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Volumn 172, Issue 1, 1995, Pages 161-172

Oral immunization with recombinant helicobacter pyloriurease induces secretory iga antibodies and protects mice from challenge with helicobacter felis

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL ENZYME; BACTERIAL VACCINE; CHOLERA TOXIN; ESCHERICHIA COLI ENTEROTOXIN; FREUND ADJUVANT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MURAMYL DIPEPTIDE DERIVATIVE; RECOMBINANT PROTEIN; SECRETORY IMMUNOGLOBULIN; UREASE;

EID: 0029069313     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/172.1.161     Document Type: Article
Times cited : (203)

References (70)
  • 1
    • 0001073992 scopus 로고
    • Epidemiology and natural history of helicobacter
    • Blaser MJ, Smith PD, Ravdin J, eds., New York: Raven Press
    • Taylor DN, Parsonnet J. Epidemiology and natural history of Helicobacterpylori infection. In: Blaser MJ, Smith PD, Ravdin J, eds. Infections of the gastrointestinal tract. New York: Raven Press, 1994.
    • (1994) Infections of the Gastrointestinal Tract
    • Taylor, D.N.1    Parsonnet, J.2
  • 2
    • 0025349492 scopus 로고
    • Helicobacter pylori
    • Blaser MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 1990;161:626-33.
    • (1990) J Infect Dis , vol.161 , pp. 626-633
    • Blaser, M.J.1
  • 3
    • 0027285297 scopus 로고
    • Pathogenicity of helicobacter pylori: A perspective
    • Lee A, Fox J, Hazell SL. Pathogenicity of Helicobacter pylori: a perspective. Infect Immun 1993;61:1601-10.
    • (1993) Infect Immun , vol.61 , pp. 1601-1610
    • Lee, A.1    Fox, J.2    Hazell, S.L.3
  • 4
    • 0027026302 scopus 로고
    • Helicobacter pylori
    • Scolnick JV, Tompkins LS. Helicobacter pylori and gastroduodenal disease: pathogenesis and host-parasite interaction. Infect Agents Dis 1993;1:294-309.
    • (1993) Infect Agents Dis , vol.1 , pp. 294-309
    • Scolnick, J.V.1    Tompkins, L.S.2
  • 5
    • 0026643058 scopus 로고
    • Helicobacter pylori
    • Cover TL, Blaser MJ. Helicobacter pylori and gastroduodenal disease. Annu Rev Med 1992;43:135-45.
    • (1992) Annu Rev Med , vol.43 , pp. 135-145
    • Cover, T.L.1    Blaser, M.J.2
  • 6
    • 0004071631 scopus 로고
    • Geographic distribution and association with gastriccancer
    • Northfield TC, Mendall M, Goggin PM, eds., Dordrecht, Germany: Kluwer Academic Publishers
    • Forman D, Webb P. Geographic distribution and association with gastric cancer. In: Northfield TC, Mendall M, Goggin PM, eds.Helicobacter pylori infection. Dordrecht, Germany: Kluwer Academic Publishers, 1993:11-20.
    • (1993) Helicobacter Pylori , pp. 11-20
    • Forman, D.1    Webb, P.2
  • 7
    • 0027213922 scopus 로고
    • Regression of primary low-grade b-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of helicobacter pylori
    • Wotherspoon AC, Doglioni C, Diss TC, et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori.Lancet 1993;2:575-7.
    • (1993) Lancet , vol.2 , pp. 575-577
    • Wotherspoon, A.C.1    Doglioni, C.2    Diss, T.C.3
  • 8
    • 0026808787 scopus 로고
    • Natural history of gastritis and the relationship to peptic ulcerdisease
    • Sipponen P. Natural history of gastritis and the relationship to peptic ulcer disease. Digestion 1990;5:70-5.
