Metabolic coupling factors in pancreatic β-cell signal transduction

Annual Review of Biochemistry

Volumn 64, Issue , 1995, Pages 689-719

  Newgard, Christopher B ^a   Denis McGarry, J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

glucose; glucose phosphorylation; hyperlipidemia; insulin; cell dysfunction

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL; FATTY ACID; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; MALONYL COENZYME A; POTASSIUM CHANNEL;

ESTERIFICATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; HYPERLIPIDEMIA; INSULIN RELEASE; LIPID METABOLISM; MITOCHONDRIAL RESPIRATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PHOSPHORYLATION; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0029071517     PISSN: 00664154     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.bi.64.070195.003353     Document Type: Review

References (161)

1. Unger RH. 1981. Diabetologia 20:1-11
2. Beltran del Rio H, Schnedl W, Ferber S, Newgard CB. 1994. In Pancreatic Islet Transplantation, ed. W Chick, R Lanza. 1:169-183. Austin: Landes
3. Lacy PE, Scharp DW. 1986. Annu. Rev. Med 37:33-46
4. Newgard CB. 1992. Bio-Technology 10: 1112-20
5. Johnson JH, Ogawa A, Chen L, Orci L, Newgard CB, et al. 1990. Science 250: 546-19
6. Pfeiffer MA, Halter JB. Porte D Jr. 1981. Am. J. Med. 70:579-88
7. Sener A, Malaisse-Lagae F, Malaisse WJ. 1981. Proc. Natl. Acad. Sci. USA 78:5460-64
8. MacDonald MJ, McKenzie DI, Kaysen JH, Walker TM, Moran SM, et al. 1991. J. Biol. Chem. 266:1335-40
9. Sener A, Blachier F, Rasschaert J, Malaisse WJ. 1990. Endocrinology 127: 107-13
10. Schmidt HHW, Warner TD, Ishii K, Sheng H, Murad F. 1992. Science 255: 721-23
11. Laychock SG, Modica ME, Cavanaugh CT. 1991. Endocrinology 129:3043-52
12. Charles S, Tamagawa T, Henquin JC, 1982. Biochem. J. 208:301-9
13. Henquin JC, Meissner HP. 1981. Am. J. Physiol. 240:E245-50
14. Liang Y, Matschinsky FM. 1994. Annu. Rev. Nutr. 14:59-81
15. Orskov C. 1992. Diabetologia 35:701-11
16. Thorens B, Waeber G. 1993. Diabetes 42:1219-25
17. Grodsky GM, Batts AA, Bennett LL, Vcella C, McWilliams NB, Smith DF. 1963. Am. J. Physiol. 205:638-44
18. Ashcroft SJH. 1981. In The Islets of Langherhans, ed. SJ Cooperstein, D Watkins, pp. 117-48. London: Academic
19. Coore HG, Randle PJ, Simon E, Kraicer PF, Shelesnyak MC. 1963. Nature 197: 1264-66
20. Malaisse WJ, Sener A, Herchuelz A, Hutton JC. 1979. Metabolism 28:373-86
21. Matschinsky FM, Ellerman JE. 1968. J. Biol. Chem. 243:2730-36
22. Landgraf R, Kotler-Brajtburg J, Matschinsky FM. 1971. Proc. Natl. Acad. Sci. USA 68:546-40
23. Meglasson MD, Matschinsky FM. 1986. Diabetes/Metab.Rev. 2:163-214
24. Hedeskov CJ. 1980. Physiol. Rev. 60: 442-508
25. MacDonald MJ. 1990. Diabetes 29: 1461-66
