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Volumn 19, Issue 2, 1995, Pages 227-250

Alpha-lipoic acid as a biological antioxidant

Author keywords

a Lipoic acid; Antioxidant; Dihydrolipoate; Dihydrolipoic acid; Free radicals; Oxidative stress; Redox regulation; Review; Thioctic acid; Lipoate

Indexed keywords

ANTIOXIDANT; DIHYDROLIPOATE; FREE RADICAL; THIOCTIC ACID;

EID: 0029070687     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(95)00017-R     Document Type: Review
Times cited : (1801)

References (158)
  • 2
    • 0000820017 scopus 로고
    • The chemistry and function of lipoic acids
    • (1957) Adv. Enzymol. , vol.18 , pp. 319-347
    • Reed1
  • 5
    • 0018338513 scopus 로고
    • Biosynthesis of lipoic acid via unsaturated fatty acids
    • (1979) Meth. Enzymol. , vol.62 , pp. 152-158
    • Carreau1
  • 15
  • 22
    • 0024208540 scopus 로고
    • Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation
    • (1988) Biochim. Biophys. Acta. , vol.963 , pp. 558-561
    • Bast1    Haenen2
  • 25
    • 0000561914 scopus 로고
    • α-Ketoglutaric dehydrogenase. 8. Isolation and some properties of a flavoprotein component
    • (1960) J. Biol. Chem. , vol.235 , pp. 2485-2491
    • Searls1    Sanadi2
  • 27
    • 0014139748 scopus 로고
    • The standard redox potential of cysteine-cystine from the thiol-disulphide exchange reaction with glutathione and lipoic acid
    • (1967) Eur. J. Biochem. , vol.2 , pp. 327-331
    • Jocelyn1
  • 29
    • 0025233534 scopus 로고
    • Mechanism of the reaction of ebselen with endogenous thiols: Dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen
    • (1990) Mol. Pharmacol. , vol.37 , pp. 412-422
    • Haenen1    de Rooij2    Vermeulen3    Bast4
  • 30
    • 33845377125 scopus 로고
    • 2- (n = 2,4) in aqueous media from irons, salts, thiols, and sulfur, sulfide, or thiosulfate plus rhodanese
    • (1985) Inorg. Chem. , vol.24 , pp. 4331-4335
    • Bonomi1    Werth2    Kurtz3
  • 32
    • 0023040732 scopus 로고
    • Removal of ferritin-bound iron by DL-dihydrolipoate and DL-dihydrolipoamide
    • (1986) Eur. J. Biochem. , vol.155 , pp. 295-300
    • Bonomi1    Pagani2
  • 35
    • 0020074850 scopus 로고
    • Autoxidation of biological molecules: I. The antioxidant activity of vitamin E and related chain-breaking phenolic antioxidant in vitro
    • (1981) J. Am. Chem. Soc. , vol.103 , pp. 6472-6477
    • Burton1    Ingold2
  • 48
    • 0026509008 scopus 로고
    • The reactivity of thiols and disulfides with different redox states of myoglobin: Redox and addition reactions and formation of thiyl radical intermediates
    • (1992) J. Biol. Chem. , vol.267 , pp. 1680-1688
    • Romero1    Ordonez2    Arduini3    Cadenas4
  • 49
    • 0025941730 scopus 로고
    • Biological thiols elicit prolactin proteolysis by glandular kallikrein and permit regulation by biochemical pathways linked to redox control
    • (1991) Biochemistry , vol.30 , pp. 7666-7672
    • Hatala1    Dipippo2    Powers3
  • 51
    • 0018723651 scopus 로고
    • Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide
    • (1979) J. Biol. Chem. , vol.254 , pp. 9627-9632
    • Holmgren1
  • 54
    • 0027217531 scopus 로고
    • Oxidoreductive regulation of nuclear factor kB: Involvement of a cellular reducing catalyst thioredoxin
    • (1993) J. Biol. Chem. , vol.268 , pp. 11380-11388
    • Hayashi1    Ueno2    Okamoto3
  • 57
    • 0026042577 scopus 로고
    • kB-Specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation
    • (1991) New Biol. , vol.3 , pp. 987-996
    • Molitor1    Ballard2    Greene3
  • 60
    • 0027217531 scopus 로고
    • Oxidoreductive regulation of nuclear factor kappa B: Involvement of a cellular reducing catalyst thioredoxin
    • (1993) J. Biol. Chem. , vol.268 , pp. 11308-11380
    • Hayashi1    Ueno2    Okamoto3
  • 64
    • 0021868736 scopus 로고
    • Suppression of tumor promoter-induced chemiluminescence in mouse epidermal cells by several inhibitors of arachidonic acid metabolism
    • (1985) Cancer Res. , vol.45 , pp. 3130-3136
    • Fischer1    Adams2
  • 66
    • 0023194380 scopus 로고
    • Effects of the protein kinase C inhibitor H-7 and calmodulin antagonist W-7 on superoxide production in growing and resting human histiocytic leukemia cells (U937)
    • (1987) Biochem. Biophys. Res. Comm. , vol.144 , pp. 1317-1323
    • Shibanuma1    Kuroki2    Nose3
  • 67
    • 0026981069 scopus 로고
    • Inhibitory effects of antipromoters and radical scavengers on the promotion process in two-stage cell transformation
    • (1992) Tohoku J. Exptl. Med. , vol.168 , pp. 133-136
    • Semba1    Inui2    Yamada3
  • 75
    • 0021751342 scopus 로고