    • (1990) Digestion , vol.5 , pp. 70-75
    • Sipponen, P.1
  • 9
    • 0025744847 scopus 로고
    • Oral immunization against helicobacter pylori
    • Czinn SJ, Nedrud JG. Oral immunization against Helicobacter pylori. Infect Immun 1991;59:2359-63.
    • (1991) Infect Immun , vol.59 , pp. 2359-2363
    • Czinn, S.J.1    Nedrud, J.G.2
  • 10
    • 0026536465 scopus 로고
    • Immunization against gastric helicobacterinfection in a mousdhelicobacterfelis model
    • Chen M, Lee A, Hazell SL. Immunization against gastric helicobacter infection in a mousdHelicobacterfelis model. Lancet 1992;339:1120-1.
    • (1992) Lancet , vol.339 , pp. 1
    • Chen, M.1    Lee, A.2    Hazell, S.L.3
  • 11
    • 0011763878 scopus 로고
    • Immunization against gastric infection with
    • Chen M, Lee A, Hazell SL. Immunization against gastric infection with Helicobacter species: first step in the prophylaxis of gastric cancer. Zentralbl Mikrobiol 1993;180:155-65.
    • (1993) Zentralbl Mikrobiol , vol.180 , pp. 155-165
    • Chen, M.1    Lee, A.2    Hazell, S.L.3
  • 12
    • 0027265078 scopus 로고
    • Protection of germ-free mice from infection
    • Czinn SJ, Cai A, Nedrud JCI. Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization. Vaccine 1993;11:637-42.
    • (1993) Vaccine , vol.11 , pp. 637-642
    • Czinn, S.J.1    Cai, A.2    Nedrud, J.3
  • 14
    • 0028068834 scopus 로고
    • Immunization of balb/c mice against helicobacter felis infection with helicobacter pylori urease
    • Michetti P, Corthesy-Theulaz I, Davin C, et al. immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease. Gastroenterology 1994;107:1002-11.
    • (1994) Gastroenterology , vol.107 , pp. 1002-1011
    • Michetti, P.1    Corthesy-Theulaz, I.2    Davin, C.3
  • 15
    • 12644254815 scopus 로고
    • Effect of oralimmunization with helicobacter pylori antigens on colonization by helicobacter felis in mice
    • Thomas WD Jr, Lee CK, Lofsky A, Nichols R, Houle D. Effect of oral immunization with Helicobacter pylori antigens on colonization by Helicobacter felis in mice. Acta Gastroenterol Belg 1993;56:4.
    • (1993) Acta Gastroenterol Belg , vol.56 , pp. 4
    • Thomas, W.D.1    Lee, C.K.2    Lofsky, A.3    Nichols, R.4    Houle, D.5
  • 16
    • 0025979283 scopus 로고
    • Shuttle cloning and nucleotide sequence of helicobacter pylori genes responsible for urease activity
    • Labigne A, Cussac V, Courcoux P. Shuttle cloning and nucleotide sequence of Helicobacter pylori genes responsible for urease activity. J Bacteriol 1991;173:1920-31.
    • (1991) J Bacteriol , vol.173 , pp. 1920-1931
    • Labigne, A.1    Cussac, V.2    Courcoux, P.3
  • 17
    • 0026780250 scopus 로고
    • Purification of recombinant
    • Hu LT, Foxall PA, Russell R, Mobley HLT. Purification of recombinant Helicobacter pylori urease apoenzyme encoded by ureA and ureB.Infect Immun 1992;60:2657-66.
    • (1992) Infect Immun , vol.60 , pp. 2657-2666
    • Hu, L.T.1    Foxall, P.A.2    Russell, R.3    Mobley, H.4
  • 18
    • 0023691364 scopus 로고
    • Isolation of a spiral-shapedbacterium from the cat stomach
    • Lee A, Hazell SL, O’Rourke J, Kouprach S. Isolation of a spiral-shaped bacterium from the cat stomach. Infect Immun 1988;56:2843-50.
