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Volumn 15, Issue 7, 1995, Pages 3635-3643

Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PHEROMONE;

EID: 0029058433     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.15.7.3635     Document Type: Article
Times cited : (169)

References (54)
  • 2
    • 0024412926 scopus 로고
    • β-Adrenergic receptor kinase: Primary structure delineates a multigene family
    • Benovic, J. L., A. DeBlasi, W. C. Stone, M. G. Caron, and R. J. Lefkowitz. 1989. β-Adrenergic receptor kinase: primary structure delineates a multigene family. Science 246:235-240.
    • (1989) Science , vol.246 , pp. 235-240
    • Benovic, J.L.1    DeBlasi, A.2    Stone, W.C.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 3
    • 0024729959 scopus 로고
    • Regulation of postreceptor signaling in the pheromone response pathway of Saccharomyces cerevisiae
    • Blinder, D., and D. D. Jenness. 1989. Regulation of postreceptor signaling in the pheromone response pathway of Saccharomyces cerevisiae. Mol. Cell. Biol. 9:3720-3726.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 3720-3726
    • Blinder, D.1    Jenness, D.D.2
  • 4
    • 0025441553 scopus 로고
    • Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling
    • Blumer, K. J., and J. Thorner. 1990. Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc. Natl. Acad. Sci. USA 87:4363-4367.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4363-4367
    • Blumer, K.J.1    Thorner, J.2
  • 5
    • 12044260162 scopus 로고
    • Mutations that alter the third cytoplasmic loop of the a factor receptor lead to a constitutive and hypersensitive phenotype
    • Boone, C., N. G. Davis, and G. F. Sprague, Jr. 1993. Mutations that alter the third cytoplasmic loop of the a factor receptor lead to a constitutive and hypersensitive phenotype. Proc. Natl. Acad. Sci. USA 90:9921-9925.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9921-9925
    • Boone, C.1    Davis, N.G.2    Sprague Jr., G.F.3
  • 6
    • 0025010979 scopus 로고
    • The GTPase superfamily: A conserved switch for diverse cell functions
    • Bourne, H. R., D. A. Sanders, and P. McCormick. 1990. The GTPase superfamily: a conserved switch for diverse cell functions. Nature (London) 348: 125-132.
    • (1990) Nature (London) , vol.348 , pp. 125-132
    • Bourne, H.R.1    Sanders, D.A.2    McCormick, P.3
  • 7
    • 0022422406 scopus 로고
    • The yeast α-factor receptor: Structural properties deduced from the sequence of the STE2 gene
    • Burkholder, A. C., and L. H. Hartwell. 1985. The yeast α-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res. 13:8463-8475.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 8463-8475
    • Burkholder, A.C.1    Hartwell, L.H.2
  • 8
    • 0020040057 scopus 로고
    • 1 arrest by a-factor and α-factor pheromones
    • 1 arrest by a-factor and α-factor pheromones. Mol. Cell. Biol. 2:11-20.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 11-20
    • Chan, R.K.1    Otte, C.A.2
  • 9
    • 0020039329 scopus 로고
    • 1 arrest by a-factor and α-factor pheromones
    • 1 arrest by a-factor and α-factor pheromones. Mol. Cell. Biol. 2:21-29.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 21-29
    • Chan, R.K.1    Otte, C.A.2
  • 10
    • 0018699864 scopus 로고
    • Recovery of S. cerevisiae a cells from G1 arrest by α factor pheromone requires endopeptidase action
    • Ciejek, E., and J. Thorner. 1979. Recovery of S. cerevisiae a cells from G1 arrest by α factor pheromone requires endopeptidase action. Cell 18:623-635.
    • (1979) Cell , vol.18 , pp. 623-635
    • Ciejek, E.1    Thorner, J.2
  • 11
    • 0027495684 scopus 로고
    • New roles for G-protein βγ-dimers in transmembrane signalling
    • Clapham, D. E., and E. J. Neer. 1993. New roles for G-protein βγ-dimers in transmembrane signalling. Nature (London) 365:403-406.
