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Volumn 51, Issue 6, 1995, Pages 592-595

Taxuspine D, a new taxane diterpene from Taxus cuspidata with potent inhibitory activity against Ca2+-induced depolymerization of microtubules

Author keywords

microtubule depolymerization; Taxoid; Taxus cuspidata; taxuspine D; yew

Indexed keywords

ACETIC ACID DERIVATIVE; CALCIUM ION; DITERPENE; TAXANE DERIVATIVE;

EID: 0029079377     PISSN: 00144754     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/BF02128750     Document Type: Article
Times cited : (50)

References (15)
  • 7
    • 84936098083 scopus 로고    scopus 로고
    • Taxuspine D (1) [α]21D-32.2° (c 0.87, MeOH); IR (film) vmax 3540, 1750, 1710, 1640, 1580, and 1250 cm−1; UV (MeOH) λmax 218(ε 11600), 223 (sh), and 277 nm (14900);1H and13C NMR (table); EIMS m/z (%) 707 (M+−OH, 0.3), 664 (2), 662 (2), 605 (4), 562 (2), 544 (2), 503 (2), 491 (2), 474 (3), 456 (2), 432 (2), 414 (5), 372 (7), 354 (13), 312 (15), 294 (10), and 131 (100); HREIMS m/z 707.3073 (M−OH)+ calcd for C39H47O12, 707.3067.
  • 10
    • 84936093428 scopus 로고    scopus 로고
    • 1H−1H COSY correlations (500 MHz, CDCl3, H/H): 1/2, 2/3, 5/6, 6/7, 9/10, 14/1, 22/23, 25/26, and 26/27
  • 13
    • 84936135891 scopus 로고    scopus 로고
    • NOESY correlations (500 MHz, CDCl3, H/H): 1/2, 1/14a, 1/14b, 1/17, 2/5, 2/16, 2/19, 3/7, 3/10, 3/14a, 3/20a, 5/6, 5/19, 6/7, 7/10, 9/16, 9/19, 10/18, 14a/14b, 14a/20a, 14b/17, 16/17, and 22/25.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.