    • (1988) Infect Immun , vol.56 , pp. 2843-2850
    • Lee, A.1    Hazell, S.L.2    O’Rourke, J.3    Kouprach, S.4
  • 24
    • 0021877177 scopus 로고
    • Modified steiner method for the demonstration of spirochetes
    • Garvey W, Fathi A, Bigelow F. Modified Steiner method for the demonstration of spirochetes. J Histotechnol 1985;8:15-7.
    • (1985) J Histotechnol , vol.8 , pp. 15-17
    • Garvey, W.1    Fathi, A.2    Bigelow, F.3
  • 25
    • 0028012322 scopus 로고
    • Oral administration of polymeric immunoglobulin a prevents colonization with vibrio cholerae in neonatal mice
    • Lee CK, Weltzin R, Soman G, Georgakopoulos KM, Houle DM, Monath TP. Oral administration of polymeric immunoglobulin A prevents colonization with Vibrio cholerae in neonatal mice. Infect Immun 1994;62:887-91.
    • (1994) Infect Immun , vol.62 , pp. 887-891
    • Lee, C.K.1    Weltzin, R.2    Soman, G.3    Georgakopoulos, K.M.4    Houle, D.M.5    Monath, T.P.6
  • 26
    • 0027203527 scopus 로고
    • Cloning, expression, and sequencing of helicobacter felis urease genes
    • Ferrerò RL, Labigne A. Cloning, expression, and sequencing of Helicobacter felis urease genes. Mol Microbiol 1993;9:323-33.
    • (1993) Mol Microbiol , vol.9 , pp. 323-333
    • Ferrerò, R.L.1    Labigne, A.2
  • 27
    • 0026074892 scopus 로고
    • Macromolecular structure and
    • Austin JW, Doig P, Stewart M, Trust T. Macromolecular structure and aggregation states of Helicobacter pylori urease. J Bacteriol 1991; 173:5663-7.
    • (1991) J Bacteriol , vol.173 , pp. 5663-5667
    • Austin, J.W.1    Doig, P.2    Stewart, M.3    Trust, T.4
  • 28
    • 0028284154 scopus 로고
    • Pre-formed urease activity of helicobacter pylori as determined by a viable cell count technique—clinical implications
    • Xia HX, Keane CT, Omorain CA. Pre-formed urease activity of Helicobacter pylori as determined by a viable cell count technique—clinical implications. J Med Microbiol 1994;40:435-9.
    • (1994) J Med Microbiol , vol.40 , pp. 435-439
    • Xia, H.X.1    Keane, C.T.2    Omorain, C.A.3
  • 29
    • 0025281747 scopus 로고
    • Vaccination against helicobacter pylori urease
    • Pallen MJ, Clayton CL. Vaccination against Helicobacter pylori urease. Lancet 1990;2:186-7.
    • (1990) Lancet , vol.2 , pp. 186-187
    • Pallen, M.J.1    Clayton, C.L.2
  • 30
    • 0025247997 scopus 로고
    • Purification and n-terminal analysis of urease from
    • Hu LT, Mobley HLT. Purification and N-terminal analysis of urease from Helicobacter pylori.Infect Immun 1990;58:992-8.
    • (1990) Infect Immun , vol.58 , pp. 992-998
    • Hu, L.T.1    Mobley, H.2
  • 31
    • 0025002223 scopus 로고
    • Investigation of the structure andlocalization of the urease of helicobacter pylori using monoclonal antibodies
    • Hawtin PR, Stacey AR, Newell DG. Investigation of the structure and localization of the urease of Helicobacter pylori using monoclonal antibodies. J Gen Microbiol 1990;136:1995-2000.
    • (1990) J Gen Microbiol , vol.136 , pp. 1995-2000
    • Hawtin, P.R.1    Stacey, A.R.2    Newell, D.G.3
  • 32
    • 0028122564 scopus 로고
    • Effect of gastric ph on urease-dependent colonization of gnotobiotic piglets by helicobacter pylori
    • Eaton KA, Krakowka S. Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori.Infect Immun 1994;62:3604-7.
