Adjuvant Recombinant Human Growth Hormone Normalizes Plasma Amino Acids in Parenterally Fed Trauma Patients

Journal of Parenteral and Enteral Nutrition

Volumn 19, Issue 2, 1995, Pages 137-144

  Jeevanandam, Malayappa ^a   Ali, Mohammed R ^a   Holaday, Nancy J ^a   Petersen, Scott R ^a  

^a ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE;

ADULT; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ARTICLE; CLINICAL ARTICLE; DIET THERAPY; FEMALE; HORMONAL REGULATION; HUMAN; HYPERMETABOLISM; INJURY; MALE; MUSCLE MASS; NITROGEN METABOLISM; NUTRITIONAL SUPPORT; PARENTERAL NUTRITION; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ADULT; AMINO ACIDS; BLOOD UREA NITROGEN; CHEMOTHERAPY, ADJUVANT; FEMALE; GROWTH HORMONE; HUMAN; INJECTIONS, INTRAMUSCULAR; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGE; MULTIPLE TRAUMA; NITROGEN; PARENTERAL NUTRITION, TOTAL; RECOMBINANT PROTEINS;

EID: 0029069275     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1177/0148607195019002137     Document Type: Article

References (32)

1. Askanazi J., Carpentier YA, Michelson CB, et al: Muscle and plasma amino acids following injury: influence of intercurrent infection. Ann Surg 192:78-85, 1980.
2. Jeevanandam M., Young DH, Ramias L., et al: Aminoaciduria of severe trauma. Am J Clin Nutr 49:814-822, 1989.
3. Wannemacher RW Jr, Redarek RS, Bartelloni PJ, et al: Changes in individual plasma amino acids following experimentally induced sand fly fever virus infection. Metabolism 21:67-72, 1972.
4. Legaspi A.: Adjunctive therapy for nutritional support in hospitalized patients. NCP 4:95-100, 1989.
5. Lundeberg S., Belfrage M., Wernerman J., et al: Growth hormone improves muscle protein metabolism and whole-body nitrogen economy in man during a hyponitrogenous diet. Metabolism 40:315-322, 1991.
6. Petersen SR, Holaday NJ, Jeevanandam M.: Enhancement of protein synthesis efficiency (PSE) in parenterally fed trauma patients by adjuvant recombinant human growth hormone (rgGH). J Trauma 36:726-733, 1994.
7. Ziegler T., Young LS, Ferrari-Baliviera E., et al: Use of human growth hormone combined with nutritional support in a critical care unit. JPEN 14:574-581, 1990.
8. Ponting GA, Ward HC, Halliday D., et al: Protein and energy metabolism with biosynthetic human growth hormone in patients on full intravenous nutritional support. JPEN 14:437-441, 1990.
9. Mjaaland M., Unneberg K., Larsson J., et al: Growth hormone after abdominal surgery attenuates forearm glutamine, alanine, 3-methyl-histidine, and total amino acid flux in patients receiving total parenteral nutrition. Ann Surg 217:413-422, 1993.
10. Jeevanandam M., Ramias L., Shamos RF, et al: Decreased growth hormone levels in the catabolic phase of severe injury. Surgery 111:495-502, 1992.
11. Salomon F., Cuneo R., Sonksen PH: Growth hormone and protein metabolism. Horm Res 36:41-43, 1991.
12. Jeevanandam M., Young DH, Ramias L., et al: Effect of major trauma on plasma free amino acid concentrations in geriatric patients. Am J Clin Nutr 51:1040-1045, 1990.
13. Bergstrom J., Furst P., Vinnars E.: Effect of a test meal, without and with protein, on muscle and plasma free amino aicds. Clin Sci 79:331-337, 1990.
14. Young VR, Bier DM, Pellett PL: A theoretical basis for increasing current estimates of the amino acid requirements in adult man with experimental support. Am J Clin Nutr 50:80-92, 1989.
15. Jeevanandam M., Holaday NJ, Shamos RF, et al: Acute IGF-1 deficiency in multiple trauma victims. Clin Nutr 11:352-357, 1992.
16. Palekar AG, Collip PJ, Maddaiah VT: Growth hormone and rat liver mitochondria effects on urea cycle enzymes. Biochem Biophy Res Commun 100:1604-1610, 1981.
17. Morris SM Jr: Regulation of enzymes of urea and arginine synthesis. Annu Rev Nutr 12:81-101, 1992.
18. Wannemacher RW Jr: Key role of various amino acids in host response to infection. Am J Clin Nutr 30:1269-1280, 1977.
19. Long CL, Kinney JM, Geiger JW: Nonsuppressability of gluconeogenesis by glucose in septic patients. Metabolism 25:193-201, 1976.
20. Shaw JHF, Klein S., Wolfe RR: Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. Surgery 97:557-567, 1985.
21. Moller N., Jorgensens JOL, Schmitz O., et al: Effects of a growth hormone pulse on total and forearm substrate fluxes in humans. Am J Physiol 258: E86-E91, 1990.
22. Gore DC, Honeycutt D., Jahoor F., et al. Effect of exogenous growth hormone on glucose utilization in burn patients. J Surg Res 51:518-523, 1991.
23. Wellbourne T.: Role of glucocorticoids in regulating interorgan glutamine flow during chronic metabolic acidosis. Metabolism 37:520-525, 1988.
24. Pacitti AJ, Inoue Y., Plumley DA, et al: Growth hormone regulates amino acid transport in human and rat liver. Ann Surg 216:353-362, 1992.
25. Wellbourne T., Joshi S., McVie R.: Growth hormone effects on hepatic glutamate handling in vivo. Am J Physiol 257: E59-E62, 1989.
26. Hammerqvist F., Stromberg C., von der Decken A., et al: Biosynthetic human growth hormone preserves both muscle protein synthesis and the decrease in muscle-free glutamine and improves whole-body nitrogen economy after operation. Ann Surg 216:184-191, 1992.
27. Jiang Z-M., He G-Z., Zhang S-Y., et al: Low dose growth hormone and hypocaloric nutrition attenuate the protein-catabolic response after major operation. Ann Surg 210:513-525, 1989.
28. Fryburg DA, Gelfano RA, Barrett EJ: Growth hormone acutely stimulates forearm protein synthesis in normal humans. Am J Physiol 200: E499-E504, 1991.
29. Froesch ER, Schmid C., Schwander J., et al: Actions of insulin-like growth factors. Ann Re Physiol 47:443-467, 1985.
30. Mathews LS, Hammer RE, Brinster RL, et al: Expression of insulin-like growth factor 1 in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology 123:433-438, 1988.
31. Kimbough TD, Sherman S., Ziegler TR, et al: Insulin-like growth factor-1 response is comparable following intravenous and subcutaneous administration of growth hormone. J Surg Res 51:472-476, 1991.
32. Boulware SD, Tamborlane WV, Matthews LS, et al: Diverse effects of insulin-like growth factor 1 on glucose, lipid and amino acid metabolism. Am J Physiol 262: E130-E133, 1992.