CpG islands and genes

Current Opinion in Genetics and Development

Volumn 5, Issue 3, 1995, Pages 309-314

  Cross, Sally H ^a   Bird, Adrian P ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GUANINE; TRANSCRIPTION FACTOR;

AGING; CARCINOGENESIS; CHROMOSOME BANDING PATTERN; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; GENE ACTIVATION; GENE ISOLATION; GENOME; HUMAN; PRIORITY JOURNAL; RESTRICTION SITE; REVIEW;

ANIMAL; BASE SEQUENCE; CHROMOSOME BANDING; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA; DOSAGE COMPENSATION (GENETICS); GENES; HUMAN; METHYLATION; MICE; SUPPORT, NON-U.S. GOV'T;

EID: 0029075074     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-437X(95)80044-1     Document Type: Article

References (55)

1. CG dinucleotide clusters in MHC genes and in 5′ demethylated genes
2. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
3. Use of restriction endonucleases to detect and isolate genes from mammalian cells
4. Alternative chromatin structure at CpG islands
5. Nonmethylated islands in fish genomes are GC-poor
6. Number of CpG islands and genes in human and mouse
7. How many genes in the human genome?
8. CpG islands as gene markets in the human genome
9. Evidence for erosion of mouse CpG islands during mammalian evolution
10. Direct determination of Notl cleavage sites in the genomic DNA of adult mouse kidney and human trophoblast using whole-range restriction landmark genomic scanning
11. Mammalian chromosome banding—an expression of genome organization
12. Review article: chromosome bands, their chromatin flavors, and their functional features
13. The isochore organization of the human genome
14. The highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes
15. The distribution of CpG islands in mammalian chromosomes
16. Genome linkage scanning: systematic or intelligent?
17. NotI Linking Clones as a Tool for Joining Physical and Genetic Maps of the Human Genome
18. DNA sequence analysis of human chromosome 21 Notl linking clones
19. Isolation of Notl sites from chromosome 22q11
20. Methylation and sequence analysis around Eagi sites: identification of 28 new CpG islands in XQ24-XQ28
21. Somatic cell hybrid panel and Notl linking clones for physical mapping of human chromosome 3
22. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
23. YAC contig organisation and CpG island analysis in Xq28
24. Isolation of a new gene GS2 (DX1283E) from a CpG island between STS and KAL1 on Xp22.3
25. Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae
26. Identification of genes within CpG-enriched DNA from human chromosome 4p16.3
27. Island rescue PCR: a rapid and efficient method for isolating transcribed sequences from yeast artificial chromosomes and cosmids
28. Purification of CpG islands using a methylated DNA binding column
29. In vitro methylation of CpG-rich islands
30. Demethylation of CpG islands in embryonic cells
31. Demethylation of somatic and testis-specific histone H2A and H2B genes in F9 embryonal carcinoma cells
32. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
33. Sp1 elements protect a CpG island from de novo methylation
34. Transcriptonal repression by methylation of CpG
35. X-chromosome inactivation and cell memory
36. In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1
37. High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5′ region on the active and inactive X chromosomes: correlation with binding sites for transcription factors
38. CpG island promoter region methylation patterns of the inactive-X-chromosome hypoxantine phosphoribosyltransferase (Hprt) gene
39. Evidence that random and imprinted Xist expression is controlled by preemptive methylation
40. Imprinted and X-chromosome counting mechanisms determine Xist expression in early mouse development
41. Parental imprinting of autosomal mammalian genes
42. Role for DNA methylation in genomic imprinting
43. Allele-specific methylation and expression of an imprinted U2af1-rs1 (SP2) gene
44. High levels of de novo methylation and altered chromatin structure at CpG islands in celllines
45. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
46. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
47. Progressive de novo methylation at the bcr-abl locus in the course of chronic myelogenous leukemia
48. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
49. Dynamic mutations hit double figures
50. Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE
51. The cloning of FRAXF: trinucleotide repeat expansion and methylation at a third fragile site in distal Xqter
52. Implications of FRA16A structure for the mechanism of chromosomal fragile site genesis
53. Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method
54. A new imprinted gene cloned by a methylation-sensitive genome scanning method
55. Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method