Phosphorylation and desensitization of the human β1-adrenergic receptor: Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase

Journal of Biological Chemistry

Volumn 270, Issue 30, 1995, Pages 17953-17961

  Freedman, Neil J ^a   Liggett, Stephen B ^a,b   Drachman, Douglas E ^a   Pei, Gang ^a   Caron, Marc G ^a   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINA S ANTIGEN; RHODOPSIN;

ARTICLE; CHINESE HAMSTER; DESENSITIZATION; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; ANTIGENS; BASE SEQUENCE; BUCLADESINE; CELL LINE; CRICETULUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA PRIMERS; EYE PROTEINS; FORSKOLIN; GENE EXPRESSION; GTP-BINDING PROTEINS; HAMSTERS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RECEPTORS, ADRENERGIC, BETA-1; SUPPORT, U.S. GOV'T, P.H.S.; TETRADECANOYLPHORBOL ACETATE;

EID: 0029057061     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.30.17953     Document Type: Article

References (48)

1. Brodde, O. E. (1993) Pharmacol. Ther. 60, 405-430
2. Arner, P., Kriegholm, E., and Engfeldt, P. (1991) J. Pharmacol. Exp. Ther. 259, 317-322
3. Kopp, U., and DiBona, G. (1983) Am. J. Physiol. 244, F418-F424
4. Lohse, M. (1993) Biochim. Biophys. Acta 1179, 171-188
5. Zhou, X. M., and Fishman, P. H. (1991) J. Biol. Chem. 266, 7462-7468
6. Frielle, T., Collins, S., Daniel, K. W., Caron, M. G., Lefkowitz, R. J., and Kobilka, B. K. (1987) Proc. Natl Acad. Sci. U. S. A. 84, 7920-7924
7. Inglese, J., Freedman, N. J., Koch, W. J., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 23735-23738
8. Lohse, M. J., Andexinger, S., Pitcher, J., Trukawinski, S., Codina, J., Faure, J. P., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 8558-8564
9. Attramadal, H., Arriza, J. L., Aoki, C., Dawson, T. M., Codina, J., Kwatra, M. M., Snyder, S. H., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 17882-17890
10. Premont, R. T., Koch, W. J., Inglese, J., and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 6832-6841
11. Ungerer, M., Bohm, M., Elce, J. S., Erdmann, E., and Lohse, M. J. (1993) Circulation 87, 454-463
12. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
13. Kolodziej, P. A., and Young, R, A. (1991) Methods Enzymol. 194, 508-519
14. Liggett, S. B., Freedman, N. J., Schwinn, D. A., and Lefkowitz, R. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3665-3669
15. Benovic, J. L., DeBlasi, A., Stone, W. C., Caron, M. G., and Lefkowitz, R. J. (1989) Science 246, 235-240
16. Benovic, J. L., Onorato, J. J., Arriza, J. L., Stone, W. C., Lohse, M., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Caron, M. G., and Lefkowitz, R. J. (1991) J. Biol. Chem. 266, 14939-14946
17. Lorenz, W., Inglese, J., Palczewski, K., Onorato, J., Caron, M., and Lefkowitz, R. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8715-8719
18. Dearry, A., Gingrich, J., Falardeau, P., Fremeau, R. J., Bates, M., and Caron, M. (1990) Nature 347, 72-76
19. O'Reilly, D., Miller, L., and Luckow, V. (1994) Baculovirus Expression Vectors: A Laboratory Manual, Oxford University Press, New York
20. Hausdorff, W. P., Bouvier, M., O'Dowd, B. F., Irons, G. P., Caron, M. G., and Lefkowitz, R. J. (1989) J. Biol. Chem. 264, 12657-12665
21. Didsbury, J., Uhing, R., Tomhave, E., Gerard, C., Gerard, N., and Snyderman, R. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 11564-11568
22. Salomon, Y. (1991) Methods Enzymol. 195, 22-29
23. Arriza, J. L., Dawson, T. M., Simerly, R. B., Martin, L. J., Caron, M. G., Snyder, S. H., and Lefkowitz, R. J. (1992) J. Neurosci. 12, 4045-4055
24. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
25. Sefton, B. M. (1991) Methods Enzymol. 201, 245-251
26. Pei, G., Tiberi, M., Caron, M. G., and Lefkowitz, R. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3633-3636
27. Barak, L. S., Tiberi, M., Freedman, N. J., Kwatra, M. M., Lefkowitz, R. J., and Caron, M. G. (1994) J. Biol. Chem. 269, 2790-2795
28. Colton, T. (1974) Statistics in Medicine, Little Brown and Co., Boston, MA
29. Lohse, M. J., Benovic, J. L., Caron, M. G., and Lefkowitz, R. J. (1990) J. Biol. Chem. 265, 3202-3211
30. Kong, G., Penn, R., and Benovic, J. L. (1994) J. Biol. Chem. 269, 13084-13087
31. Shih, M., and Malbon, C. C. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 12193-12197
32. Chijiwa, T., Mishima, A., Hagiwara, M., Sano, M., Hayashi, K., Inoue, T., Naito, K., Toshioka, T., and Hidaka, H. (1990) J. Biol. Chem. 265, 5267-5272
33. Roth, N. S., Campbell, P. T., Caron, M. G., Lefkowitz, R. J., and Lohse, M. J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6201-6204
34. Green, S. A., Holt, B. D., and Liggett, S. B. (1992) Mol. Pharmacol. 41, 889-893
35. Levy, F. O., Kaumann, A. J., and Birnbaumer, L. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10798-10802
36. Green, S. A., and Liggett, S. B. (1994) J. Biol. Chem. 269, 26215-26219
37. Strasser, R. H., Sibley, D. R., and Lefkowitz, R. J. (1986) Biochemistry 25, 1371-1377
38. Chen C.-Y., Dion, S. B., Kim, C. M., and Benovic, J. L. (1993) J. Biol. Chem. 268, 7825-7831
39. Lohse, M. J., Lefkowitz, R. J., Caron, M. G., and Benovic, J. L. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 3011-3015
40. Esbenshade, T. A., Han, C., Theroux, T. L., Ganneman, J. G., and Minneman, K. P. (1992) Mol. Pharmacol 42, 753-759
41. Bristow, M. R., Hershberger, R. E., Port, J. D., Minobe, W., and Rasmussen, R. (1989) Mol. Pharmacol. 35, 295-303
42. Hammond, H. K., Roth, D. A., Insel, P. A., Ford, C. E., White, F. C., Maisel, A. S., Ziegler, M. G., and Bloor, C. M. (1992) Circulation 85, 269-280
43. Koch, W. J., Rockman, H. A., Samama, P., Hamilton, R., Bond, R. A., Milano, C. A., and Lefkowitz, R. J. (1995) Science, 268, 1350-1353
44. Kunapuli, P., Onarato, J. J., Hosey, M. M., and Benovic, J. L. (1994) J. Biol. Chem. 269, 1099-1105
45. Onorato, J. J., Palczewski, K., Regan, J. W., Caron, M. G., Lefkowitz, R. J., and Benovic, J. L. (1991) Biochemistry 30, 5118-5125
46. Burgermeister, W., Nassal, M., Wieland, T., and Helmreich, E. J. M. (1983) Biochim. Biophys. Acta 729, 219-228
47. Ping, P., Lynch, E., and Hammond, H. K. (1994) Circulation 90, 358
48. Zhou, X.-M., Pak, M., Wang, Z., and Fishman, P. H. (1995) Cell. Signalling 7, 202-217