26. Prentki M, Matschinsky, FM. 1987. Physiol. Rev. 67:1185-248
27. Turk J, Wolf BA, McDaniel ML. 1987. Prog. Lipid Res. 26:125-81
28. Johnson JH, Newgard CB, Milburn JL, Lodish HF, Thorens B. 1990. J. Biol. Chem. 265:6548-51
29. Thorens B, Sarkar HK, Kaback HR, Lodish HF. 1988. Cell 55:281-90
30. Iynedjian PB, Pilot P-R, Nouspikel T, Milburn JL, Quaade C, et al. 1989. Proc. Natl. Acad. Sci. USA 86:7838-42
31. Magnuson MA, Shelton KD. 1989. J. Biol. Chem. 264:15936-42
32. Waddell ID, Burchell A. 1988. Biochem. J. 255:471-76
33. Malaisse WJ, Sener A, Koser M, Ravazzola M, Malaisse-Lagae F. 1977. Biochem. J. 164:447-554
34. Ashcroft SJH, Weerasinghe LCC, Bassett JM, Randle PJ. 1972. Biochem. J. 126:525-32
35. Trus MD, Zawalich WS, Burch PT, Berner DK, Weill VA, et al. 1981. Diabetes 30:911-22
36. Coore HG, Randle PJ. 1964. Biochem. J. 91:56-59
37. Wilson JE. 1984. In Regulation of Carbohydrate Metabolism, pp. 45-85. Boca Raton: CRC
38. Meglasson MD, Burch PT, Hoenig M, Chick WL, Matschinsky FM. 1981. Proc. Natl. Acad. Sci. USA 80:85-89
39. Hughes SD, Johnson JH, Quaade C, Newgard CB. 1992. Proc. Natl. Acad. Sci. USA 89:688-92
40. Giroix M-H, Sener A, Pipeleers DG, Malaisse WJ. 1984. Biochem. J. 223: 447-53
41. Froguel P, Vaxillaire M, Sun F, Vehlo G, Zouali H, et al. 1992. Nature 356: 162-64
42. Froguel P, Zouali H, Vionnet N, Velho G, Vaxillaire M, et al. 1993. N. Engl. J. Med. 328:697-702
43. Byrne MM, Sturis J, Clement K, Vionnet N, Pueyo ME, et al. 1994. J. Clin. Invest. 93:1120-30
44. Vehlo G, Froguel P, Clement K, Pueyo ME, Rakotoambinina B, et al. 1992. Lancet 340:444-48
45. Gidh-Jain M, Takeda J, Xu LZ, Lange AJ, Vionnet N, et al. 1993. Proc. Natl. Acad. Sci. USA 90:1932-36
46. Efrat S, Leiser M, Wu Y-J, Fusco-DeMane D, Emran OA, et al. 1994. Proc. Natl. Acad. Sci. USA 91:2051-55
47. Becker TC, BeltrandelRio H, Noel RJ, Johnson JH, Newgard CB. 1994. J. Biol. Chem. 269:21234-38
48. Becker TC, Noel RJ, Coats WS. Gomez-Foix AM, Alam T, et al. 1994. Methods Cell Biol. 43:161-89
49. German MS. 1993. Proc. Natl. Acad. Sci. USA 90:1781-85
50. Epstein PN, Boschero AC, Atwater I, Cai XG, Overbeek PA. 1992. Proc. Natl. Acad. Sci. USA 89:12038-42
51. Voss-McCowan ME, Xu B, Epstein PN. 1994. J. Biol. Chem. 269:15814-18
52. Gazdar AF, Chick WL, Oie HK, Sims HL, King DL, et al. 1980. Proc. Natl. Acad. Sci. USA 77:3519-23
53. Halban PA, Praz GA, Wollheim CB. 1983. Biochem. J. 212:439-43
54. Clark SA, Burnham BL, Chick WL. 1990. Endocrinology 127:2779-88
55. Efrat S, Linde S, Kofod H, Spector D, Delannoy M, et al. 1988. Proc. Natl. Acad. Sci. USA 85:9037-41
56. Miyazaki J-I, Araki K, Yamato E, Ikegami H, Asano T, et al. 1990. Endocrinology 127:126-32
57. Efrat S, Leiser M, Surana M, Tal M, Fusco-Demane D, et al. 1993. Diabetes 42:901-7