    • Lipoic acid and diabetes: Effect of dihydrolipoic acid administration in diabetic rats and rabbits
    • (1984) J. Biosci. , vol.6 , pp. 37-46
    • Natraj1    Gandhi2    Menon3
  • 77
  • 82
    • 0014938472 scopus 로고
    • Effect of D,L-alpha lipoic acid on the citrate concentration and phosphofructokinase activity of perfused hearts from normal and diabetic rats
    • (1970) Biochem. Biophys. Res. Commun. , vol.41 , pp. 555-561
    • Singh1    Bowman2
  • 86
    • 0025267074 scopus 로고
    • Effects of phenylarsine oxide on stimulation of glucose transport in rat skeletal muscle
    • (1990) Am. J. Physiol. , vol.258 , pp. C648-C653
    • Henriksen1    Holloszy2
  • 88
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes1
  • 94
    • 0026703165 scopus 로고
    • Lipoprotein glycation and its metabolic consequences
    • (1992) Diabetes , vol.41 , pp. 67-73
    • Lyons1
  • 97
    • 0025863547 scopus 로고
    • Oxygen free radical effects in sciatic nerve in experimental diabetes
    • (1991) Diabetes , vol.40 , pp. 873-877
    • Low1    Nickander2
  • 104
    • 84921173660 scopus 로고
    • Modeling cortical cataractogenesis 17: In vitro effect of a-lipoic acid on glucose-induced lens membrane damage, a model of diabetic cataractogenesis
    • submitted
    • (1994) Exptl. Eye Res.
    • Kilic1    Packer2    Trevethick3
  • 105
    • 0027428582 scopus 로고
    • The role of anti-oxidative treatment of diabetes mellitus
    • (1993) Diabetologia , vol.36 , pp. 1212-1213
    • Packer1
  • 106
  • 113
  • 116
    • 0014946619 scopus 로고
    • Sperimentazione clinica di un complesso coenzymatico in epatopazienti
    • (1970) Cl. Terap. , vol.52 , pp. 267-280
    • Bani1
  • 117
    • 0014504304 scopus 로고
    • Einfluss von Conenzym A, Nicotinamid-adenin-dinucleotid (NAD), a-Liponsèure und Cocar☐ylase auf die akute Hepatits (Doppelblindversuch)
    • (1969) Int. J. Clin. Pharmacol. , vol.2 , pp. 133-138
    • Colombi1    Thülen2    Huber3
  • 118
    • 0017089251 scopus 로고
    • Ein Beitrag zur Behandlung chronischer Lebererkrankungen
    • (1976) Med. Klin. , vol.71 , pp. 1831-1835
    • Müller1    Schmitt2
  • 119
    • 0020407859 scopus 로고
    • Treatment of alcohol-related liver disease with thioctic acid: A six month randomised double-blind trial
    • (1982) Gut , vol.23 , pp. 1088-1093
    • Marshall1    Graul2    Morgan3    Sherlock4
  • 121
    • 0023089510 scopus 로고
    • Inhibition of early events in the human T-lymphocyte response to mitogens and alloantigens by hydrogen peroxide
    • (1987) Arch. Surg. , vol.122 , pp. 99-104
    • Freed1    Rapoport2    Lempert3
  • 122
    • 84921173659 scopus 로고    scopus 로고
    • Aune, T. M.; Pierce, C. W. Conversion of soluble immune response suppressor to
  • 123
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • (1985) Science , vol.227 , pp. 375-381
    • Cerutti1
  • 129
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide: General properties and the effect of hyperbaric oxygen
    • (1973) Biochem. J. , vol.134 , pp. 707-716
    • Boveris1    Chance2
  • 132
    • 0018393931 scopus 로고
    • NADH- and NADPH-dependent formation of superoxide amines by bovine heart submitochondrial particles
    • (1979) Biochem. J. , vol.180 , pp. 129-135
    • Takeshige1    Minakami2
  • 138
  • 141
    • 0028349046 scopus 로고
    • The endogenous cofactors, thioctic acid and dihydrolipoic acid, are neuroprotective against NMDA and malonic acid lesions of striatum
    • (1994) Neurosci. Lett. , vol.171 , pp. 17-20
    • Greenamyre1    Garcia-Osuna2    Greene3
  • 142
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi1
  • 146
    • 0023196326 scopus 로고
    • Cigarette smoke and the involvement of free radical reactions in chemical carcinogenesis
    • (1987) Br. J. Cancer. Suppl. , vol.85 , pp. 19-23
    • Pryor1
  • 148
    • 0025866304 scopus 로고
    • Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma: Protective effects of ascorbic acid
    • (1991) Biochem. J. , vol.277 , pp. 133-138
    • Frei1    Forte2    Ames3    Cross4
  • 156
    • 0021036374 scopus 로고
    • Uso del acido tioctico para la prevention de los efectos secondarios provacodos por el benznidazol en pacientes con infeccion de Chaga chronica
    • (1983) Medicina (Buenos Aires) , vol.43 , pp. 285-290
    • Carpintero1
  • 157
    • 84921173658 scopus 로고    scopus 로고
    • Asta Medica, α-Lipoic acid prescribing information.
  • 158
    • 37049062591 scopus 로고
    • Reversal of selective toxicity of (-)-a-lipoic acid by thiamine in thiamine-deficient rats
    • (1965) Nature , vol.207 , pp. 535
    • Gal1


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