Prepubertal testosterone treatment of female rats: Defeminization of behavioral and endocrine function in adulthood

Neuroscience and Biobehavioral Reviews

Volumn 19, Issue 2, 1995, Pages 177-186

  Bloch, G J ^a   Mills, R ^a   Gale, S ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Defeminization; FSH; LH; Lordois; Prepubertal steroids; Proceptive behavior; Sexual differentiation; Testosterone

Indexed keywords

ANDROGEN; ESTRADIOL BENZOATE; ESTROGEN; FOLLITROPIN; GONADOTROPIN; LUTEINIZING HORMONE; PROGESTERONE; TESTOSTERONE;

ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; ENDOCRINE FUNCTION; ESTRUS; FEMALE; HORMONE BLOOD LEVEL; LORDOSIS; LUTEINIZING HORMONE RELEASE; NEWBORN; NONHUMAN; OVARY; PENIS; PREPUBERTY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SEX DIFFERENTIATION; SEXUAL BEHAVIOR; VAGINA;

AGING; ANIMAL; BEHAVIOR, ANIMAL; ENDOCRINE GLANDS; ESTRADIOL; ESTRUS; FEMALE; ORGAN WEIGHT; OVARY; POSTURE; PROGESTERONE; RATS; SEX BEHAVIOR, ANIMAL; SEX MATURATION; SUPPORT, U.S. GOV'T, P.H.S.; TESTOSTERONE;

EID: 0029061586     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/0149-7634(95)00065-M     Document Type: Article

References (68)