    • (1994) Infect Immun , vol.62 , pp. 3604-3607
    • Eaton, K.A.1    Krakowka, S.2
  • 33
    • 0028064605 scopus 로고
    • A urease-negative mutant of helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach
    • Tsuda M, Karita M, Morshed MG, Okita K, Nakazawa T. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach. Infect Immun 1994;62:3586-9.
    • (1994) Infect Immun , vol.62 , pp. 3586-3589
    • Tsuda, M.1    Karita, M.2    Morshed, M.G.3    Okita, K.4    Nakazawa, T.5
  • 34
    • 0000522135 scopus 로고
    • The importance of urease in acid protection for thegastric-colonizing bacteria helicobacter pylori and h. Felis sp nov
    • Ferrerò RL, Lee A. The importance of urease in acid protection for the gastric-colonizing bacteria Helicobacter pylori and H. felis sp nov. Microbiol Ecol Health Dis 1991;4:121-34.
    • (1991) Microbiol Ecol Health Dis , vol.4 , pp. 121-134
    • Ferrerò, R.L.1    Lee, A.2
  • 35
    • 0027203527 scopus 로고
    • Cloning, expression, and sequencing of helicobacter felis urease genes
    • Ferrerò RL, Labigne A. Cloning, expression, and sequencing of Helicobacter felis urease genes. Mol Microbiol 1993;9:323-33.
    • (1993) Mol Microbiol , vol.9 , pp. 323-333
    • Ferrerò, R.L.1    Labigne, A.2
  • 37
    • 0025151949 scopus 로고
    • A small animal model of human
    • Lee A, Fox JG, Otto G, Murphy J. A small animal model of human Helicobacter pylori active chronic gastritis. Gastroenterology 1990; 99:1315-23.
    • (1990) Gastroenterology , vol.99 , pp. 1315-1323
    • Lee, A.1    Fox, J.G.2    Otto, G.3    Murphy, J.4
  • 39
    • 0025069886 scopus 로고
    • Controlled vaccine release in the gut-associated lymphoid tissues.I. Orally administered biodegradable microspheres target the peyer’s patches
    • Eldridge JH, Hammond CJ, Meulbrook JA, Staas JK, Gilley RM, Tice TR. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer’s patches. J Controlled Release 1990;11:205-14.
    • (1990) J Controlled Release , vol.11 , pp. 205-214
    • Eldridge, J.H.1    Hammond, C.J.2    Meulbrook, J.A.3    Staas, J.K.4    Gilley, R.M.5    Tice, T.R.6
  • 40
    • 0028798530 scopus 로고
    • Uptake andtransport of copolymer biodegradable microspheres by rabbit peyer’s patch m cells
    • Ermak TH, Dougherty EP, Bhagat HR, Kabok Z, Pappo J. Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer’s patch M cells. Cell Tissue Res 1995;279:433-6.
    • (1995) Cell Tissue Res , vol.279 , pp. 433-436
    • Ermak, T.H.1    Dougherty, E.P.2    Bhagat, H.R.3    Kabok, Z.4    Pappo, J.5
  • 41
    • 3142569500 scopus 로고
    • Physicochemical characterization of nanoparticles and their potential for vaccine preparation
    • Kreuter J. Physicochemical characterization of nanoparticles and their potential for vaccine preparation. Vaccine Res 1992;1:93-8.
    • (1992) Vaccine Res , vol.1 , pp. 93-98
    • Kreuter, J.1
  • 43
    • 0023945299 scopus 로고
    • Resident salivary gland macrophagesfunction as accessory cells in antigen-dependent t-cell proliferation
    • Pappo J, Ebersole JL, Taubman MA. Resident salivary gland macrophages function as accessory cells in antigen-dependent T-cell proliferation. Immunology 1988;63:99-104.
