+ T cells in mouse strains of different MHC haplotypes, pointing to a non-polymorphic MHC ligand as the positively selecting element. The mouse TCR α-chain is homologous to an invariant TCR α-chain utilized by a subset of human peripheral blood lymphocytes, establishing the existence of a similar MHC ligand and T-cell differentiation pathway in humans.
The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms
Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor
A proline in position 162 in the α2 helix of the MHC I like FcRη closes the peptide-binding groove. The same proline is conserved in all known CD1 molecules.
The Mycobacterium tuberculosis antigen recognized by a human αβ T cell clone in association with CD1b is characterized as being a lipid, mycolic acid. This extraordinary observation may suggest that human CD1b, and perhaps also the other members of the CD1 family, have evolved to present lipid antigens to T cells.