1. A possible process of the secondary sterilization: Delayed anovulatory syndrome
2. Organizational and activational effects of sex steroids on brain and behavior:a reanalysis
3. Production of anovulatory sterile rats by single injections of testosterone propionate
4. Sex differentiation of cyclic gonadotropin secretion
5. Evidence that the hypothalamus is responsible for androgen-induced sterility in the female rat
6. Variation in the responsiveness of female rats to ovarian hormones as a function of preceding hormonal deprivation
7. Cholecystokinin stimulates and inhibits lordosis behavior in female rats
8. Microinjection of galanin into the medial preoptic nucleus facilitates copulatory behavior in the male rat
9. Prepubertal testosterone treatment of neonatally gonadectomized made rats: Defeminization and masculinization of behavioral and endocrine function in adulthood
10. Effects of a single injection of estradiol valerate on the hypothalamic arcuate nucleus and on reproductive function in the female rat
11. Galanin (GAL) microinjected into the medial preoptic area (MPOA) facilitates copulatory behavior in the male
12. Induction and facilitation of female mating behavior in rats treated neonatally with low doses of testosterone propionate
13. Androgen and development of progesterone responsiveness in male and female rats
14. Progestin receptor induction and sexual behavior by estradiol treatment in male and female rats
15. Progesterone and heterotypical sexual behavior in male rats
16. Changes with age in levels of serum gonadotropins, prolactin, and gonadal steroids in prepubertal male and female rats
17. Microinjection of cholecystokinin into the medial preoptic nucleus facilitates lordosis behavior in the female rat
18. Postneonatal androgenization and adult aggresssive behavior in female mice
19. Hormonal control of receptivity, proceptivity, and sexual motivation
20. Dose-response and time-response relationships between progesterone and the display of patterns of receptive and proceptive behavior in the female rat
21. Chronic free testosterone (T) in female and defeminized male rats during 15–30 days of age: Masculinization of positive feedback regulation of FSH and LH
22. Chronic testosterone (T) in feminized male rats during 15–30 days of age: Sex reversal of behavioral function in adulthood
23. Chronic free testosterone (T) in female rats during 15–30 days of age: Masculinization of ovarian and behavioral function in adulthood
24. The effect of experience and hormones on the initial receptivity in female and male rats
25. Effect of ovarian secretions on female behavioral potentiality in the rat
26. Effects of prenatal exogenous androgen on the sexual behavior of the female albino rat
27. The site of the positive feedback action of estradiol in the rat
28. Influence of age on the response to paranatal administration of a low dose of androgen
29. Gonadal hormones and the perinatal development of neuroendocrine function
30. The neuroendocrinology of reproduction: An overview
31. Effects of low doses of androgen on the differentiation of hypothalamic regulatory control of ovulation in the rat
32. The induction of heterotypical sexual behavior in the rat
33. Neonatal testosterone modifies LH secretion in the adult female rat by altering the opioid-noradrenergic interaction in the medial preoptic area
34. Differential effects of the perinatal steroid environment on three sexually dimorphic parameters of the rat brain
35. Steroid regulation of luteinizing hormone secretion in normal and androgenized rats at different ages
36. Effects of postpubertal ovarian steroids on reproductive function and sexual differentiation of lightly androgenized rats
37. Influence of continued injections of sex steroids on the estrous cycle in the adult rat
38. Formation of corpora lutea in ovarian grafts in ovariectomized adult rats subjected to early postnatal treatment with androgen
39. Galanin (GAL) microinjected into the medial preoptic area (MPOA) facilitates male-typical copulatory behavior in the female
40. Neonatal intrahypothalamic androgen administration:the influence of dose and age on androgenization of female rats
41. Sexual differentiation of the central nervous system
42. Prepubertal testosterone (T) defeminizes or masculinizes medial preoptic area (MPOA) structures in the rat
43. Serum 5-androstane-3,17-diol, androsterone, and testosterone concentrations in the male rat. Influence of age and gonadotropin stimulation
44. Hormonal determinants during infancy of adult sexual behavior in the female rat
45. Differentiation of the capacity for male sexual behavior in the rat
46. Prepubertal treatment with estrogen or testosterone precipitates the loss of regular estrous cyclicity and normal gonadotropin secretion in adult female rats
47. The effects of long-term estrogen exposure on the induction of sexual behavior and measurements of brain estrogen and progestin receptors in the female rat
48. Organizational effects of testosterone via aromatization on feminine reproductive behavior and neural progestin receptors in rat brain
49. Neonatal androgen effects on sexual and nonsexual behavior of adult rats tested under various hormone regimes
50. Comparison of the regulation of luteinizing hormone (LH) secretion in immature and adult rats
51. Androgen concentrations in plasma and testis of developing rats
52. Sexual behavion:normal male patterning in androgenized female rats
53. Independence of temporal patterning of male mating behavior from the influence of androgen during the neonatal period
54. Hormone administration: Peripheral and intracranial implants
55. Changes in sensitivity of the estradiol-LH feedback system with puberty in the female rat
56. The “early androgen” syndrome: Differences in response to prenatal and postnatal administration of various doses of testosterone propionate in female and male rats
57. The effects of estrogen and progesterone on female rat proceptive behavior
58. Effect of a single dose of testosterone propionate on vaginal opening in the rat
59. Changing pro-oestrous surges of luteinizing hormone in ageing 5-day cyclic rats
60. Consequences of perinatal hormone manipulation on the adult sexual behavior of female rats
61. Neonatal castration of male and female rats affects luteinizing hormone responses to estrogen during adulthood
62. Estrogen-progesterone induction of mating in female rats
63. Hormonal determinants of the development of masculine and feminine behavior in male and female rats
64. Influence of age and presence of the ovaries on reproductive function in rats injected with androgens
65. Estradiol-induced daily luteinizing hormone and prolactin surges in young and middle-aged rats: Correlations with age-related changes in pituitary responsiveness and catecholamine turnover rates in microdissected brain areas
66. Age-related changes in cytoplasmic estrogen receptor concentrations in microdissected brain nuclei: Correlations with changes in steroid-induced sexual behavior
67. Nuclear estradiol and cytosol progestin receptor concentrations in the brain and pituitary gland and sexual behavior in ovariectomized estradiol-treated middle-aged rats