    • (1993) Nature (London) , vol.365 , pp. 403-406
    • Clapham, D.E.1    Neer, E.J.2
  • 12
    • 0025969447 scopus 로고
    • Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone
    • Cole, G. M., and S. I. Reed. 1991. Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone. Cell 64:703-716.
    • (1991) Cell , vol.64 , pp. 703-716
    • Cole, G.M.1    Reed, S.I.2
  • 13
    • 0025019539 scopus 로고
    • Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway
    • Cole, G. M., D. E. Stone, and S. I. Reed. 1990. Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway. Mol. Cell. Biol. 10:510-517.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 510-517
    • Cole, G.M.1    Stone, D.E.2    Reed, S.I.3
  • 14
    • 0027318238 scopus 로고
    • Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors
    • Conklin, B. R., and H. R. Bourne. 1993. Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors. Cell 73:631-641.
    • (1993) Cell , vol.73 , pp. 631-641
    • Conklin, B.R.1    Bourne, H.R.2
  • 15
    • 0024442034 scopus 로고
    • A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae
    • Courchesne, W. E., R. Kunisawa, and J. Thorner. 1989. A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell 58:1107-1119.
    • (1989) Cell , vol.58 , pp. 1107-1119
    • Courchesne, W.E.1    Kunisawa, R.2    Thorner, J.3
  • 16
    • 0023460928 scopus 로고
    • Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: A model for desensitization to pheromone
    • Dietzel, C., and J. Kurjan. 1987. Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone. Mol. Cell. Biol. 7:4169-4177.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4169-4177
    • Dietzel, C.1    Kurjan, J.2
  • 17
    • 0023664976 scopus 로고
    • The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
    • Dietzel, C., and J. Kurjan. 1987. The yeast SCG1 gene: a Gα-like protein implicated in the a- and α-factor response pathway. Cell 50:1001-1010.
    • (1987) Cell , vol.50 , pp. 1001-1010
    • Dietzel, C.1    Kurjan, J.2
  • 18
    • 0027436527 scopus 로고
    • Pheromone action regulates G-protein α subunit myristoylation in the yeast Saccharomyces cerevisiae
    • Dohlman, H. G., P. Goldsmith, A. M. Spiegel, and J. Thorner. 1993. Pheromone action regulates G-protein α subunit myristoylation in the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90:9688-9692.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9688-9692
    • Dohlman, H.G.1    Goldsmith, P.2    Spiegel, A.M.3    Thorner, J.4
  • 20
    • 0025812324 scopus 로고
    • Model systems for the study of seven-transmembrane-segment receptors
    • Dohlman, H. G., J. Thorner, M. G. Caron, and R. J. Lefkowitz. 1991. Model systems for the study of seven-transmembrane-segment receptors. Annu. Rev. Biochem. 60:653-688.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 653-688
    • Dohlman, H.G.1    Thorner, J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 21
    • 0020645052 scopus 로고
    • Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente, L. 1983. Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101:181-191.
    • (1983) Methods Enzymol. , vol.101 , pp. 181-191
    • Guarente, L.1
  • 23
    • 0009447741 scopus 로고
    • Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: Gene sequence and implications for the structure of the presumed receptor
    • Hagen, D. C., G. McCaffrey, and G. F. Sprague, Jr. 1986. Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor. Proc. Natl. Acad. Sci. USA 83:1418-1422.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1418-1422
    • Hagen, D.C.1    McCaffrey, G.2    Sprague Jr., G.F.3
  • 24
    • 0025223081 scopus 로고
    • Turning off the signal: Desensitization of β-adrenergic receptor function
    • Hausdorff, W. P., M. G. Caron, and R. J. Lefkowitz. 1991. Turning off the signal: desensitization of β-adrenergic receptor function. FASEB J. 4:2881-2889.
    • (1991) FASEB J. , vol.4 , pp. 2881-2889
    • Hausdorff, W.P.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 25
    • 0023481280 scopus 로고
    • A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli
    • Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267-272.