    • (1988) Immunology , vol.63 , pp. 99-104
    • Pappo, J.1    Ebersole, J.L.2    Taubman, M.A.3
  • 44
    • 0343687075 scopus 로고
    • Northfield, Dordrecht, Netherlands: Kluwer Academic Publishers
    • Chen M, Lee A. Vaccination possibilities and probabilities, in: Northfield TC, Mendall M, Goggin PM, eds. Helicobacter pylori infection. Dordrecht, Netherlands: Kluwer Academic Publishers, 1993:158-67.
    • (1993) Vaccination Possibilities and Probabilities , pp. 158-167
    • Chen, M.1    Lee, A.2
  • 45
    • 0026663079 scopus 로고
    • Chronic active gastritis due to helicobacter pylori
    • Eaton KA, Krakowka S. Chronic active gastritis due to Helicobacter pyloriin immunized gnotobiotic piglet. Gastroenterology 1992;103:1580-6.
    • (1992) Gastroenterology , vol.103 , pp. 1580-1586
    • Eaton, K.A.1    Krakowka, S.2
  • 46
    • 0022504962 scopus 로고
    • Systemic and local antibody responses to gastric campylobacterpyloridis in non-ulcer dyspepsia
    • Rathbone BJ, Wyatt JI, Worsley BW. Systemic and local antibody responses to gastric Campylobacterpyloridis in non-ulcer dyspepsia. Gut 1986;27:642-7.
    • (1986) Gut , vol.27 , pp. 642-647
    • Rathbone, B.J.1    Wyatt, J.I.2    Worsley, B.W.3
  • 47
    • 84959847308 scopus 로고
    • Northfield TC, Mendall M, Goggin, Dordrecht, Netherlands: Kluwer Academic Publishers
    • Crabtree J, Wyatt J. Host responses. In: Northfield TC, Mendall M, Goggin PM, eds. Helicobacter pylori infection. Dordrecht, Netherlands: Kluwer Academic Publishers, 1993:40-52.
    • (1993) Host responses , pp. 40-52
    • Crabtree, J.1    Wyatt, J.2
  • 48
    • 0025772922 scopus 로고
    • Mucosal humoral immune
    • Crabtree JE, Shallcross TM, Wyatt Ji, et al. Mucosal humoral immune response to Helicobacter pylori in patients with duodenitis. Dig Dis Sei 1991;36:1266-73.
    • (1991) Dig Dis Sei , vol.36 , pp. 1266-1273
    • Crabtree, J.E.1    Shallcross, T.M.2    Ji, W.3
  • 49
    • 84959806406 scopus 로고
    • Immunology of helicobacter pylori
    • Marshall BJ, et al., eds, Oxford, UK: Blackwell Scientific Publications
    • Kist M. Immunology of Helicobacter pylori. In: Marshall BJ, et al., eds. Helicobacter pylori in peptic ulceration and gastritis. Oxford, UK: Blackwell Scientific Publications, 1991:92 110.
    • (1991) Helicobacter Pylori , vol.92 , pp. 110
    • Kist, M.1
  • 50
    • 0027298994 scopus 로고
    • Local and systemic immune responses in murine helicobacter felis active chronic gastritis
    • Fox JG, Blanco M, Murphy JC, et al. Local and systemic immune responses in murine Helicobacter felis active chronic gastritis. Infect Immun 1993;61:2309-15.
    • (1993) Infect Immun , vol.61 , pp. 2309-2315
    • Fox, J.G.1    Blanco, M.2    Murphy, J.C.3
  • 51
    • 0021326041 scopus 로고
    • Specific and non-specifichumoral defense factors in the epithelium of normal and inflamed gastric mucosa
    • Valnes K, Braentzaeg P, Elgjo K, Stave R. Specific and non-specific humoral defense factors in the epithelium of normal and inflamed gastric mucosa. Gastroenterology 1984;86:402-12.
