Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

Cancer Chemotherapy and Pharmacology

Volumn 36, Issue 4, 1995, Pages 305-315

  Supko, Jeffrey G ^a   Hickman, Robert L ^b   Grever, Michael R ^a   Malspeis, Louis ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

Author keywords

Ansamycins; Antineoplastic agents; Pharmacokinetics

Indexed keywords

AMINOTRANSFERASE; ANSAMYCIN DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; GELDANAMYCIN;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; GASTROINTESTINAL TOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; LIVER TOXICITY; MALE; MEAN RESIDENCE TIME; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ANIMAL; ANTIBIOTICS, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HALF-LIFE; HUMAN; LIVER; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; NECROSIS; QUINONES; TUMOR CELLS, CULTURED;

EID: 0029056501     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/BF00689048     Document Type: Article

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