    • (1987) Gene , vol.57 , pp. 267-272
    • Hoffman, C.S.1    Winston, F.2
  • 26
    • 0024021558 scopus 로고
    • Mutations in a gene encoding the α subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling
    • Jahng, K. Y., J. Ferguson, and S. I. Reed. 1988. Mutations in a gene encoding the α subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling. Mol. Cell. Biol. 8:2484-2493.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 2484-2493
    • Jahng, K.Y.1    Ferguson, J.2    Reed, S.I.3
  • 27
    • 0020724122 scopus 로고
    • Yeast α-factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase
    • Julius, D., L. Blair, A. Brake, G. Sprague, and J. Thorner. 1983. Yeast α-factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell 32:839-852.
    • (1983) Cell , vol.32 , pp. 839-852
    • Julius, D.1    Blair, L.2    Brake, A.3    Sprague, G.4    Thorner, J.5
  • 28
    • 0023724429 scopus 로고
    • The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
    • Konopka, J. B., D. D. Jenness, and L. H. Hartwell. 1988. The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone. Cell 54:609-620.
    • (1988) Cell , vol.54 , pp. 609-620
    • Konopka, J.B.1    Jenness, D.D.2    Hartwell, L.H.3
  • 29
    • 0026637326 scopus 로고
    • Pheromone response in yeast
    • Kurjan, J. 1992. Pheromone response in yeast. Annu. Rev. Biochem. 61: 1097-1129.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 1097-1129
    • Kurjan, J.1
  • 30
    • 0026028177 scopus 로고
    • Mutations in the guanine nucleotide-binding domains of a yeast Gα protein confer a constitutive or uninducible state to the pheromone response pathway
    • Kurjan, J., J. P. Hirsch, and C. Dietzel. 1991. Mutations in the guanine nucleotide-binding domains of a yeast Gα protein confer a constitutive or uninducible state to the pheromone response pathway. Genes Dev. 5:475-483.
    • (1991) Genes Dev. , vol.5 , pp. 475-483
    • Kurjan, J.1    Hirsch, J.P.2    Dietzel, C.3
  • 31
    • 0027091999 scopus 로고
    • Dominant-negative mutants of a yeast G-protein β subunit identify two functional regions involved in pheromone signalling
    • Leberer, E., D. Dignard, L. Hougan, D. Y. Thomas, and M. Whiteway. 1992. Dominant-negative mutants of a yeast G-protein β subunit identify two functional regions involved in pheromone signalling. EMBO J. 11:4805-4813.
    • (1992) EMBO J. , vol.11 , pp. 4805-4813
    • Leberer, E.1    Dignard, D.2    Hougan, L.3    Thomas, D.Y.4    Whiteway, M.5
  • 32
    • 0027194487 scopus 로고
    • G protein-coupled receptor kinases
    • Lefkowitz, R. J. 1993. G protein-coupled receptor kinases. Cell 74:409-412.
    • (1993) Cell , vol.74 , pp. 409-412
    • Lefkowitz, R.J.1
  • 33
    • 0025250147 scopus 로고
    • Multiple pathways of rapid β2-adrenergic receptor desensitization: Delineation with specific inhibitors
    • Lohse, M. J., J. L. Benovic, M. G. Caron, and R. J. Lefkowitz. 1990. Multiple pathways of rapid β2-adrenergic receptor desensitization: delineation with specific inhibitors. J. Biol. Chem. 265:3202-3209.
    • (1990) J. Biol. Chem. , vol.265 , pp. 3202-3209
    • Lohse, M.J.1    Benovic, J.L.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 35
    • 0028169361 scopus 로고
    • Degradation of G alpha by the N-end rule pathway
    • Madura, K., and A. Varshavsky. 1994. Degradation of G alpha by the N-end rule pathway. Science 265:1454-1458.
