Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: Ligand binding and intracellular signaling properties

Endocrinology

Volumn 136, Issue 10, 1995, Pages 4629-4639

  Wheeler, Michael B ^a   Gelling, Richard W ^a,b   Mc intosh, Christopher H S ^a,b   Georgiou, John ^a   Brown, John C ^a,b   Pederson, R A ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE; INSULIN;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHO CELL; HORMONAL REGULATION; INSULIN LIKE ACTIVITY; INSULIN RELEASE; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ANIMAL; BASE SEQUENCE; CALCIUM; CELL LINE; CYCLIC AMP; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; GASTRIC INHIBITORY POLYPEPTIDE; ISLETS OF LANGERHANS; MOLECULAR SEQUENCE DATA; RATS; RECEPTORS, GASTROINTESTINAL HORMONE; SUPPORT, NON-U.S. GOV'T;

EID: 0029082308     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo.136.10.7664683     Document Type: Article

References (50)

1. Brown JC, Buchan AMJ, McIntosh CHS, Pederson RA 1989 Gastric inhibitory polypeptide. In: Schultz SG, Makhlouf GM, Rauner BB (eds) Handbook of Physiology, Sect 6. American Physiology Society, Bethesda, pp 403-430
2. Pederson RA 1993 GIP. In: Walsh J, Dockray G (eds) Gut Peptides. Raven Press, New York, pp 217-259
3. Dupre J, Ross SA, Watson D, Brown JC 1973 Stimulation of insulin secretion by gastric inhibitory polypeptide in man. J Clin Endocrinol Metab 37:826-828
4. Nauck M, Schmidt WE, Ebert R, Strietzel J, Cantor P, Hoffmann G, Creutzfeldt W 1989 Insulinotropic properties of synthetic human gastric inhibitory polypeptide in man: interactions with glucose, phenylalanine, and cholecystokinin-8. J Clin Endocrinol Metab 69: 654-662
5. Pederson RA, Brown JC 1976 The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas. Endocrinology 99:780 -785
6. Holst JJ 1994 Glucagonlike peptide 1: a newly discovered gastrointestinal hormone. Gastroenterology 107:1848-1855
7. Nauck M, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W 1993 Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91:301-307
8. Gutnxak M, Orskov C, Holst JJ, Ahrén B, Efendic S 1992 Antidiabetogenic effect of glucagon-like peptide-I (7-36) amide in normal subjects and patients with diabetes mellitus. N Engl Med J 326: 1316-1322
9. Kaplan AM, Vigna SR 1994 Gastric inhibitory polypeptide (GIP) binding sites in rat brain. Peptides 15:297-302
10. Amiranoff B, Vauclin-Jacques N, Laburthe M 1984 Functional GIP receptors in a hamster pancreatic beta-cell line Inlll: specific binding and biological effects. Biochem Biophys Res Commun 123: 671-676
11. Gallwitz B, Witt M, Folsh UR, Creutzfeldt W, Schmidt WE 1993 Binding specificity and signal transduction of receptors for glucagon-like peptide-1 (7-36) amide and gastric inhibitory polypeptide on RINm5F insulinoma cells. J Mol Endocrinol 10:259-268
12. Lu M, Wheeler MB, Leng XH, Boyd III AE 1993 The role of free cytosolic calcium level in β-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide 1(7-37). Endocrinology 132:94-100
13. Wahl MA, Plehn RJ, Landsbeck EA, Verspohl EJ, Ammon HPT 1992 Are ionic fluxes of pancreatic beta cells a target for gastric inhibitory polypeptide? Mol Cell Endocrinol 90:117-123
14. Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI 1993 Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133:2861-2870
15. Polak M, Scharfmann R, Seilheimer B, Eisenbarth G, Dressier D, Verma IM, Potter H 1993 Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line. Dev Biol 90:5781-5785
16. Jia X, Brown JC, Ma P, Pederson RA, McIntosh CHS 1995 The effects of glucose dependent insulinotropic polypeptide and glucagon-like peptide 1 (7-36) on insulin secretion. Am J Physiol 268: E645-E651
17. Brown JC 1971 A gastric inhibitory polypeptide. The amino acid composition and tryptic peptides. Can J Biochem 49:255-261
18. Wheeler MB, Lu M, Dillon JS, Leng X-H, Chen C, Boyd AE 1993 Functional expression of the rat glucagon-like peptide-1 receptor, evidence for coupling to both adenylyl cyclase and phospholipase C. Endocrinology 133:57-62
19. Kieffer TJ, Verchere CB, Fell CD, Huang Z, Brown JC, Pederson RA 1993 Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumor-derived β-cell line (βTC3). Can J Physiol Pharmacol 71:917-922
20. Samama P, Cotecchia S, Costa T, Lefkowitz RJ 1993 A mutation-induced activated state of the β2-adrenergic receptor. J Biol Chem 268:4625-4636
21. Pederson RA, Buchan AMJ, Zahedi-Asl S, Chan CB, Brown JC 1982 Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regul Pept 5:53-63
