Molecular and epidemiological analyses of abnormal expression of aromatase in breast cancer

Pharmacogenetics

Volumn 5, Issue , 1995, Pages S59-S64

  Harada, Nobuhiro ^a   Utsumi, Toshiaki ^a   Takagi, Yasuyuki ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; COMPLEMENTARY DNA; ESTROGEN; MESSENGER RNA;

ADIPOSE TISSUE; BREAST CANCER; CONFERENCE PAPER; CONTROLLED STUDY; EPIDEMIOLOGY; EXON; FEMALE; FETUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER; LYMPH NODE METASTASIS; MALE; MOLECULAR BIOLOGY; OVARY; PRIORITY JOURNAL; PROMOTER REGION; TESTIS; TISSUE SPECIFICITY;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AROMATASE; BRAIN; BREAST NEOPLASMS; DNA, COMPLEMENTARY; EXONS; FEMALE; FETUS; GENE EXPRESSION; HUMAN; MALE; MIDDLE AGE; PLACENTA; PREGNANCY; PROSTATE; RNA, MESSENGER; SKIN; SUPPORT, NON-U.S. GOV'T; TESTIS;

EID: 0029055705     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199512001-00002     Document Type: Article

References (22)

1. Berkovitz GD, Fujimoto M, Brown TR, Brodie AM, Migeon CJ. Aromatase activity in cultured human genital skin fibroblasts. J Clin Endocrinol Metab 1984: 59, 665-671.
2. Chirgwin JM, Przybla AE, MacDonald KJ, Utter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979: 18, 5294-5299.
3. Esteban JM, Warsi Z, Haniu M, Hall P, Shively JE, Shiuan Chen. Detection of intratumoral aromatase in breast carcinomas: an immunohistochemical study with clinicopathologic correlation. Am J Pathol 1992: 140, 337-343.
4. Grodin JM, Siiteri PK, MacDonald PC. Source of estrogen production in the postmenopausal woman. J Clin Endocrinol Metab 1973: 36, 207-214.
5. Harada N, Yamada K. Ontogeny of aromatase messenger ribonucleic acid in mouse brain: fluorometrical quantitation by polymerase chain reaction. Endocrinology 1992:131, 2306-2312.
6. Harada N, Yamada K, Saito K, Kibe N, Dohmae S, Takagi Y. Structural characterization of the human estrogen synthetase (aromatase) gene. Biochem Biophys Res Commun 1990: 166, 365-372.
7. Harada N, Yamada K, Foidart A, Balthazart J. Regulation of aromatase cytochrome P-450 (estrogen synthetase) transcripts in the quail brain by testosterone. Mol Brain Res 1992 15, 19-26.
8. Harada N, Utsumi T, Takagi Y. Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proc Natl Acad Sci USA 1993: 90, 11 312-11 316.
9. Kilgore MW, Means GD, Mendelson CR, Simpson ER. Alternative promotion of aromatase P-450 expression in the human placenta. Molec Cell Endocrinol 1992: 83, R9-R16.
10. Lipton A, Santner SJ, Santen RJ, Harvey HA, Feil PD, White-Hershey D, Bartholomew MJ, Antle CE. Aromatase activity in primary and metastatic human breast cancer. Cancer 1987: 59, 779-782.
11. Mahendroo MS, Mendelson CR, Simpson ER. Tissue-specific and hormonally controlled alternative promoters regulate aroma-tase cytochrome P-450 gene expression in human adipose tissue. J Biol Chem 1993: 268, 19463-19470.
12. McNatty KP, Baird DT, Bolton A, Chambers P, Corker CS, MacLean H. Conversion of oestrogens and androgens in human ovarian venous plasma and follicular fluid throughout the menstrual cycle. J Endocrinol 1976: 71. 77-85.
13. Means GD, Mahendroo MS, Corbin CJ, Mathis MJ, Powell FE, Mendelson CR, Simpson ER. Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. J Biol Chem 1989: 264, 19385-19391.
14. Mendelson CR, Cleland WH, Smith ME, Simpson ER. Regulation of aromatase activity of stromal cells derived from human adipose tissue. Endocrinology 1982: 111, 1077-1085.
15. Miller WR, Mullen P. Factors influencing aromatase activity in the breast. J Steroid Biochem Molec Biol 1993: 44, 597-604.
16. Naftolin F, Ryan KJ, Davis IJ, Reddy VV, Flores F, Petro Z, Huhn M. The formation of estrogen by central neuroendocrine tissues. Recent Prog Horm Res 1975: 31, 295-315.
17. O'Neill JS, Elton RA, Miller WR. Aromatase activity in adipose tissue from breast quadrants: a link with tumour site. Br Med J 1988: 296, 741-743.
18. Ryan KJ. Biological aromatization of steroids. J Biol Chem 1959: 234, 268-272.
19. Santen RJ. Introduction to the conference, aromatase: new perspectives for breast cancer. Cancer Res 1982: 42, 3268s.
20. Santen RJ, Martel J, Hoagland M, Naftolin F, Roa L, Harada N, Hafer L, Zaino R, Santner SJ. Stromal spindle cells contain aromatase in human breast tumors. J Clin Endocrinol Metab 1994: 79, 627-632.
21. Smuk M, Schwers J. Aromatization of androstenedione by human adult liver in vitro. J Clin Endocrinol Metab 1977: 45, 1009-1012.
22. Toda K, Terashima M, Kawamoto T, Sumimoto H, Yokoyama Y, Kuribayashi I, Mitsuuchi Y, Maeda T, Yamamoto Y, Sagara Y, Ikeda H, Shizuta Y. Structural and functional characterization of human aromatase P450 gene. Eur J Biochem 1990: 193, 559-565.