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Volumn 36, Issue , 1995, Pages S2-S12

Antiepileptic Drug Mechanisms of Action

Author keywords

Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Ethosuximide; Gabapentin; Lamotrigine; Neuropharmacology; Phenytoin; Trimethadione; Valproate; Vigabatrin

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CALCIUM CHANNEL; CARBAMAZEPINE; ETHOSUXIMIDE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; SODIUM CHANNEL; VALPROIC ACID; VIGABATRIN;

EID: 0029057901     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1995.tb05996.x     Document Type: Article
Times cited : (450)

References (111)
  • 1
    • 0342930053 scopus 로고
    • Experimental anticonvulsive properties of GP 47 680 and of GP 47 779, its main human metabolite: compounds related to carbamazepine.
    • Meinardi H., Rowan, AJ., Amsterdam/ Lisse:, Swets and Zeitlinger
    • (1978) Advances in epileptology, 1977. , pp. 295-299
    • Baltzer, V.1    Schmulz, M.2
  • 7
    • 0024417584 scopus 로고
    • Pharmacokinetic effects of vigabatrin on cerebrospinal fluid amino acids in humans
    • SI2, 4
    • (1989) Epilepsia , vol.30
    • Ben‐Menachem, E.1
  • 8
    • 0019728938 scopus 로고
    • 3H]‐propyl‐β‐carboline‐3‐carboxylate as a selective radioligand for the BZI benzodiazepine receptor subclass
    • (1981) J Neurochem , vol.37 , pp. 333-341
    • Braestrup, C.1    Nielsen, MJ.2
  • 10
    • 0024280869 scopus 로고
    • Structure and function of voltage‐sensitive ion channels
    • (1988) Science , vol.242 , pp. 50-61
    • Catterall, WA.1
  • 25
    • 0027316231 scopus 로고
    • Primary structure and functional expression of the ω‐contotoxin‐sensitive N‐type calcium channel from rabbit brain
    • (1993) Neuron , vol.10 , pp. 585-598
    • Fujita, Y.1    Mynlieff, M.2    Kirksen, RT3
  • 27
    • 0019798267 scopus 로고
    • Increased gamma‐aminobutyric acid (GABA), homocarnosine and β‐alanine in cerebrospinal fluid of patients treated with gamma‐vinyl GABA (4‐amino‐hex‐5‐enoic acid)
    • (1981) Life Sci , vol.28 , pp. 2431-2439
    • Grove, J.1    Schechter, PJ2    Tell, G.3
  • 37
    • 0027511646 scopus 로고
    • Anticonvulsant action of oxycarbazepine, hydroxycarbamazepine, and carbamazepine against metrazol‐induced motor seizures in developing rats
    • (1993) Epilepsia , vol.34 , pp. 188-192
    • Kubova, H.1    Mares, P.2
  • 41
    • 0022900644 scopus 로고
    • Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action
    • (1986) Epilepsia , vol.27 , pp. 490-497
    • Leach, MJ1    Marden, CM2    Miller, AA.3
  • 42
    • 0027310109 scopus 로고
    • Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neuroglial cultures from rat cortex
    • (1993) Brain Res , vol.612 , pp. 190-199
    • Lees, G.1    Leach, MJ.2
  • 51
    • 0022540479 scopus 로고
    • Sodium valproate, but not ethosuximide, produces use‐ and voltage‐dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 1001-1011
    • McLean, MJ1    Macdonald, RL.2
  • 52
    • 0022516644 scopus 로고
    • Carbamazepine and 10,11‐epoxycarbamazepine produce use‐ and voltage‐dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture
    • (1986) J Pharmacol Exp Ther , vol.238 , pp. 727-732
    • McLean, MJ1    Macdonald, RL.2
  • 53
    • 0023832339 scopus 로고
    • Benzodiazepines, but not beta car‐bolines, limit high frequency repetitive firing of action potentials of spinal cord neurons in cell culture
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 789-795
