The Influence of the p-Alkyl Substituent on the Isomerization of o-Quinones to p-Quinone Methides: Potential Bioactivation Mechanism for Catechols

Chemical Research in Toxicology

Volumn 8, Issue 4, 1995, Pages 537-544

  Iverson, Suzanne L ^a   Bolton, Judy L ^a   Hu, Li Qing ^b   Vukomanovic, Vesna ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL; CYTOCHROME P450; QUINOLONE DERIVATIVE;

ALKYLATION; ARTICLE; CELL DAMAGE; ISOMERISM; STRUCTURE ACTIVITY RELATION; TOXICOLOGY;

ALKYLATION; ANIMAL; BIOTRANSFORMATION; CATECHOLS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; GLUTATHIONE; HYDROLYSIS; IN VITRO; ISOMERISM; KINETICS; MALE; MICROSOMES, LIVER; OXIDATION-REDUCTION; QUINONES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029061720     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx00046a007     Document Type: Article

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