Comparison of the kinetic disposition and metabolism of E3810, a new proton pump inhibitor, and omeprazole in relation to S-mephenytoin 4′-hydroxylation status

Clinical Pharmacology and Therapeutics

Volumn 58, Issue 2, 1995, Pages 143-154

  Yasuda, Sanae ^a,b   Horai, Yukio ^a,b   Tomono, Yoshiro ^a,b   Nakai, Hiromu ^a,b   Yamato, Chiyuki ^a,b   Manabe, Kyoko ^a,b   Kobayashi, Kaoru ^a,b   Chiba, Kan ^a,b   Ishizaki, Takashi ^a,b  

^a EISAI CO LTD   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MEPHENYTOIN; OMEPRAZOLE; PROTON PUMP INHIBITOR; RABEPRAZOLE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; HYDROXYLATION; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PHENOTYPE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VOLUNTEER;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; BENZIMIDAZOLES; CROSS-OVER STUDIES; HUMANS; HYDROXYLATION; JAPAN; MALE; MEPHENYTOIN; OMEPRAZOLE; PHENOTYPE; PROTON PUMPS; REFERENCE VALUES; SMOKING;

EID: 0029083823     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1016/0009-9236(95)90192-2     Document Type: Article

References (39)