.
7. Stampfer M J, Malinow R, Wille B W C et al. A prospective study of plasma homocysteine and risk of myocardial infarction in United States physicians. JAMA 1992; 268: 877-81
8. Bønaa K H, Arnesen E. Association between heart rate and atherogenic blood lipid fractions in a population. The Tromse study. Circulation 1992; 86: 394-405.
9. Thelle D S, Forde O H, Try K, Lehmann R H. The TromsfS heart study: Methods and main results of the cross-sectional study. Acta Med Scand 1976; 200: 107-18.
10. Thelle D S, Arnesen E, Forde OH. The TromsO heart study. Does coffee raise serum cholesterol? N Engl J Med 1983; 308: 1454-57.
11. Bjartveit K, Foss O P, Gjervik T, Lund-Larsen P G. The cardiovascular disease study in Norwegian counties: Background and organization. Acta Med Scand 1979; 634 (Suppl.): 1-70.
12. Central Bureau of Statistics. Causes of Death 1990. Oslo, NOS C 15, 1992.
13. Fiskerstrand T, Refsum H, Kvalheim G, Ueland P M. Homocysteine and other thiols in plasma and urine: Automated determination and sample stability. Clin Chem 1993; 39: 263-71.
14. Refsum H, Ueland P M, Svardal AM. Fully automated fluorescence assay for determining total homocysteine in plasma. Clin Chem 1989; 35: 1921-27.
15. SAS Institute Inc. SASJSTAT User’s Guide, Version 6, Fourth Edition. Cary NC: SAS Institute Ine, 1989.
16. SAS Institute Inc. SAS/STAT Software: The PHREG Procedure, Version 6. SAS Technical Report P-217. Cary NC: SAS Institute Ine, 1991.
17. Andersson A, Isaksson A, Hultberg B. Homocysteine export from erythrocytes and its implication for plasma sampling. Clin Chem 1992; 38: 1311-15.
18. Ubbink J B, Venmaak W J H, Vandermerwe A, Becker P J. The effect of blood sample aging and food consumption on plasma total homocysteine levels. Clin Chim Acta 1992; 207: 119-28.
19. Steering Committee of the Physicians’ Health Study Research Group. Final report on the aspirin component of the ongoing Physicians’ Health Study. N Engl J Med 1991; 325: 373-81.
20. Bender M M, Levy A S, Schucker R E, Yetley E A. Trends in prevalence and magnitude of vitamin and mineral supplement usage and correlation with health status. J Am Diet Assoc 1992; 92: 1096-101.
21. McCully K S, Ragsdale B D. Production of arteriosclerosis by homocysteinemia. Am J Pathol 1970; 61: 1-8.
22. Harker L A, Slichter S J, Scott C R, Ross R. Homocystinemia. Vascular injury and arterial thrombosis. N Engl J Med 1974; 291: 537–43.
23. Harker L A, Ross R, Slichter S J, Scou C R. Homocysteine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis. J Clin Invest 1976; 58: 531–41.
24. Harpel P C, Chang V T, Borth W. Homocysteine and other sulf-hydryl compounds enhance die binding of lipoprotein(a) to fibrin: A potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism. Proc Natl Acad Sci USA 1992; 89: 10 193-97.
25. Lentz S R, Sadler J E. Inhibition of thrombomodulin surface expression and protein-C activation by the thrombogenic agent homocysteine. J Clin Invest 1991; 88: 1906-14.
26. Heinecke J W, Rosen H, Suzuki L A, Chait A. The role of sulfur-containing amino acids in Superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. J Biol Chem 1987; 262: 10 098-103.
27. Parthasarathy S. Oxidation of low density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. Biochim Biophys Acta 1987; 917: 337-40.
28. Blom H J, Engelen D P E, Boers G H J et al. Lipid peroxidation in homocysteinaemia. J Inherit Metab Dis 1992; 15: 419-22.
29. Dudman N P B, Wilcken DEL, Stocker R. Circulating lipid hydroperoxide levels in human hyperhomocysteinemia. Relevance to development of arteriosclerosis. Arterioscler Thromb 1993; 13: 512-16.
30. Brattström L E, Hultberg B L, Hardebo J E. Folic acid responsive postmenopausal homocysteinemia. Metabolism 1985; 34: 1073-77.
31. Wilken DEL, Dudman N P B, Tyrrell P A, Robertson M R. Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: Possible implications for prevention of vascular disease. Metabolism 1988; 37: 697-701.
32. Brattström L E, Israelsson B, Jeppsson J-O, Hultberg B L. Folic acid–an innocuous means to reduce plasma homocysteine. Scand J Clin Lab Invest 1988; 48: 215-21.