    • (1994) Science , vol.265 , pp. 1454-1458
    • Madura, K.1    Varshavsky, A.2
  • 36
    • 0024678964 scopus 로고
    • Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae
    • Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 9:2289-2297.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2289-2297
    • Miyajima, I.1    Arai, K.2    Matsumoto, K.3
  • 37
    • 0023665139 scopus 로고
    • GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in the mating factor-mediated signal transduction pathway
    • Miyajima, I., M. Nakafuku, N. Nakayama, C. Brenner, A. Miyajima, K. Kaibuchi, K. I. Arai, Y. Kaziro, and K. Matsumoto. 1987. GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in the mating factor-mediated signal transduction pathway. Cell 50:1011-1019.
    • (1987) Cell , vol.50 , pp. 1011-1019
    • Miyajima, I.1    Nakafuku, M.2    Nakayama, N.3    Brenner, C.4    Miyajima, A.5    Kaibuchi, K.6    Arai, K.I.7    Kaziro, Y.8    Matsumoto, K.9
  • 38
    • 0021332772 scopus 로고
    • Yeast cells recover from mating pheromone α factor-induced division arrest by desensitization in the absence of α-factor destruction
    • Moore, S. A. 1983. Yeast cells recover from mating pheromone α factor-induced division arrest by desensitization in the absence of α-factor destruction. J. Biol. Chem. 259:1004-1010.
    • (1983) J. Biol. Chem. , vol.259 , pp. 1004-1010
    • Moore, S.A.1
  • 39
    • 0001107597 scopus 로고
    • Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae
    • Nakayama, N., A. Miyajima, and K. Arai. 1985. Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae. EMBO J. 4:2643-2648.
    • (1985) EMBO J. , vol.4 , pp. 2643-2648
    • Nakayama, N.1    Miyajima, A.2    Arai, K.3
  • 40
    • 0025159301 scopus 로고
    • Regulation of the yeast pheromone response pathways by G protein subunits
    • Nomoto, S., N. Nakayama, K. Arai, and K. Matsumoto. 1990. Regulation of the yeast pheromone response pathways by G protein subunits. EMBO J. 9:691-696.
    • (1990) EMBO J. , vol.9 , pp. 691-696
    • Nomoto, S.1    Nakayama, N.2    Arai, K.3    Matsumoto, K.4
  • 41
    • 0026619906 scopus 로고
    • STE50, a novel gene required for activation of conjugation at an early step in mating in Saccharomyces cerevisiae
    • Rad, M. R., G. Xu, and C. P. Hollenberg. 1992. STE50, a novel gene required for activation of conjugation at an early step in mating in Saccharomyces cerevisiae. Mol. Gen. Genet. 236:145-154.
    • (1992) Mol. Gen. Genet. , vol.236 , pp. 145-154
    • Rad, M.R.1    Xu, G.2    Hollenberg, C.P.3
  • 42
    • 0024294018 scopus 로고
    • The carboxy-terminal segment of the yeast α-factor receptor is a regulatory do main
    • Reneke, J. E., K. J. Blumer, W. E. Courchesne, and J. Thorner. 1988. The carboxy-terminal segment of the yeast α-factor receptor is a regulatory do main. Cell 55:221-234.
    • (1988) Cell , vol.55 , pp. 221-234
    • Reneke, J.E.1    Blumer, K.J.2    Courchesne, W.E.3    Thorner, J.4
  • 43
    • 0024799254 scopus 로고
    • High efficiency transformation of intact yeast cells using single stranded nucleic acids as carrier
    • Schiestl, R. H., and R. D. Gietz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acids as carrier. Curr. Genet. 16:339-346.
    • (1989) Curr. Genet. , vol.16 , pp. 339-346
    • Schiestl, R.H.1    Gietz, R.D.2
  • 44
    • 0026090063 scopus 로고
    • In vitro mutagenesis and plasmid shuffling: From cloned gene to mutant yeast
    • Sikorski, R. S., and J. D. Boeke. 1991. In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast. Methods Enzymol. 194:302-318.
