-
1
-
-
2442588391
-
-
Levy, J.A, Plenum Press, New York
-
Temin, H.M, in The Retroviridae (ed. Levy, J.A.) 1-18 (Plenum Press, New York; 1992).
-
(1992)
The Retroviridae
, pp. 1-18
-
-
Temin, H.M.1
-
2
-
-
0023852121
-
The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis
-
Fauci, A S. The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 239, 617-622 (1988).
-
(1988)
Science
, vol.239
, pp. 617-622
-
-
Fauci, A.S.1
-
3
-
-
0025298840
-
Structure of the aspartic proteinase from Rous Sarcoma retrovirus refined at 2-A resolution
-
Jask6lski, M., Miller, M., Rao, J.K.M., Leis, J. and Wlodawer, A. Structure of the aspartic proteinase from Rous Sarcoma retrovirus refined at 2-A resolution. Biochem. 29, 5889-5898 (1990).
-
(1990)
Biochem
, vol.29
, pp. 5889-5898
-
-
Jasklski, M.1
Miller, M.2
Rao, J.K.M.3
Leis, J.4
Wlodawer, A.5
-
4
-
-
0024412506
-
Conserved folding in retroviral proteinases: Crystal structure of a synthetic HIV-1 proteinase
-
Wlodawer, A. et al. Conserved folding in retroviral proteinases: Crystal structure of a synthetic HIV-1 proteinase. Science 245, 616-621 (1989).
-
(1989)
Science
, vol.245
, pp. 616-621
-
-
Wlodawer, A.1
-
5
-
-
0024344021
-
Structure of complex of synthetic HIV-1 proteinase with a substrate-based inhibitor at 2.3 A resolution
-
Miller, M. et al. Structure of complex of synthetic HIV-1 proteinase with a substrate-based inhibitor at 2.3 A resolution. Science 246,1149-1152 (1989).
-
(1989)
Science
, vol.246
, pp. 1149-1152
-
-
Miller, M.1
-
6
-
-
0027218692
-
Structure-based inhibitors of HIV-1 proteinase
-
Wlodawer, A. and Erickson, J.W. Structure-based inhibitors of HIV-1 proteinase. A. Rev. Biochem. 62, 543-585 (1993).
-
(1993)
A. Rev. Biochem
, vol.62
, pp. 543-585
-
-
Wlodawer, A.1
Erickson, J.W.2
-
7
-
-
16044375105
-
Crystal structures of HIV-1 proteinase-inhibitor complexes
-
Appelt, K. Crystal structures of HIV-1 proteinase-inhibitor complexes. Persp. in drug Discov. Design 1, 23-48 (1993).
-
(1993)
Persp. in Drug Discov. Design
, vol.1
, pp. 23-48
-
-
Appelt, K.1
-
8
-
-
0027370067
-
The crystallographic structure of the proteinase from human immunodeficiency virus type 2 with two synthetic peptidic transition state analog inhibitors
-
Mulichak, A.M. et al. The crystallographic structure of the proteinase from human immunodeficiency virus type 2 with two synthetic peptidic transition state analog inhibitors. J biol. Chem. 268, 13103-13109 (1993).
-
(1993)
J Biol. Chem
, vol.268
, pp. 13103-13109
-
-
Mulichak, A.M.1
-
9
-
-
0027321544
-
Crystal structure of human immunodeficiency virus (HIV) type 2 proteinase in complex with a reduced amide inhibitor and comparison with HIV-1 proteinase structures
-
Tong, L., Pav, S., Pargellis, C., Do, F., Lamarre, D. and Anderson, P.C. Crystal structure of human immunodeficiency virus (HIV) type 2 proteinase in complex with a reduced amide inhibitor and comparison with HIV-1 proteinase structures. Proc. natn. Acad. Sci. U.S.A. 90, 8387-8391 (1993).
-
(1993)
Proc. Natn. Acad. Sci. U.S.A.
, vol.90
, pp. 8387-8391
-
-
Tong, L.1
Pav, S.2
Pargellis, C.3
Do, F.4
Lamarre, D.5
Anderson, P.C.6
-
10
-
-
0027742457
-
Three-dimensional structure of a simian immunodeficiency virus proteinase/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 proteinase inhibitors
-
Zhao, B., Winborne, E., Minnich, M.D., Culp, J.S., Debouck, C. and Abdel-Meguid, S.S. Three-dimensional structure of a simian immunodeficiency virus proteinase/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 proteinase inhibitors. Biochemistry 32, 13054-13060 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 13054-13060
-
-
Zhao, B.1
Winborne, E.2
Minnich, M.D.3
Culp, J.S.4
Debouck, C.5
Abdel-Meguid, S.S.6
-
11
-
-
0028233011
-
Alternative native flap conformation revealed by 2.3 A resolution structure of SIV proteinase
-
Wilderspin, A.F. and Sugrue, R.J. Alternative native flap conformation revealed by 2.3 A resolution structure of SIV proteinase. J molec. Biol. 239, 97-103 (1994).