22. Downey GP, Chan CK, Trudel SA, Grinstein S 1990 Actin assembly in electropermeabilized neutrophils: role for intracellular calcium. J Cell Biol 110:1975-1982
23. 2+ in human neutrophils. J Biol Chem 262: 13558-13566
24. Ohneda A, Ohneda K 1994 Effect of C-terminal fragments of glucagon on insulin secretion in dogs. Metabolism 43:771-775
25. Fehmann HC Jiang J, Schweinfurth J, Wheeler MB, Boyd III AE, Gôke B 1994 Stable expression of the rat GLP-1 receptor in CHO cells: activation and binding characteristics utilizing GLP-1 (7-36)-amide, oxyntomodulin, exendin-4 and exendin (9-39). Peptides 15: 453-456
26. Yasuda K, Inagaki N, Yamada Y, Kubota A, Seino S, Seino Y 1994 Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells: its structure and functional properties. Biochem Biophys Res Commun 205:1556-1562
27. Schmid R, Schusdziarra V, Aulehner R, Weigert N, Classen M 1990 Comparison of GLP-1 (7-36 amide) and GIP on release of somatostatin-like immunoreactivity and insulin from the isolated rat pancreas. Z Gastroenterol 28:280-284
28. Suzuki S, Kawai K, Ohashi S, Mukai H, Murayana Y, Yamashita K 1990 Reduced insulinotropic effects of glucagon-like peptide I-(7— 36)-amide and gastric inhibitory polypeptide in isolated perfused diabetic rat pancreas. Diabetes 39:1320-1325
29. Siegel EG, Schulze A, Schmidt WE, Creutzfeldt W 1992 Comparison of the effect of GIP and GLP-1 (7-36 amide) on insulin release from rat pancreatic islets. Eur J Clin Invest 22:154-157
30. Shima K, Hirota M, Ohboshi C 1988 Effect of glucagon-like peptide-1 on insulin secretion. Regul Pept 22:245-252
31. Usdin TB, Bonner TI, Mezey E 1994 Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Endocrinology 135:2662-2680
32. Patel YC, Srikant CB 1994 Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology 135:2814-2818
33. Gôke R, Just R, Lankat-Buttgereit B, Goke B 1994 Glycosylation of the GLP-1 receptor is a prerequisite for regular receptor function. Peptides 15:675-681
34. Kolligs F, Fehmann HC, Goke R, Gôke B 1995 Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide. Diabetes 44:16-19
35. Wang Z, Wang RM, Owji AA, Smith DM, Ghatei MA, Bloom SR 1995 Glucagon-like peptide-1 is a physiological incretin in rat. J Clin Invest 95:417-421
36. 36amide) in individual ob/ob mouse β-cells. Cell Calcium 15:391-400
37. Widmann C, Bürki E, Dolci W, Thorens B 1994 Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of j3 cell lines. Mol Pharmacol 45:1029-1035
38. Lytton J, Westlin M, Hanley MR 1991 Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 266:17067-17071
39. Abou SA, Juppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT, Kronenberg HM, Segre GV 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736
40. Jelinek LJ, Lok S, Rosenberg GB, Smith RA, Grant FJ, Biggs S, Bensch PA, Kuijper JL, Sheppard PO, Sprecher CA, O'Hara PJ, Foster D, Walker KM, Chen LHJ, McKeman PA, Kindsvogel W 1993 Expression cloning and signaling properties of the rat glucagon receptor. Science 259:1614-1616
41. Houssami S, Findlay DM, Brady CL, Myers DE, Martin TJ, Sexton PM 1994 Isoforms of the rat calcitonin receptor: consequences for ligand binding and signal transduction. Endocrinology 135:183-190
42. Force T, Bonventre JV, Flannery MR, Gom AH, Yamin M, Goldring SR 1992 Cloned porcine renal calcitonin receptor couples to adenylate cyclase and phospholipase C. Am J Physiol 262: F1110-F1115
43. Spengler D, Waeber C, Pantaloni C, Holsboer F, Bockaert J, Seeburg PH, Joumot L 1993 Differential signal transduction by five splice variants of the PACAP receptor. Nature 365:170-175
44. Wakelam HJ, Murphy GJ, Hruby VJ, Houslay MD 1986 Activation of two signal-transduction systems in hepatocytes by glucagon. Nature 323:68-71
45. Holz GG, Kuhtreiber WM, Habener JF 1993 Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-l(7-37). Nature 361:362-365
46. 2+-concentration in rat islets cells. Mol Cell Endocrinol 96:85-90
47. 2+ channel activity. Endocrinology 133:1685-1692
48. in. 76th Annual Meeting of The Endocrine Society Anaheim CA, 1994 (Abstract)
49. Gou J, Abou-Samra AB, Bringhurst FR 1993 Regulation of phosphate and PLC by parathyroid-hormone is selectively modulated by the level of PTH/PTHrP expression in stably transfected LLC-PK1 cells. J Bone Miner Res 8:sl76 (Abstract)
50. Tanizawa Y, Riggs AC, Elbein SC, Whelan A, Donis-Keller H, Permutt MA 1994 Human glucagon-like peptide-1 receptor gene in NIDDM: identification and use of simple sequence repeat polymorphisms in genetic analysis. Diabetes 43:752-757