4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: Implications for the mechanism of uterine tumorigenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 20, 1995, Pages 9220-9224

  Liehr, Joachim G ^a   Ricci, Mary Jo ^a   Jefcoate, Colin R ^b   Hannigan, Edward V ^a   Hokanson, James A ^a   Zhu, Bao Ting ^a,c  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

2 hydroxyestradiol; 4 hydroxyestradiol; cytochrome P450; estrogen metabolism; uterine myoma

Indexed keywords

4 HYDROXYESTRADIOL; CYTOCHROME P450; ESTRADIOL; FREE RADICAL;

ARTICLE; CARCINOGENESIS; FEMALE; HUMAN; HUMAN TISSUE; MICROSOME; MYOMETRIUM; OXIDATIVE STRESS; PRIORITY JOURNAL; UTERUS MYOMA;

BENZOFLAVONES; CELL TRANSFORMATION, NEOPLASTIC; COMPARATIVE STUDY; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; ESTRADIOL; ESTROGENS, CATECHOL; FEMALE; HUMAN; HYDROXYLATION; LEIOMYOMA; MICROSOMES; MYOMETRIUM; NAPHTHALENES; PHENANTHRENES; PLACENTA; PREGNANCY; SUPPORT, U.S. GOV'T, P.H.S.; UTERINE NEOPLASMS;

NOTOMYOTINA;

EID: 0029059604     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.20.9220     Document Type: Article

References (35)