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Volumn 5, Issue 14, 1995, Pages 1509-1512

Growth inhibitory effect of naphthofuran and naphthofuranquinone derivatives on Trypanosoma cruzi epimastigotes

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTOZOAL AGENT; BENZNIDAZOLE; FURAN DERIVATIVE; NAPHTHOFURAN DERIVATIVE; NAPHTHOFURANQUINONE DERIVATIVE; NIFURTIMOX; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0029071261     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(95)00248-R     Document Type: Article
Times cited : (71)

References (23)
  • 14
    • 84921202829 scopus 로고    scopus 로고
    • All new compounds show analytical and spectral (IR, NMR, MS) data in full accord with the indicated structures. Details of the synthetic work will be published separately.
  • 15
    • 84921202828 scopus 로고    scopus 로고
    • 6 epimastigotes/ml and the compounds at the stated concentrations were incubated in 24 well tissue culture plates (LINBRO, Flow Laboratories) at a final volume of 1.25 ml/well, in triplicate. Controls without drug, with DMSO (0.4%), with nifurtimox and with benznidazole, were run in parallel. The plates were incubated at 28°C for 96h. After this period the parasite number was determined by an electronic cell counter (Coulter Electronics Inc. Hialeah, FLA, USA, Model D2) and the growth rate determined and compared with the non-treated controls.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.