    • McLean, MJ1    Macdonald, RL.2
  • 54
    • 0018118144 scopus 로고
    • Blockade of epileptic responses in photosensitive baboon Papio papio by two irreversible inhibitors of GABA‐transaminase, gamma‐acetylenic GABA (4‐amino‐hex‐5‐ynoic acid) and gamma‐vinyl GABA (4‐amino‐hex‐5‐enoic acid)
    • (1978) Psychopharmacologia , vol.59 , pp. 47-50
    • Meldrum, BS1    Horton, R.2
  • 60
    • 0002179111 scopus 로고
    • Lamotrigine blocks voltage‐dependent Na currents in a voltage‐dependent manner with a small use‐dependent component
    • (1993) Epilepsia , vol.34 , pp. 87
    • Mutoh, K.1    Dichter, MA.2
  • 63
    • 0344797034 scopus 로고
    • The ‐γ‐aminobutyric acid/benzodiazepine/barbiturate receptor‐chloride ion channel complex of mammalian brain.
    • Edelman Gall, Cowan, eds, New York:, John Wiley & Sons
    • (1987) Synaptic function. , pp. 257-271
    • Olsen, RW.1
  • 69
    • 0021036376 scopus 로고
    • Inhibition by GABA, baclofen, and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?
    • (1983) Eur J Pharmacol , vol.94 , pp. 341-344
    • Reimann, W.1
  • 73
    • 0025050694 scopus 로고
    • Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds
    • (1990) Pharmacol Rev , vol.42 , pp. 223-286
    • Rogawski, MA1    Porter, RJ.2
  • 78
    • 0017738744 scopus 로고
    • Tranier Y. Effects of elevated brain GABA concentrations on the action of bicuculline and picrotoxin in mice
    • (1977) Psychopharmacology , vol.54 , pp. 145-148
    • Schechter, PJ.1
  • 79
    • 0017662549 scopus 로고
    • Tranier Y, Jung MJ, Bohlen P. Audiogenic seizure protection by elevated brain GABA concentration in mice: effects of γ‐acetylenic GABA and ‐γ‐vinyl GABA, two irreversible GABA‐T inhibitors.
    • (1977) Eur J Pharmacol , vol.45 , pp. 319-328
    • Schechter, PJ.1
  • 86
    • 0024372376 scopus 로고
    • Phenytoin and carbamazepine: Potential‐and frequency‐dependent block of Na currents in mammalian myelinated nerve fibers
    • (1989) Epilepsia , vol.30 , pp. 286-294
    • Schwarz, J.1    Grigat, G.2
  • 99
    • 0024522273 scopus 로고
    • Sodium channels from human brain RN A expressed in Xenopus oocytes: basic electrophysiologic characteristics and their modifications by diphenylhy‐dantoin
    • (1989) J Clin Invest , vol.83 , pp. 1724-1732
    • Tomaselli, G.1    Marban, E.2    Yellen, G.3
  • 102
    • 0023600780 scopus 로고
    • Actions of benzodiazepine and β‐carboline derivatives on γ‐aminobutyric acid‐activated CI channels recorded from membrane patches of neonatal rat cortical neurons in culture
    • (1987) J Pharmacol Exper Ther , vol.243 , pp. 1195-1201
    • Vicini, S.1    Mienville, JM2    Costa, E.3
  • 104
    • 0040451444 scopus 로고
    • Effects of gabapentin on repetitive firing of action potentials and GABA responses of mouse central neurons in cell culture
    • (1991) Epilepsia , vol.32 , pp. 20-21
    • Wamil, AW1    Taylor, CP2    McLean, MJ.3
  • 107
    • 0024368757 scopus 로고
    • Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage‐dependent sodium current of isolated mammalian brain neurons
    • (1989) Brain Res , vol.494 , pp. 374-378
    • Wakamori, M.1    Kaneda, M.2    Oyama, Y.3    Akaike, N.4
  • 108
    • 0024600566 scopus 로고
    • Gating scheme for single GABA‐activated CI channels determined from stability plots, dwell‐time distributions, and adjacent‐interval durations
    • (1989) J Neurosci , vol.9 , pp. 1314-1324
    • Weiss, DS1    Magleby, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.