    • (1984) Gastroenterology , vol.86 , pp. 402-412
    • Valnes, K.1    Braentzaeg, P.2    Elgjo, K.3    Stave, R.4
  • 52
    • 0026503127 scopus 로고
    • Assay ofurease-inhibiting activity in serum from children infected with helicobacter pylori
    • Thomas JE, Whatmore AM, Kehow MA, Skillen AW, Barer M. Assay of urease-inhibiting activity in serum from children infected with Helicobacter pylori.J Clin Microbiol 1992;30:1338-40.
    • (1992) J Clin Microbiol , vol.30 , pp. 1338-1340
    • Thomas, J.E.1    Whatmore, A.M.2    Kehow, M.A.3    Skillen, A.W.4    Barer, M.5
  • 53
    • 0019363173 scopus 로고
    • Host defense mechanisms at mucosal surfaces
    • McNabb PC, Tomasi TB. Host defense mechanisms at mucosal surfaces. Annu Rev Microbiol 1981;35:477-96.
    • (1981) Annu Rev Microbiol , vol.35 , pp. 477-496
    • McNabb, P.C.1    Tomasi, T.B.2
  • 55
    • 0023236932 scopus 로고
    • Intestinal mucus gel and secretoryantibody are barriers to campylobacter jejuni adherence to tnt 407 cells
    • McSweegan E, Burr DH, Walker RI. Intestinal mucus gel and secretory antibody are barriers to Campylobacter jejuni adherence to TNT 407 cells. Infect Immun 1987;55:1431-5.
    • (1987) Infect Immun , vol.55 , pp. 1431-1435
    • McSweegan, E.1    Burr, D.H.2    Walker, R.I.3
  • 57
    • 0026772605 scopus 로고
    • Monoclonalsecretory immunoglobulin a protects mice against oral challenge with the invasive pathogen salmonella typhimurium
    • Michetti P, Mahan MJ, Slauch JM, Mekalanos JJ, Neutra MR. Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium.Infect Immun 1992;60:1786-92.
    • (1992) Infect Immun , vol.60 , pp. 1786-1792
    • Michetti, P.1    Mahan, M.J.2    Slauch, J.M.3    Mekalanos, J.J.4    Neutra, M.R.5
  • 58
    • 0000956522 scopus 로고
    • Studies on the mechanism of action of intestinal antibody inexperimental cholera
    • Freier R. Studies on the mechanism of action of intestinal antibody in experimental cholera. Tex Rep Biol Med 1969;27:299-316.
    • (1969) Tex Rep Biol Med , vol.27 , pp. 299-316
    • Freier, R.1
  • 59
    • 0018348986 scopus 로고
    • Intestinal goblet cell mucus release.Ii. In vivo stimulation by antigen in the immunized rat
    • Lake AM, Block KJ, Neutra MR. Intestinal goblet cell mucus release. II. In vivo stimulation by antigen in the immunized rat. J Immunol 1979;122:834-7.
    • (1979) J Immunol , vol.122 , pp. 834-837
    • Lake, A.M.1    Block, K.J.2    Neutra, M.R.3
  • 60
    • 0024503744 scopus 로고
    • Antigens for the serodiagnosis of campylobacter
    • Newell DG, Stacy A. Antigens for the serodiagnosis of Campylobacterpylori infections. Gastroenterol Clin Biol 1989; 13:37B-41B.
    • (1989) Gastroenterol Clin Biol , vol.13
    • Newell, D.G.1    Stacy, A.2
  • 61
    • 0025369322 scopus 로고
    • Purification and characterization of urease from helicobacter pylori
    • Dunn BE, Campbell GP, Perez-Perez G, Blaser MJ. Purification and characterization of urease from Helicobacter pylori.J Biol Chem 1990; 265:9464-9.