58. Hazen SL, Wolf MJ, Ford DA, Gross RW. 1994. FEBS Lett. 339:213-16
59. Whitesell RR, Powers AC, Regen DM, Abumrad NA. 1991. Biochemistry 30: 11560-66
60. Asfari M, Janjic D, Meda P, Li G, Halban PA, et al. 1992. Endocrinology 130:167-78
61. Ishihara H, Asano T, Katsunori T, Katagiri H, Inukai K, et al. 1994. J. Biol. Chem. 269:3081-87
62. Ferber S, BeltrandelRio H, Johnson JH, Noel RJ, Cassidy LE, et al. 1994. J. Biol. Chem. 269:11523-29
63. Newgard CB. 1994. Diabetes 43:341-50
64. Newgard CB, Ferber S, Quaade C, Johnson JH, Hughes SD. 1994. See Ref. 161, pp. 119-53
65. Permutt MA, Koryani L, Keller K, Lacy PE, Scharp DW, et al. 1989. Proc. Natl. Acad. Sci. USA 86:8688-92
66. Newgard CB, Quaade C, Hughes SD, Milburn JL. 1990. Biochem. Soc. Trans. 18:851-53
67. Unger RH. 1991. Science 251:1200-5
68. Orci L, Ravazzola M, Baetens D, Inman L, Amherdt M. 1990. Proc. Natl. Acad. Sci. USA 87:9953-57
69. Thorens B, Wu Y-J, Leahy JL, Weir GC. 1992. J. Clin. Invest. 90:77-85
70. Ohneda M, Johnson JH, Inman LR, Chen L, Suzuki K, et al. 1993. Diabetes 42:1065-72
71. Thorens B, Weir GC, Leahy JL, Lodish HF, Bonner-Weir S. 1990. J. Clin. Invest. 86:1615-22
72. Ogawa A, Johnson JH, Ohneda M, McAllister CT, Inman L, et al. 1992. J. Clin. Invest. 90:497-504
73. Tal M, Wu Y-J, Leiser M, Surana M, Lodish H, et al. 1992. Proc. Natl. Acad. Sci. USA 89:5744-48
74. Tal M, Liang Y, Najafi H, Lodish HF, Matschinsky FM. 1992. J. Biol. Chem. 267:17241-47
75. Chen C, Thorens B, Bonner-Weir S, Weir GC, Leahy J. 1992. Diabetes 41: 1320-27
76. Liang Y, Bonner-Weir S, Wu Y-J, Berdanier CD, Berner DK, et al. 1994. J. Clin. Invest. 93:2473-81
77. Mueckler M, Kruse M, Strube M, Riggs AC, Chin KC, et al 1994. J. Biol. Chem. 269: 17232-35
78. Chen L, Alam T, Johnson JH, Hughes S, Newgard CB, Unger RH. 1990. Proc. Natl. Acad. Sci. USA 87:4088-92
79. Giroix M-H, Baetens D, Rasschaert J, Leclercq-Meyer V, Sener A, et al. 1992. Endocrinology 130:2634-40
80. Milburn JL Jr, Hirose H, Lee YH, Nagasawa Y, Ogawa A, et al. 1995. J. Biol. 270:1295-99
81. Khan A, Chandramouli V, Ostenson CG, Low H, Landau BR, et al. 1990. Diabetes 39:456-59
82. Sekine N, Cirulli V, Regazzi R, Brown LJ, Gine E, et al. 1994. J. Biol. Chem. 269:4895-902
83. Tiedge M, Hohne M, Lenzen S. 1993. Biochem. J. 296:113-18
84. Hughes SD, Quaade C, Johnson JH, Ferber S, Newgard CB. 1993. J. Biol. Chem. 268:15205-12
85. Ashcroft FM, Harrison DE Ashcroft SJH. 1984. Nature 312:446-48
86. Cook DL, Hales CN. 1984. Nature 311: 271-73
87. Misler S, Falke LC, Gillis K, McDaniel ML. 1986. Proc. Natl. Acad Sci. USA 83:7119-23
88. Boyd AE III. 1992. J. Cell. Biochem. 48:234-41
89. MacDonald MJ, Fahien LA. 1990 Arch Biochem. Biophys. 279:104-8
