Cerebral metabolic rate and hypothermia: Their relationship with ischemic neurologic injury

Journal of Neurosurgical Anesthesiology

Volumn 7, Issue 3, 1995, Pages 216-221

  Lanier, William L ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Anoxia; Brain; Cerebral ischemia; Cerebral oxygen consumption; Cerebral protection; Hypothermia

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CREATINE PHOSPHATE; GLUCOSE; GLYCOGEN; ION; LACTIC ACID; NEUROTRANSMITTER; PHOSPHOLIPASE; POTASSIUM ION; XANTHINE OXIDASE;

BASAL METABOLIC RATE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN PROTECTION; CARDIOPULMONARY BYPASS; CONFERENCE PAPER; ELECTROENCEPHALOGRAM; HUMAN; HYPOTHERMIA; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

BRAIN; BRAIN ISCHEMIA; HUMAN; HYPOTHERMIA; KINETICS;

EID: 0029072113     PISSN: 08984921     EISSN: 15371921     Source Type: Journal    
DOI: 10.1097/00008506-199507000-00021     Document Type: Article

References (31)

1. Michenfelder JD, Milde JH. The relationship among canine brain temperature, metabolism, and function during hypothermia. Anesthesiology 1991;75:130-6.
2. Michenfelder JD, Milde JH. The effect of profound levels of hypothermia (below 14°C) on canine cerebral metabolism. J Cereb Blood Flow Metab 1992;12:877-80.
3. Levy WJ. Quantitative analysis of EEG changes during hypothermia. Anesthesiology 1984;60:291-7.
4. Michenfelder JD. Anesthesia and the brain: clinical, functional, metabolic, and vascular correlates. New York: Churchill Livingstone, 1988:23-34.
5. Blair E. A physiologic classification of clinical hypothermia Surgery 1965;58:607-18.
6. Antognini JF. Hypothermia eliminates isoflurane requirement at 20°C. Anesthesiology 1993;78:1152-6.
7. Michenfelder JD, Theye RA. The effects of anesthesia and hypothermia on canine cerebral ATP and lactate during anoxia produced by decapitation. Anesthesiology 1970;33: 430-9.
8. Minamisawa H, Smith M-L, Siesjo BK. The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 min of forebrain ischemia. Ann Neurol 1990;28: 26-33.
9. Busto R, Dietrich WD, Globus M Y-T, et al. Small differences in intraischemic brain temperature critically determine the extent of ischemie neuronal injury. J Cereb Blood Flow Metab 1987;7:729-3 8.
10. Natale JE, D’Alecy LG. Protection from cerebral ischemia by brain cooling without reduced lactate accumulation in dogs. Stroke 1989;20:770-7.
11. Kuboyama K, Safar P, Radovsky A, et al. Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs. A prospective, randomized study. Crit Care Med 1993;21:1348-58.
12. Leonov Y, Sterz F, Safar P, et al. Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J Cereb Blood Flow Metab 1990;10:57-70.
13. Collins RC, Dobkin BH, Choi DW. Selective vulnerability of the brain: new insights into the pathophysiology of stroke. Ann Intern Med 1989;110:992-1000.
14. Greeley WJ, Kern FH, Ungerleider RM, et al. The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants, and children. J Thorac Cardiovasc Surg 1991; 101:783-94.
15. Spetzler RF, Hadley MN, Rigamonti D, et al. Aneurysms of the basilar artery treated with circulatory arrest, hypothermia, and barbiturate cerebral protection. J Neurosurg 1988; 68:868-79.
16. Tharion J, Johnson DC, Celermajer JM, et al. Profound hypothermia with circulatory arrest: nine-years’ clinical experience. J Thorac Cardiovasc Surg 1982;84:66-72.
17. Harper JA. Review of physiological chemistry, 14th ed. Los Altos, CA: Lange Medical Publishers, 1973:138.
18. Pulsinelli WA, Brierley JB. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 1979;10: 267-72.
19. Hofer RE, Christopherson TJ, Scheithauer BW, et al. The effect of a platelet activating factor antagonist (BN 52021) on neurologic outcome and histopathology in a canine model of complete cerebral ischemia. Anesthesiology 1993;79:347-53.
20. Miller JR, Myers RE. Neuropathology of systemic circulatory arrest in adult monkeys. Neurology 1972;22:888-904.
21. Nemoto EM, Bleyaert AL, Stezoski SW, et al. Global brain ischemia: a reproducible monkey model. Stroke 1977;8:558-64.
22. Michenfelder JD, Milde JH. Faüure of prolonged hypocap-nia, hypothermia, or hypertension to favorably alter stroke in primates. Stroke 1977;8:87-91.
23. Steen PA, Soule EH, Michenfelder JD. Detrimental effect of prolonged hypothermia in cats and monkeys with and without regional cerebral ischemia. Stroke 1979;10:522-9.
24. Steen PA, Milde JH, Michenfelder JD. The detrimental effects of prolonged hypothermia and rewarming in the dog. Anesthesiology 1980;52:224-30.
25. Fay T. Early experiences with local and generalized refrigeration of the human brain. J Neurosurg 1959;16:239-60.
26. Ridenour TR, Warner DS, Todd MM, et al. Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats. Stroke 1992;23:733-8.
27. Warner DS, McFarlane C, Todd MM, et al. Sevoflurane and halothane reduce focal ischemic brain damage in the rat: possible influence on thermoregulation. Anesthesiology 1993;79:985-92.
28. Wass CT, Lanier WL, Hofer RE, et al. Temperature increases of ⩾1°C worsen functional neurologic outcome and histopathology in a canine model of complete cerebral ischemia. J Neurosurg Anesthesiol 1994;6:305.
29. Drummond JC, Shapiro HM. In: Miller RD, ed. Cerebral physiology. Anesthesia, 3rd ed. New York: Churchill Livingstone, 1990:624.
30. Busto R, Globus M Y-T, Dietrich WD, et al. Effect of mild hypothermia on ischemia-induced release of neurotransmit-ters and free fatty acids in rat brain. Stroke 1989, 20:904-10.
31. Milde LN, Weglinski MR. Pathophysiology of metabolic brain injury. In: Cottrell JE, Smith DS, eds. Anesthesia and Neurosurgery, 3rd ed. St. Louis: Mosby, 1994:59-92.