-
(1994)
J Molec. Biol
, vol.239
, pp. 97-103
-
-
Wilderspin, A.F.1
Sugrue, R.J.2
-
12
-
-
84970062869
-
-
Levy, J.A, Plenum Press, New York
-
Pedersen, N.C. in: The Retroviridae (ed. Levy, J.A.) 181-228 (Plenum Press, New York; 1993).
-
(1993)
The Retroviridae
, pp. 181-228
-
-
Pedersen, N.C.1
-
13
-
-
0025727576
-
Simian and feline immunodeficiency viruses: Animal lentivlrus models for evaluation of AIDS vaccines and antiviral agents
-
Gardner, M.B. Simian and feline immunodeficiency viruses: animal lentivlrus models for evaluation of AIDS vaccines and antiviral agents. Antiviral Res. 15, 267-286 (1991).
-
(1991)
Antiviral Res
, vol.15
, pp. 267-286
-
-
Gardner, M.B.1
-
14
-
-
0026326170
-
Cloning, expression and kinetic characterization of the feline immunodeficiency virus proteinase
-
Farmerie, W.G., Goodenow, M.M. and Dunn, B.M. Cloning, expression and kinetic characterization of the feline immunodeficiency virus proteinase. Adv. exp. med. Biol. 306, 511-513 (1991).
-
(1991)
Adv. Exp. Med. Biol
, vol.306
, pp. 511-513
-
-
Farmerie, W.G.1
Goodenow, M.M.2
Dunn, B.M.3
-
15
-
-
0027528948
-
Identification of proteolytic processing sites within the Gag and Pol polyproteins of feline immunodeficiency virus
-
Elder, J.H. et al. Identification of proteolytic processing sites within the Gag and Pol polyproteins of feline immunodeficiency virus. J Virol. 67, 1869-1876 (1993).
-
(1993)
J Virol
, vol.67
, pp. 1869-1876
-
-
Elder, J.H.1
-
16
-
-
0000523078
-
Nucleotide sequence and genomic organization of feline immunodeficiency virus
-
Talbott, R.L. et al. Nucleotide sequence and genomic organization of feline immunodeficiency virus. Proc. natn. Acad. Sci. U S A. 86, 5743-5747 (1989).
-
(1989)
Proc. Natn. Acad. Sci. U S A
, vol.86
, pp. 5743-5747
-
-
Talbott, R.L.1
-
17
-
-
84970056922
-
-
Takahashi, KPlenum Publishing Corporation, New York
-
Gustchina, A. in Aspartic Proteinases (ed. Takahashi, K.) (Plenum Publishing Corporation, New York; 1995).
-
(1995)
Aspartic Proteinases
-
-
Gustchina, A.1
-
18
-
-
0028927329
-
Effect of point mutations on the kinetics and the inhibition of human immunodeficiency virus type 1 proteinase: Relationship to drug resistance
-
Lin, Y. et al. Effect of point mutations on the kinetics and the inhibition of human immunodeficiency virus type 1 proteinase: Relationship to drug resistance. Biochemistry 34, 1143-1152 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 1143-1152
-
-
Lin, Y.1
-
19
-
-
84970063789
-
-
Makarova, R.F., Scientific Center for Biological Publishing, Pushchino
-
Andreeva, N.S. in Structure and Biosynthesis of Proteins (ed. Makarova, R.F.) 97-114 (Scientific Center for Biological Publishing, Pushchino; 1988).
-
(1988)
Structure and Biosynthesis of Proteins
, pp. 97-114
-
-
Andreeva, N.S.1
-
20
-
-
0025221847
-
Domain communication in the dynamical structure of human immunodeficiency virus proteinase
-
Harte, W.E. Jr., Swaminathan, S., Mansuri, M.M., Martin, J.C., Rosenberg, I.E. and Beveridge, D.L., Domain communication in the dynamical structure of human immunodeficiency virus proteinase. Proc. natn. Acad. Sci. U.S.A. 87, 8864-8868 (1990).
-
(1990)
Proc. Natn. Acad. Sci. U.S.A.
, vol.87
, pp. 8864-8868
-
-
Harte, W.E.1
Swaminathan, S.2
Mansuri, M.M.3
Martin, J.C.4
Rosenberg, I.E.5
Beveridge, D.L.6
-
21
-
-
0025989978
-
Comparative analysis of the sequences and structures of HIV-1 and HIV-2 proteases
-
Gustchina, A. and Weber, I T. Comparative analysis of the sequences and structures of HIV-1 and HIV-2 proteases. Proteins 10, 325-339 (1991).