90. Malaisse WJ, Kawazu S, Herchuelz A, Hutton JC, Somers G, et al. 1979. Arch. Biochem. Biophys. 194:49-62
91. Sener A, Kawazu S, Hutton JC, Boschero AC, Devis G, et al. 1978 Biochem. J. 176:217-32
92. Ghosh A, Ronner P, Cheong E, Khalid P, Matschinsky FM. 1991. J. Biol. Chem. 266:22887-92
93. Holz GG, Kuhtreiber WM, Haebner JF. 1993. Nature 361:362-65
94. Turk J, Gross RW, Ramanadham S. 1993. Diabetes 42:367-74
95. Kowluru A, Metz SA. 1994. See Ref. 161, pp. 249-83
96. Takasawa S, Nata K, Yonekura H, Okamoto H. 1993. Science 259:370-73
97. Hutton JC, Sener A, Herchuelz A, Atwater I, Kawazu S, et al. 1980. Endocrinology 106:203-19
98. MacDonald MJ, Fahien LA. 1988. Diabetes 37:997-99
99. Dukes ID, McIntyre MS, Mertz RJ, Philipson LH, Roe MW, et al. 1994. J. Biol. Chem. 269:10979-82
100. MacDonald MJ. 1981. J. Biol. Chem. 256:8287-90
101. MacDonald MJ. 1982. Arch. Biochem. Biophys. 213:643-49
102. MacDonald MJ, Kaysen JH, Moran SM, Pomije CE. 1991. J. Biol. Chem. 266: 22392-97
103. Dean PM, Matthews EK. 1970. J. Physiol. 210:255-64
104. Longo EA, Tornheim K, Deeney JT, Varnum BA, Tillotson D, et al. 1991. J. Biol. Chem. 266:9314-19
105. Rorsman P, Trube G. 1985. Pfluegers Arch. 405:305-9
106. Dunne MJ, Petersen OH. 1986. FEBS Lett. 208:59-62
107. Hopkins WF, Fatherazi S, Peter-Riesch B, Corkey BE, Cook DL. 1992. J. Membr. Biol. 129:287-95
108. Cook DL, Satin LS, Ashford MLJ, Hales CN. 1988. Diabetes 37:495-98
109. Nichols CG, Lederer WJ. 1990. J. Physiol. 423:91-110
110. Weiss JN, Lamp ST. 1987. Science 238: 67-69
111. Gembal M, Gilon P, Henquin J-C. 1992. J. Clin. Invest. 89:1288-95
112. Gembal M, Detimary P, Gilon P, Gao Z-Y, Henquin J-C. 1993. J. Clin. Invest. 91:871-80
113. Seino S, Chen L, Seino M, Blondel O, Takeda J, et al. 1992, Proc. Natl. Acad. Sci. USA 89:584-88
114. Duchen MR, Smith PA, Ashcroft FM. 1993. Biochem. J. 294:35-42
115. Smith PA, Rorsman P, Ashcroft FM. 1989. Nature 342:550-53
116. Gross RW, Ramanadham S, Kruszka KK, Han X, Turk J, 1993. Biochemistry 32:327-36
117. Mignery GA, Sudhof TC. 1990. EMBO J. 9:3894-98
118. Islam MS, Larsson O, Berggren P-O. 1993. Science 262:584-85
119. Worley JF, McIntyre MS, Spencer B, Mertz RJ, Roe MW, et al. 1994. J. Biol. Chen. 269:14359-62
120. Goberna R, Tamarit J Jr, Osorio J, Fussganger R, Tamarit J, el al. 1974. Horm. Metab. Res. 6:256-60
121. Madison LL, Seyffert WA Jr, Unger RH, Barker B. 1968. Metabolism 17: 301-4
122. Malaisse WJ, Malaisse-Lagae F. 1968, J, Lab. Clin. Med. 72:438-48
123. Greenough WB II, Crespin SR, Steinberg D. 1967. The Lancet 115: 1334-36
124. Berne C. 1975. Biochem. J. 152:661-66
125. Berne C. 1975. Biochem. J. 152:667-73
126. Tamarit-Rodriguez J, Vara E, Tamarit J. 1984. Horm. Metab. Res. 16:115-19
