Glycosylated Peptide Hormones: Pharmacological Properties and Conformational Studies of Analogues of [1-Desamino,8-D-arginine]vasopressin

Journal of Medicinal Chemistry

Volumn 38, Issue 1, 1995, Pages 161-169

  Kihlberg, Jan ^a   Åhman, Jens ^a   Walse, Björn ^a   Drakenberg, Torbjörn ^a   Nilsson, Anders ^b   Söderberg Ahlm, Christina ^b   Bengtsson, Bengt ^b   Olsson, Håkan ^b  

^a LUND INSTITUTE OF TECHNOLOGY   (Sweden)

^b Ferring AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

9 FLUORENYLMETHYL CHLOROFORMATE; CHYMOTRYPSIN A; DESMOPRESSIN; GLYCOSYLATED PROTEIN; HORMONE ANALOG; HUMAN SERUM ALBUMIN; MACROGOL 4000; PEPTIDE HORMONE; THIOBUTABARBITAL; VASOPRESSIN ANTAGONIST; VASOPRESSIN DERIVATIVE; VASOPRESSIN V2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIURESIS; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG HALF LIFE; GLYCOSYLATION; HORMONE RECEPTOR INTERACTION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PEPTIDE SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SMALL INTESTINE ABSORPTION;

AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL AVAILABILITY; CHYMOTRYPSIN; COMPARATIVE STUDY; DESMOPRESSIN; DRUG STABILITY; GLYCOPROTEINS; GLYCOSYLATION; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; VASOPRESSINS;

EID: 0029063811     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00001a021     Document Type: Article

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