    • (1990) J Biol Chem , vol.265 , pp. 9464-9469
    • Dunn, B.E.1    Campbell, G.P.2    Perez-Perez, G.3    Blaser, M.J.4
  • 63
    • 0028220582 scopus 로고
    • Shimoharam, et al. Synergistic action of choleratoxin b subunit (and escherichia coli heat-labile toxin b subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine
    • Tamura SI, Yamanaka A, ShimoharaM, et al. Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine. Vaccine 1994;12:419-25.
    • (1994) Vaccine , vol.12 , pp. 419-425
    • Tamura, S.I.1    Yamanaka, A.2
  • 64
    • 0025319074 scopus 로고
    • Whole cholera toxin and b subunitact synergistically as an adjuvant for the mucosal immune response of mice to keyhole limpet haemocyanin
    • Wilson AD, Clarke CJ, Stokes CR. Whole cholera toxin and B subunit act synergistically as an adjuvant for the mucosal immune response of mice to keyhole limpet haemocyanin. Scand J Immunol 1990; 31:443 51.
    • (1990) Scand J Immunol , vol.443 , Issue.51 , pp. 31
    • Wilson, A.D.1    Clarke, C.J.2    Stokes, C.R.3
  • 65
    • 0027963450 scopus 로고
    • Successful immunization against gastric infection with
    • Lee A, Chen M. Successful immunization against gastric infection with Helicobacter species: use of a cholera toxin B-subunit whole cell vaccine. Infect Immun 1994;62:3594-7.
    • (1994) Infect Immun , vol.62 , pp. 3594-3597
    • Lee, A.1    Chen, M.2
  • 66
    • 0023938398 scopus 로고
    • Adjuvant activity of escherichia
    • Clements JD, Hartzog NM, Lyons FL. Adjuvant activity of Escherichiacoli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine 1988;6:269 77.
    • (1988) Vaccine , vol.269 , Issue.77 , pp. 6
    • Clements, J.D.1    Hartzog, N.M.2    Lyons, F.L.3
  • 67
    • 0027298150 scopus 로고
    • Use of heat-labile toxin of escherichia coli tofacilitate mucosal immunization
    • Walker RI, Clements JD. Use of heat-labile toxin of Escherichia coli to facilitate mucosal immunization. Vaccine Res 1993;2:1-10.
    • (1993) Vaccine Res , vol.2 , pp. 1-10
    • Walker, R.I.1    Clements, J.D.2
  • 68
    • 0002013261 scopus 로고
    • The structure and immunomodulating functionof glucosaminylmuramyl peptides
    • Andronova T, Ivanov V. The structure and immunomodulating function of glucosaminylmuramyl peptides. Soviet Med Rev D: Immunol 1991;4:1-63.
    • (1991) Soviet Med Rev D: Immunol , vol.4 , pp. 1-63
    • Andronova, T.1    Ivanov, V.2
  • 69
    • 0028933462 scopus 로고
    • Effectof oral immunization with recombinant urease on murine helicobacter felis gastritis
    • Pappo J, Thomas WD Jr, Kabok Z, Taylor NS, Murphy JC, Fox JG. Effect of oral immunization with recombinant urease on murine Helicobacter felis gastritis. Infect Immun 1995;63:1246-52.
    • (1995) Infect Immun , vol.63 , pp. 1246-1252
    • Pappo, J.1    Thomas, W.D.2    Kabok, Z.3    Taylor, N.S.4    Murphy, J.C.5    Fox, J.G.6
  • 70
    • 0026570302 scopus 로고
    • Surface proteins from helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa
    • Mai UE, Perez-Pcrez GI, Allen JB, Wahl SM, Blaser MJ, Smith PD. Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa. J Exp Med 1992; 175:517 25.
    • (1992) J Exp Med , vol.517 , Issue.25 , pp. 175
    • Mai, U.E.1    Perez-Pcrez, G.I.2    Allen, J.B.3    Wahl, S.M.4    Blaser, M.J.5    Smith, P.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.