    • (1991) Methods Enzymol. , vol.194 , pp. 302-318
    • Sikorski, R.S.1    Boeke, J.D.2
  • 45
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 46
    • 0025971103 scopus 로고
    • Assay of yeast mating reaction
    • Sprague, G. F., Jr. 1991. Assay of yeast mating reaction. Methods Enzymol. 194:21-37.
    • (1991) Methods Enzymol. , vol.194 , pp. 21-37
    • Sprague Jr., G.F.1
  • 47
    • 0001134626 scopus 로고
    • Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae
    • J. R. Broach, J. R. Pringle, and E. W. Jones (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Sprague, G. F., Jr., and J. Thorner. 1992. Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae, p. 657-744. in J. R. Broach, J. R. Pringle, and E. W. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , pp. 657-744
    • Sprague Jr., G.F.1    Thorner, J.2
  • 48
    • 0024357961 scopus 로고
    • Isolation and characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by the mating hormone a factor
    • Steden, M., R. Betz, and W. Duntze. 1989. Isolation and characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by the mating hormone a factor. Mol. Gen. Genet. 219:439-444.
    • (1989) Mol. Gen. Genet. , vol.219 , pp. 439-444
    • Steden, M.1    Betz, R.2    Duntze, W.3
  • 49
    • 0025937311 scopus 로고
    • N-myristoylation is required for function of the pheromone-responsive Gα protein of yeast: Conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase
    • Stone, D. E., G. M. Cole, M. de Barros Lopes, M. Goebl, and S. I. Reed. 1991. N-myristoylation is required for function of the pheromone-responsive Gα protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes Dev. 5:1969-1981.
    • (1991) Genes Dev. , vol.5 , pp. 1969-1981
    • Stone, D.E.1    Cole, G.M.2    De Barros Lopes, M.3    Goebl, M.4    Reed, S.I.5
  • 50
    • 0025122575 scopus 로고
    • G protein mutations that alter the pheromone response in Saccharomyces cerevisiae
    • Stone, D. E., and S. I. Reed. 1990. G protein mutations that alter the pheromone response in Saccharomyces cerevisiae. Mol. Cell. Biol. 10:4439-4446.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4439-4446
    • Stone, D.E.1    Reed, S.I.2
  • 51
    • 0023376280 scopus 로고
    • Two genes required for cell fusion during yeast conjugation: Evidence for a pheromone-induced surface protein
    • Trueheart, J., J. D. Boeke, and G. R. Fink. 1987. Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol. Cell. Biol. 7:2316-2328.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2316-2328
    • Trueheart, J.1    Boeke, J.D.2    Fink, G.R.3
  • 52
    • 0027460543 scopus 로고
    • Disruption of receptor-G protein coupling in yeast promotes the function of an SST2-dependent adaptation pathway
    • Weiner, J. L., C. Guttieriez-Steil, and K. J. Blumer. 1993. Disruption of receptor-G protein coupling in yeast promotes the function of an SST2-dependent adaptation pathway. J. Biol. Chem. 268:8070-8077.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8070-8077
    • Weiner, J.L.1    Guttieriez-Steil, C.2    Blumer, K.J.3
  • 53
    • 0024966029 scopus 로고
    • The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptorcoupled G protein
    • Whiteway, M., L. Hougan, D. Dignard, D. Y. Thomas, L. Bell, G. C. Saari, F. J. Grant, P. O'Hara, and V. L. MacKay. 1989. The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptorcoupled G protein. Cell 56:467-477.
    • (1989) Cell , vol.56 , pp. 467-477
    • Whiteway, M.1    Hougan, L.2    Dignard, D.3    Thomas, D.Y.4    Bell, L.5    Saari, G.C.6    Grant, F.J.7    O'Hara, P.8    MacKay, V.L.9
  • 54
    • 0025191033 scopus 로고
    • Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae
    • Whiteway, M., L. Hougan, and D. Y. Thomas. 1990. Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae. Mol. Cell. Biol. 10:217-222.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 217-222
    • Whiteway, M.1    Hougan, L.2    Thomas, D.Y.3


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