-
(1991)
Proteins
, vol.10
, pp. 325-339
-
-
Gustchina, A.1
Weber, I.T.2
-
22
-
-
0028302946
-
Human immunodeficiency virus type 1 protease inhibitors: Evaluation of resistance engendered by amino acid substitutions in the enzyme's substrate binding site
-
Sardana, V.V. et al. Human immunodeficiency virus type 1 protease inhibitors: Evaluation of resistance engendered by amino acid substitutions in the enzyme's substrate binding site. Biochemistry 33, 2004-2010 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 2004-2010
-
-
Sardana, V.V.1
-
23
-
-
0027219220
-
Vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 proteinase
-
Otto, MJ. et al. In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 proteinase. Proc. natn. Acad. Sci. U.S.A. 90, 7543-7547 (1993).
-
(1993)
Proc. Natn. Acad. Sci. U.S.A.
, vol.90
, pp. 7543-7547
-
-
Otto, M.J.1
-
24
-
-
0028014288
-
Characterization of human immunodeficiency virus type 1 variants with Increased resistance to a C2-symmetric proteinase inhibitor
-
Ho, D.D. et al. Characterization of human immunodeficiency virus type 1 variants with Increased resistance to a C2-symmetric proteinase inhibitor. J Virol. 68. 2016-2020 (1994).
-
(1994)
J Virol
, vol.68
, pp. 2016-2020
-
-
Ho, D.D.1
-
25
-
-
0028943992
-
Vivo emergence of HIV-1 variants resistant to multiple proteinase inhibitors
-
Condra, J.H. et al. In vivo emergence of HIV-1 variants resistant to multiple proteinase inhibitors. Nature 374, 569-571 (1995).
-
(1995)
Nature
, vol.374
, pp. 569-571
-
-
Condra, J.H.1
-
26
-
-
0026721254
-
Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing-hydrophobic*hydrophobic-or -aromatic*pro-cleavage sites
-
Griffiths, J.T. et al. Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing-hydrophobic*hydrophobic-or -aromatic*pro-cleavage sites. Biochemistry 31, 5193-5200 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 5193-5200
-
-
Griffiths, J.T.1
-
27
-
-
0025823572
-
On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces
-
Gellman, S.H. On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. Biochemistry 30, 6633-6636 (1991).
-
(1991)
Biochemistry
, vol.30
, pp. 6633-6636
-
-
Gellman, S.H.1
-
28
-
-
0027081927
-
Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modeling
-
Thanki, N. et al. Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: comparisons with molecular modeling. Prot. Sci. 1, 1061-1072 (1992).
-
(1992)
Prot. Sci
, vol.1
, pp. 1061-1072
-
-
Thanki, N.1
-
29
-
-
0027170695
-
Model peptides to study the effects of P2 and P3 substitutions in statine-containing HIV proteinase inhibitors
-
Hui, K.Y., Hermann, R.B., Manetta, J V., Gygi, T. and Angleton, E.L. Model peptides to study the effects of P2 and P3 substitutions in statine-containing HIV proteinase inhibitors. FEBS Lett. 327, 355-360 (1993).
-
(1993)
FEBS Lett
, vol.327
, pp. 355-360
-
-
Hui, K.Y.1
Hermann, R.B.2
Manetta, J.V.3
Gygi, T.4
Angleton, E.L.5
-
30
-
-
0028695485
-
-
d. Dunn, B.M. and Pennington, M.W., Humana Press, Totowa
-
Dunn, B.M., Scarborough, P.E., Davenport, R., and Swienicki, W. in: Methods in Molecular Biology (ed. Dunn, B.M. and Pennington, M.W.) 225-243 (Humana Press, Totowa; 1994).
-
(1994)
Methods in Molecular Biology
, pp. 225-243
-
-
Dunn, B.M.1
Scarborough, P.E.2
Davenport, R.3
Swienicki, W.4
-
32
-
-
0002701928
-
Phases-A program package for the processing and analysis of diffraction data for macromolecules
-
Furey, W. and Swaminathan, S. Phases-A program package for the processing and analysis of diffraction data for macromolecules. Acta crystallogr. (1990).
-
(1990)
Acta Crystallogr
-
-
Furey, W.1
Swaminathan, S.2
-
33
-
-
0022333121
-
Stereochemically restrained refinement of macromolecular structures
-
Hendrickson, W.A. Stereochemically restrained refinement of macromolecular structures. Meth. Enzymol. 115, 252-270 (1985).
-
(1985)
Meth. Enzymol
, vol.115
, pp. 252-270
-
-
Hendrickson, W.A.1
-
34
-
-
0002301187
-
Incorporation of fast Fourier transforms to speed restrained least-squares refinement of protein structures
-
Finzel, B.C. Incorporation of fast Fourier transforms to speed restrained least-squares refinement of protein structures. J appl. Crystallogr. 20, 53-55 (1987).
-
(1987)
J Appl. Crystallogr
, vol.20
, pp. 53-55
-
-
Finzel, B.C.1
|