Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens

Brain Research

Volumn 683, Issue 2, 1995, Pages 264-269

  Smith, Jason A ^a   Qiu Mo, ^a   Guo, Hongzhi ^a   Kunko, Paul M ^a   Robinson, Susan E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Aspartate; Cocaine; Glutamate; Microdialysis; Nucleus accumbens; Stereotypy

Indexed keywords

ASPARTIC ACID; COCAINE; GLUTAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; STEREOTYPY;

ANALYSIS OF VARIANCE; ANIMAL; ASPARTIC ACID; BEHAVIOR, ANIMAL; CALCIUM; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; MALE; MICRODIALYSIS; NARCOTICS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS; SUPPORT, U.S. GOV'T, P.H.S.; TETRODOTOXIN;

EID: 0029070344     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)00383-2     Document Type: Article

References (20)

1. 3H]GABA
2. Effects of excitatory amino acids on locomotor activity after bilateral microinjection into the rat nucleus accumbens: possible dependence on dopaminergic mechanisms
3. Synthesis and release of amino acid neurotransmitters
4. Drugs of abuse: anatomy, pharmacology and function of reward pathways
5. Intravenous gestational cocaine in rats: Effects on offspring development and weanling behavior
6. Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats
7. Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin, or accumbens dopamine, but not caffeine
8. NMDA receptors in the nucleus accumbens modulate intravenous cocaine, but not heroin self-administration in the rat
9. Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat
10. Cocaine receptors on dopamine transporters are related to self-administration of cocaine
11. Effects of cocaine and the cocaine analog CFT on glutamatergic neurons
12. Excitant amino acid projections from rat amygdala and thalamus to nucleus accumbens
13. Changes in relative amounts of aspartate and glutamate released and retained in hippocampal slices during depolarization
14. Biochemical evidence for overlapping neocortical and allocortical glutamate projections to the nucleus accumbens and rostral caudatoputamen in the rat brain
15. The effects of surgical and chemical lesions on neurotransmitter candidates in the nucleus accumbens of the rat
16. Blockade of the locomotor stimulant effects of cocaine and methamphetamine by glutamate antagonists
17. Functional interaction of dopamine and glutamate in the nucleus accumbens in the regulation of locomotion
18. Low doses of accumbens dopamine modulate amygdala suppression of spontaneous exploratory activity in rats
19. Distinct actions of endogenous excitatory amino acids on the outflow of dopamine in the nucleus accumbens