Functional studies but not receptor binding can distinguish surmountable from insurmountable AT1 antagonism

Journal of Pharmacology and Experimental Therapeutics

Volumn 273, Issue 2, 1995, Pages 753-761

  Panek, R L ^a   Lu, G H ^a   Overhiser, R W ^a   Major, T C ^a   Hodges, J C ^a   Taylor, D G ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; 2 ETHYL 5,7 DIMETHYL 3 [4 [2 (2H TETRAZOL 5 YL)PHENYL]BENZYL]IMIDAZO[4,5 B]PYRIDINE; 2 PROPYL 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 4 (2 TRIFLUOROACETYL 1H PYRROL 1 YL) 1H IMIDAZOLE 5 CARBOXYLIC ACID; 3 [2 BUTYL 1 (4 CARBOXY 2 CHLOROBENZYL) 1H IMIDAZOL 5 YL] 2 (2 THENYL)ACRYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II ANTAGONIST; CI 996; EPROSARTAN; INOSITOL PHOSPHATE; IODINE 125; LOSARTAN POTASSIUM; SARALASIN; SKF 108834; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; LIVER MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; SCATCHARD PLOT; SMOOTH MUSCLE FIBER; THORACIC AORTA;

ANGIOTENSIN I; ANIMAL; AORTA; CELLS, CULTURED; IN VITRO; LIVER; RABBITS; RATS; RECEPTORS, ANGIOTENSIN;

EID: 0029078461     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)