Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

Journal of Biological Chemistry

Volumn 270, Issue 36, 1995, Pages 21396-21403

  Han, Jeung Whan ^a   Pearson, Richard B ^a   Dennis, Patrick B ^a   Thomas, George ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

1 ETHYL 4 HYDRAZINO 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; METHYLXANTHINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE; PROTEIN KINASE P70; RAPAMYCIN; TACROLIMUS; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

3T3 CELLS; AMINO ACID SEQUENCE; ANDROSTADIENES; ANIMAL; BASE SEQUENCE; BLOOD; IMMUNOSUPPRESSIVE AGENTS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NICOTINIC ACIDS; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHORYLATION; POLYENES; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; TACROLIMUS; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA;

EID: 0029081544     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.36.21396     Document Type: Article

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