Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

Journal of Neuroscience

Volumn 15, Issue 5 II, 1995, Pages 3775-3787

  Portera Cailliau, Carlos ^a   Hedreen, John C ^a,c   Price, Donald L ^a   Koliatsos, Vassilis E ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

endonuclease; excitotoxicity; Huntington disease; necrosis; neostriatum; programmed cell death

Indexed keywords

BIOTIN; DEOXYURIDINE PHOSPHATE; DNA FRAGMENT; QUINOLINIC ACID; TRANSFERASE;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; DNA STRAND BREAKAGE; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; MALE; NEOSTRIATUM; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029072690     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.15-05-03775.1995     Document Type: Article

References (45)

1. Albin RL, Reiner A, Anderson KD, Dure LS, IV, Handelin B, Balfour R, Whetsell WO, Penney JB, Young AB (1992) Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Ann Neurol 31:425-430.
2. Appel SH (1981) A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease. Ann Neurol 10:499-505.
3. Arends MJ, Morris RG, Wyllie AH (1990) Apoptosis. The role of the endonuclease. Am J Pathol 136:593-608.
4. Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB (1986) Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321:168-171.
5. Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB (1989) Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse 3:38-47.
6. Bursch W, Paffe S, Putz B, Barthel G, Schulte-Hermann R (1990) Determination of the length of the histological stages of apoptosis in normal liver and in altered foci of rats. Carcinogenesis 11:847-853.
7. Chang G-Q, Hao Y, Wong F (1993) Apoptosis: final common pathway of photoreceptor death in rd. rds. and rhodopsin mutant mice. Neuron 11:595-605.
8. Collins RJ, Harmon BV, Gobé GC, Kerr JFR (1992) Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int J Radiat Biol 61:451-453.
9. Coyle JT, Schwarcz R (1976) Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea. Nature 263:244-246.
10. Cudkowicz M, Kowall NW (1990) Degeneration of pyramidal projection neurons in Huntington's disease cortex. Ann Neurol 27:200-204.
11. Deshpande J, Bergstedt K, Linden T, Kalimo H, Wieloch T (1992) Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death. Exp Brain Res 88:91-105.
12. Dunlap CB (1927) Pathologic changes in Huntington's chorea. With special reference to the corpus striatum. Arch Neurol Psychiatry 18: 867-943.
13. Ellis RE, Yuan J, Horvitz HR (1991) Mechanisms and functions of cell death. Annu Rev Cell Biol 7:663-698.
14. Freeman RS, Estus S, Horigome K, Johnson EM Jr (1993) Cell death genes in invertebrates and (maybe) vertebrates. Curr Opin Neurobiol 3:25-31.
15. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
16. Goto K, Ishige A, Sekiguchi K, Iizuka S, Sugimoto A, Yuzurihara M, Aburada M, Hosoya E, Kogure K (1990) Effects of cycloheximide on delayed neuronal death in rat hippocampus. Brain Res 534:299-302.
17. Gwag BJ, Lobner D, Koh J, Wie MB, Choi DW (1994) Blockade of glutamate receptors during oxygen or glucose deprivation unmasks apoptosis in cultured cortical neurons. Soc Neurosci Abstr 20:248.
18. Hedreen JC, Peyser CE, Folstein SE, Ross CA (1991) Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease. Neurosci Lett 133:257-261.
19. Heinsen H, Strik M, Bauer M, Luther K, Ulmar G, Gangnus D, Jungkunz G, Eisenmenger W, Götz M (1994) Cortical and striatal neurone number in Huntington's disease. Acta Neuropathol 88:320-333.
20. Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983.
21. Ignatowicz E, Vezzani A-M, Rizzi M, D'Incalci M (1991) Nerve cell death induced in vivo by kainic acid and quinolinic acid does not involve apoptosis. Neuroreport 2:651-654.
22. Kerr JFR, Harmon BV (1991) Definition and incidence of apoptosis: an historical perspective. In: Apoptosis (Tomei LD, Cope FO, eds), pp 5-29. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
23. Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
24. Kowall NW, Ferrante RJ, Martin JB (1987) Patterns of cell loss in Huntington's disease. Trends Neurosci 10:24-29.
25. Kure S, Tominaga T, Yoshimoto T, Tada K, Narisawa K (1991) Glutamate triggers internucleosomal DNA cleavage in neuronal cells. Biochem Biophys Res Commun 179:39-45.
26. Lange HW (1981) Quantitative changes of telencephalon. diencephalon, and mesencephalon in Huntington's chorea, postencephalitic, and idiopathic parkinsonism. Vehr Anat Ges 75:923-925.
27. McCaughey WTE (1961) The pathologic spectrum of Huntington's chorea. J Nerv Ment Dis 133:91-103.
28. McGeer EG, McGeer PL (1976) Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids. Nature 263:517-519.
29. Obeid LM, Linardic CM, Karolak LA, Hannun YA (1993) Programmed cell death induced by ceramide. Science 259:1769-1771.
30. Oppenheim RW (1991) Cell death during development of the nervous system. Annu Rev Neurosci 14:453-501.
31. Peitsch MC, Polzar B, Stephan H, Crompton T, MacDonald HR, Mannherz HG, Tschopp J (1993) Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J 12:371-377.
32. Pittman RN, Wang S, DiBenedetto AJ, Mills JC (1993) A system for characterizing cellular and molecular events in programmed neuronal cell death. J Neurosci 13:3669-3680.
33. Portera-Cailliau C, Sung C-H, Nathans J, Adler R (1994) Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci USA 91:974-978.
34. Rabacchi SA, Bonfanti L, Liu X-H, Maffei L (1994) Apoptotic cell death induced by optic nerve lesion in the neonatal rat. J Neurosci 14:5292-5301.
35. Reiner A, Albin RL, Anderson KD, D'Amato CJ, Penney JB, Young AB (1988) Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci USA 85:5733-5737.
36. Schwartz LM, Smith SW, Jones MEE, Osborne BA (1993) Do all programmed cell deaths occur via apoptosis? Proc Natl Acad Sci USA 90:980-984.
37. Sotrel A, Paskevich PA, Kiely DK, Bird ED, Williams RS, Myers RH (1991) Morphometric analysis of the prefrontal cortex in Huntington's disease. Neurology 41:1117-1123.
38. Surh CD, Sprent J (1994) T-Cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100-103.
39. Tominaga T, Kure S, Narisawa K, Yoshimoto T (1993) Endonuclease activation following focal ischemic injury in the rat brain. Brain Res 608:21-26.
40. Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis polycystic kidneys and hypopigmented hair. Cell 75:229-240.
41. Vonsattel J-P, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP Jr (1985) Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol 44:559-577.
42. White K, Grether ME, Abrams JM, Young L, Parrell K, Steller H (1994) Genetic control of programmed cell death in Drosophila. Science 677-683.
43. Wood KA, Dipasquale B, Youle RJ (1993) In situ labeling of granule cells for apoptosis-associated DNA fragmentations reveals different mechanisms of cell loss in developing cerebellum. Neuron 11:621-632.
44. Wouterlood FG, Bol JGJM, Steinbusch HWM (1987) Double-label immunocytochemistry: combination of anterograde neuroanatomical tracing with Phaseolus vulgaris leucoagglutinin and enzyme immunocytochemistry of target neurons. J Histochem Cytochem 35:817-823.
45. Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556.