127. Tamarit-Rodriguez J, Vara E, Tamarit J. 1984. Biochem. J. 221:317-24
128. Bedoya FJ, Ramirez R, Arilla E, Goberna R. 1984. Diabetes 33:858-63
129. Vara E, Tamarit-Rodriguez J. 1986. Endocrinology 119:404-7
130. Vara E, Tamarit-Rodriguez J. 1986. Metabolism 35:266-71
131. Corkey BE, Glennon MC, Chen KS, Deeney JT, Matschinsky FM, Prentki M. 1989. J. Biol. Chem. 264:21608-12
132. McGarry JD, Foster DW. 1980. Annu. Rev. Biochem. 49:395-420
133. McGarry JD, Mannaerts GP, Foster DW. 1977, J. Clin. Invest. 60:265-70
134. Duan C, Winder WW, 1992. J. Appl. Physiol. 72:901-4
135. Saddik M, Gamble J, Witters LA, Lopaschuk CD. 1993. J. Biol. Chem. 263:25836-45
136. Shrago E, MacDonald MJ, Woldegiorgis G, Bremer J, Schalinske K. 1985. In Clinical Aspects of Human Carnitine Deficiency, ed. P Borum, pp. 28-37. Oxford: Pergamon
137. McGarry JD, Woeltje KF, Kuwajima M, Foster DW. 1989. Diabetes/Melab. Rev. 5:271-84
138. Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, et al. 1992. J. Biol. Chem. 267:5802-10
139. Brun T, Roche E, Kim K, Prentki M. 1993. J. Biol. Chem. 268:18905-11
140. Chen S, Ogawa A, Ohneda M, Unger RH, Foster DW, McGarry JD. 1994. Diabetes 43:878-83
141. Vara E, Fernandez-Martin O, Garcia C, Tamarit-Rodriguez J. 1988. Diabetologia 31:687-93
142. Deeney JT, Tornheim K, Korchak HM, Prentki M, Corkey BE. 1992. J. Biol. Chem. 267:19840-45
143. Planner N, Orci L, Glick BS, Amherdt M, Arden SR, et al. 1989. Cell 59:95-102
144. Declercq PE, Falck JR, Kuwajima M, Tyminski H, Foster DW, et al. 1987. J. Biol. Chem. 262:9812-21
145. MacDonald MJ, Kowluru A. 1985. Diabetes 31:566-70
146. Penn EJ, Brocklehurst KW, Sopwith AM, Hales CN, Hutton JC. 1982. FEBS Lett. 139:4-8
147. Colca JR, Katagal N, Lacy PE, McDaniel ML. 1983. Biochem. J. 212:819-27
148. Metz SA. 1988. Diabetes 37:3-7
149. Wollheim CB, Regazzi R. 1991. FEBS Lett. 268:376-80
150. Calle, R, Ganesan S, Smallwood JI, Rasmussen H. 1992. J. Biol. Chem. 267: 18723-27
151. Ganesan S, Calle R, Zawalich K, Greenawalt K, Zawalich W, 1992. J. Cell Biol. 119:313-24
152. DeFronzo RA, Bonadonna RC, Ferrannini E. 1992, Diabetes Care 15:318-68
153. McGarry JD. 1992. Science 258:766-70
154. McGarry JD. 1994. J. Cell. Biochem. 55S:29-38
155. Reaven GM, Hollenbeck C, Jeng C-Y, Wu MS, Chen Y-DI. 1988. Diabetes 37:1020-24
156. Sako Y, Grill VE, 1990. Endocrinology 1580-89
157. Elks ML. 1993. Endocrinology 133: 208-14
158. Zhou Y-P, Grill VE. 1994. J. Clin. Invest. 93:870-76
159. Pieber TR, Stein DT, Ogawa A, Alam T, Ohneda M, et al. 1993. Am. J. Physiol. 265:E446-53
160. Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, et al. 1994. Proc. Natl. Acad. Sci. USA. 91:10878-82
161. Draznin B, LeRoith D, eds. 1994. Molecular Biology of Diabetes. Totowa, NJ: Humana